JP2750557B2 - 豚ミステリー病に関連するウイルス性因子 - Google Patents

豚ミステリー病に関連するウイルス性因子

Info

Publication number
JP2750557B2
JP2750557B2 JP4252086A JP25208692A JP2750557B2 JP 2750557 B2 JP2750557 B2 JP 2750557B2 JP 4252086 A JP4252086 A JP 4252086A JP 25208692 A JP25208692 A JP 25208692A JP 2750557 B2 JP2750557 B2 JP 2750557B2
Authority
JP
Japan
Prior art keywords
virus
atcc
cell line
sirs
swine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP4252086A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05276940A (ja
Inventor
ダニー、ダブリュー、チュラデック
デイビッド、イー、ゴルシカ
ルイス、エル、ハリス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BEERINGAA INGERUHAIMU ANIMARU HERUSU Inc
Original Assignee
BEERINGAA INGERUHAIMU ANIMARU HERUSU Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27419390&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2750557(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by BEERINGAA INGERUHAIMU ANIMARU HERUSU Inc filed Critical BEERINGAA INGERUHAIMU ANIMARU HERUSU Inc
Publication of JPH05276940A publication Critical patent/JPH05276940A/ja
Application granted granted Critical
Publication of JP2750557B2 publication Critical patent/JP2750557B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10051—Methods of production or purification of viral material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP4252086A 1991-08-26 1992-08-26 豚ミステリー病に関連するウイルス性因子 Expired - Lifetime JP2750557B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US74983991A 1991-08-26 1991-08-26
US749839 1991-08-26
US84169292A 1992-02-26 1992-02-26
US92189192A 1992-08-05 1992-08-05
US921891 1992-08-05
US841692 1992-08-05

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP8118276A Division JPH08295636A (ja) 1991-08-26 1996-04-15 豚ミステリー病ワクチン

Publications (2)

Publication Number Publication Date
JPH05276940A JPH05276940A (ja) 1993-10-26
JP2750557B2 true JP2750557B2 (ja) 1998-05-13

Family

ID=27419390

Family Applications (2)

Application Number Title Priority Date Filing Date
JP4252086A Expired - Lifetime JP2750557B2 (ja) 1991-08-26 1992-08-26 豚ミステリー病に関連するウイルス性因子
JP8118276A Pending JPH08295636A (ja) 1991-08-26 1996-04-15 豚ミステリー病ワクチン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP8118276A Pending JPH08295636A (ja) 1991-08-26 1996-04-15 豚ミステリー病ワクチン

Country Status (15)

Country Link
US (1) US5476778A (enExample)
EP (1) EP0529584B1 (enExample)
JP (2) JP2750557B2 (enExample)
KR (1) KR0138092B1 (enExample)
AT (1) ATE140238T1 (enExample)
CA (1) CA2076744C (enExample)
DE (1) DE59206730D1 (enExample)
DK (1) DK0529584T3 (enExample)
ES (1) ES2089316T3 (enExample)
GR (1) GR3020603T3 (enExample)
HU (1) HU216311B (enExample)
MX (1) MX9204885A (enExample)
PL (1) PL169952B1 (enExample)
SG (1) SG45288A1 (enExample)
TW (1) TW289050B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011041534A (ja) * 2009-08-24 2011-03-03 Zenkoku Nogyo Kyodo Kumiai Rengokai 弱毒ウイルスの作出方法

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69201441T3 (de) 1991-06-06 2008-12-04 Boehringer Ingelheim Vetmedica Gmbh Erreger der mysteriösen schweinekrankheit,impfstoff-zusammensetzungen und diagnose kits.
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
US5846805A (en) 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
US6080570A (en) * 1991-08-26 2000-06-27 Boehringer Ingelheim Vetmedica, Inc. Method of producing a vaccine for Swine Infertility and Respiratory Syndrome
US6982160B2 (en) * 1991-08-26 2006-01-03 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions that include SIRS virus
AU2684792A (en) * 1991-10-14 1993-05-21 Akzo Nobel N.V. Porcine reproductive respiratory syndrome vaccine and diagnostic
FR2686097B1 (fr) * 1992-01-14 1994-12-30 Rhone Merieux Preparation d'antigenes et de vaccins de virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US6251397B1 (en) 1992-10-30 2001-06-26 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus and immunogenic compositions containing the same
PL178609B1 (pl) * 1993-02-08 2000-05-31 Bayer Ag Izolat wirusa zespołu reprodukcyjnego i oddechowego świń zwanego PRRSV, sposób namnażania izolatu PRRSV, klon linii komórkowej, hodowla tkankowa zawierająca izolat PRRSV, szczepionka efektywna w ochronie świń przeciw PRRSV oraz sposób wytwarzania szczepionki efektywnej w ochronie świń przeciw PRRSV
DE69522984T2 (de) * 1994-04-11 2002-04-25 Akzo Nobel Nv Europäische Vakzinstämme des Fortplanzungs-Atmungs-Syndromsvirus des Schweins
DK53595A (da) * 1994-05-13 1995-11-14 Iberica Cyanamid Rekombinante PRRSV-proteiner, diagnostiske kits og vaccine indeholdende sådanne rekombinante PRRSV-proteiner
ES2102971B1 (es) * 1996-01-25 1998-03-01 Hipra Lab Sa Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion.
US5866401A (en) * 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
US5976537A (en) * 1996-07-02 1999-11-02 The United States Of America As Represented By The Secretary Of Agriculture Porcine reproductive and respiratory syndrome vaccine
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
EP1882696A3 (en) 1997-05-06 2008-03-05 Boehringer Ingelheim Vetmedica Gmbh PRRSV antigenic sites identifying peptide sequences of PRRS virus for use in vaccines or diagnostic assays
NZ513289A (en) 1998-12-22 2003-04-29 Pfizer Prod Inc Infectious cDNA clone of north american procine reproductive and respiratory syndrome (PRRS) virus and uses thereof
JP3961222B2 (ja) 1999-03-08 2007-08-22 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー Ｐｒｒｓｖワクチン
EP1183332B1 (en) 1999-04-22 2010-07-14 United States Department Of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142
US6841364B2 (en) * 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof
US7906311B2 (en) * 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
CA2571452A1 (en) 2004-06-18 2006-01-26 Regents Of The University Of Minnesota Identifying virally infected and vaccinated organisms
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
WO2006053061A2 (en) * 2004-11-10 2006-05-18 Kansas State University Research Foundation Porcine reproductive and respiratory syndrome virus receptor components and uses thereof
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
PL1904631T3 (pl) 2005-06-24 2012-10-31 Univ Minnesota Wirusy PRRS, klony zakaźne, ich mutanty i sposoby stosowania
CA2635430A1 (en) 2005-12-29 2007-08-23 Boehringer Ingelheim Vetmedica, Inc. Use of a pcv2 immunogenic composition for lessening clinical symptoms in pigs
DK2275132T3 (da) 2005-12-29 2021-05-17 Boehringer Ingelheim Animal Health Usa Inc Multivalente pcv2-immunogeniske sammensætninger og fremgangsmåder til at fremstille dem
PT2094872T (pt) 2006-12-15 2017-04-27 Boehringer Ingelheim Vetmedica Inc Tratamento de porcos seropositivos para o anticorpo anti-pcv2 com antigénio de pcv2
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
PL2106440T3 (pl) * 2007-01-12 2016-02-29 Univ Illinois Komórki niepochodzące od małp do hodowli wirusa zespołu rozrodczo-oddechowego świń (PRRS)
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
WO2008109237A2 (en) * 2007-02-13 2008-09-12 Washington State University Research Foundation Macrophage cell-lines for propagation of porcine reproductive and respiratory syndrome virus
US7666585B2 (en) * 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
ES2389748T3 (es) * 2007-06-25 2012-10-31 South Dakota State University Virus del síndrome reproductivo y respiratorio porcino de tipo 1 norteamericano recombinante y métodos de uso
JP5619004B2 (ja) * 2008-08-25 2014-11-05 ベーリンガーインゲルハイム フェトメディカ インコーポレイテッド 高病原性ブタ繁殖・呼吸障害症候群（ｈｐｐｒｒｓ）のワクチン
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
KR200452417Y1 (ko) * 2011-01-21 2011-02-25 임진재 원통형 쿠션 벨트를 이용한 소파 쿠션장치
WO2012110489A2 (en) 2011-02-17 2012-08-23 Boehringer Ingelheim Vetmedica Gmbh Novel european prrsv strain
AU2012217170B2 (en) * 2011-02-17 2016-07-28 Boehringer Ingelheim Vetmedica Gmbh Commercial scale process for production of PRRSV
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
MX2014013964A (es) * 2012-05-17 2015-03-04 Zoetis Llc Vacunacion eficaz contral el virus del sindrome reproductivo y respiratorio porcino (prrs) antes del destete.
EP2929018A4 (en) 2012-12-07 2016-07-13 Univ Illinois COMPOSITIONS FROM THE REPRODUCTIVE SWINE VIRUS AND A VIRUS FOR THE RESPIRATORY SYNDROME AND USES THEREOF
US9579373B2 (en) 2013-03-15 2017-02-28 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
ES2778425T3 (es) 2013-10-02 2020-08-10 Boehringer Ingelheim Animal Health Usa Inc Variante de la proteína ORF2 del PCV2 y partículas similares a virus compuestas por esta
BR112019010394A2 (pt) 2016-11-29 2019-09-03 Intervet International B.V. vacina suína
UA124976C2 (uk) 2016-12-14 2021-12-22 Зоетіс Сервісіз Ллс Вакцина для захисту тварини свині від зараження вірусом prrs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
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FR2602791B1 (fr) * 1986-08-18 1988-11-10 Ministere Agri Direction Quali Procede de culture du virus de la rhinotracheite infectieuse de la dinde, et vaccin prepare a partir du virus ainsi obtenu

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011041534A (ja) * 2009-08-24 2011-03-03 Zenkoku Nogyo Kyodo Kumiai Rengokai 弱毒ウイルスの作出方法

Also Published As

Publication number Publication date
EP0529584B1 (de) 1996-07-10
DE59206730D1 (de) 1996-08-14
SG45288A1 (en) 1998-01-16
GR3020603T3 (en) 1996-10-31
US5476778A (en) 1995-12-19
DK0529584T3 (da) 1996-08-12
HUT62323A (en) 1993-04-28
PL295727A1 (en) 1993-05-17
KR0138092B1 (ko) 1998-04-30
EP0529584A2 (de) 1993-03-03
HU216311B (hu) 1999-06-28
KR930004459A (ko) 1993-03-22
ATE140238T1 (de) 1996-07-15
CA2076744A1 (en) 1993-02-27
EP0529584A3 (en) 1993-04-14
JPH08295636A (ja) 1996-11-12
PL169952B1 (pl) 1996-09-30
MX9204885A (es) 1994-05-31
TW289050B (enExample) 1996-10-21
CA2076744C (en) 2000-06-27
JPH05276940A (ja) 1993-10-26
ES2089316T3 (es) 1996-10-01

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