JP2675676B2 - 生物学的液体中の抗体を決定する免疫学的分析方法とその方法を実施するキット - Google Patents

生物学的液体中の抗体を決定する免疫学的分析方法とその方法を実施するキット

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Publication number
JP2675676B2
JP2675676B2 JP5501305A JP50130593A JP2675676B2 JP 2675676 B2 JP2675676 B2 JP 2675676B2 JP 5501305 A JP5501305 A JP 5501305A JP 50130593 A JP50130593 A JP 50130593A JP 2675676 B2 JP2675676 B2 JP 2675676B2
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JP
Japan
Prior art keywords
antibody
antigen
solid phase
immobilized
autoantibodies
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Expired - Lifetime
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JP5501305A
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English (en)
Japanese (ja)
Other versions
JPH06501103A (ja
Inventor
アンドレアス，ベルクマン
Original Assignee
ベー・エル・アー・ハー・エム・エス・ディアグノスティカ ゲーエムベーハー
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6434394&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2675676(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ベー・エル・アー・ハー・エム・エス・ディアグノスティカ ゲーエムベーハー filed Critical ベー・エル・アー・ハー・エム・エス・ディアグノスティカ ゲーエムベーハー
Publication of JPH06501103A publication Critical patent/JPH06501103A/ja
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Publication of JP2675676B2 publication Critical patent/JP2675676B2/ja
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Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP5501305A 1991-06-20 1992-06-15 生物学的液体中の抗体を決定する免疫学的分析方法とその方法を実施するキット Expired - Lifetime JP2675676B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4120412A DE4120412C1 (https=) 1991-06-20 1991-06-20
DE4120412.3 1991-06-20
PCT/EP1992/001348 WO1993000587A1 (de) 1991-06-20 1992-06-15 Immunologisches bestimmungsverfahren zur bestimmung von antikörpern in biologischen flüssigkeiten sowie kit zur durchführung des verfahrens

Publications (2)

Publication Number Publication Date
JPH06501103A JPH06501103A (ja) 1994-01-27
JP2675676B2 true JP2675676B2 (ja) 1997-11-12

Family

ID=6434394

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5501305A Expired - Lifetime JP2675676B2 (ja) 1991-06-20 1992-06-15 生物学的液体中の抗体を決定する免疫学的分析方法とその方法を実施するキット

Country Status (9)

Country Link
US (1) US5501955A (https=)
EP (1) EP0544869B2 (https=)
JP (1) JP2675676B2 (https=)
AT (1) ATE132976T1 (https=)
CA (1) CA2089870C (https=)
DE (2) DE4120412C1 (https=)
DK (1) DK0544869T3 (https=)
ES (1) ES2081115T3 (https=)
WO (1) WO1993000587A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5515705A (en) * 1992-01-23 1996-05-14 Board Of Regents, The University Of Texas System Apparatus and method for deforming a workpiece
DE4243375C2 (de) * 1992-12-21 1998-04-23 Brahms Diagnostica Gmbh Bestimmungsverfahren zur Bestimmung von Antikörpern in biologischen Flüssigkeiten
DE4323436C2 (de) * 1993-07-13 1995-06-08 Henning Berlin Gmbh Verfahren zur quantitativen Bestimmung von humaner Thyreoidaler Peroxidase und Kit für die Durchführung des Verfahrens
DE4343255A1 (de) * 1993-07-13 1995-06-22 Henning Berlin Gmbh Verfahren zur quantitativen Bestimmung von humaner Thyreoidaler Peroxidase und Kit für die Durchführung des Verfahrens
DE4328070C1 (de) * 1993-08-20 1994-11-24 Henning Berlin Gmbh Verfahren zur Bestimmung eines Analyten in einem Volumen einer flüssigen Probe sowie seine Anwendung zur Bestimmung von anti-TSH-Rezeptor-Autoantikörpern in einem Patientenserum
DE19505266C1 (de) * 1995-02-16 1996-10-02 Brahms Diagnostica Gmbh Verwendung von polyklonalen humanen anti-hTg-Autoantikörpern als Reagenz für die klinische Diagnostik von Schilddrüsen-Autoimmunerkrankungen sowie Reagenziensatz für eine Bestimmung von anti-hTg-Autoantikörpern in Patientenseren
DE19527160C1 (de) * 1995-07-25 1997-01-23 Brahms Diagnostica Gmbh Verfahren zur Messung der Konzentration eines Enzyms durch photometrische Absorptionsmessung eines enzymatisch gebildeten Farbstoffs in einer Meßlösung
DE19651093C2 (de) 1996-12-09 1999-06-10 Brahms Diagnostica Gmbh Rezeptorbindungsassay zum Nachweis von TSH-Rezeptor-Autoantikörpern sowie Reagenziensatz für die Durchführung eines solchen Rezeptorbindungsassays
DE19710211C2 (de) * 1997-03-12 1999-12-16 Brahms Diagnostica Gmbh Verfahren zur Bestimmung von Schilddrüsen-Autoantikörpern
GB9719357D0 (en) * 1997-09-11 1997-11-12 Ortho Clinical Diagnostics Immunoassay Utilizing Two Incubations With Labelled Antigen
GB9810040D0 (en) 1998-05-11 1998-07-08 Univ Nottingham Blood borne tumour markers
GB9823397D0 (en) * 1998-10-27 1998-12-23 Rsr Ltd Assays for thyroid autoantibodies
GB9827228D0 (en) * 1998-12-10 1999-02-03 Univ Nottingham Cancer detection method and reagents
US20030232399A1 (en) * 2000-06-14 2003-12-18 Robertson John Forsyth Russell Cancer detection methods and reagents
GB2424273B (en) * 2002-11-14 2007-06-27 Univ Nottingham Method for preparing tumour marker protein
SI1889059T1 (sl) 2005-05-27 2009-12-31 Oncimmune Ltd Izboljšani imunotestni postopek
GB2426581A (en) * 2005-05-27 2006-11-29 Univ Nottingham Immunoassay methods
US8574848B2 (en) 2006-09-13 2013-11-05 Oncimmune Ltd. Immunoassay methods
US8796039B2 (en) 2007-08-06 2014-08-05 Chugai Seiyaku Kabushiki Kaisha Method for measuring inhibitory activity on ligand-receptor binding
GB0725239D0 (en) * 2007-12-24 2008-02-06 Oncimmune Ltd Calibrator for autoantibody assay
WO2019014028A1 (en) * 2017-07-13 2019-01-17 Magarray, Inc. METHOD FOR QUANTIFYING AUTO-ANTIBODIES
CN113156129B (zh) * 2021-01-13 2022-04-05 广东菲鹏生物有限公司 中和抗体高敏检测方法及产品

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
US4469787A (en) * 1982-05-14 1984-09-04 Mallinckrodt Inc. Immunoassay involving soluble complex of second antibody and labeled binding protein
IL73938A (en) * 1984-01-02 1989-09-28 Boehringer Mannheim Gmbh Process and reagent for the determination of polyvalent antigen by incubation with three different receptors
JPS61271457A (ja) * 1985-05-28 1986-12-01 Olympus Optical Co Ltd 免疫学的分析方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
「酵素免疫測定法 第３版」昭和６２年５月１５日発行 石川栄治編．医学書院 ｐ３１〜３５

Also Published As

Publication number Publication date
JPH06501103A (ja) 1994-01-27
US5501955A (en) 1996-03-26
CA2089870C (en) 2003-09-09
DE4120412C1 (https=) 1993-01-07
EP0544869B2 (de) 2001-09-05
EP0544869A1 (de) 1993-06-09
ES2081115T3 (es) 1996-02-16
DE59205012D1 (de) 1996-02-22
WO1993000587A1 (de) 1993-01-07
CA2089870A1 (en) 1992-12-21
EP0544869B1 (de) 1996-01-10
ATE132976T1 (de) 1996-01-15
DK0544869T3 (da) 1996-02-26

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