JP2611003B2 - 免疫促進剤 - Google Patents

免疫促進剤

Info

Publication number
JP2611003B2
JP2611003B2 JP1194406A JP19440689A JP2611003B2 JP 2611003 B2 JP2611003 B2 JP 2611003B2 JP 1194406 A JP1194406 A JP 1194406A JP 19440689 A JP19440689 A JP 19440689A JP 2611003 B2 JP2611003 B2 JP 2611003B2
Authority
JP
Japan
Prior art keywords
hydrogen
group
acyl group
formula
immunostimulant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP1194406A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0278621A (ja
Inventor
ゲナーリ フェデルコ
バッシ ルイギ
Original Assignee
バイオリサーチ エス ピー エイ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バイオリサーチ エス ピー エイ filed Critical バイオリサーチ エス ピー エイ
Publication of JPH0278621A publication Critical patent/JPH0278621A/ja
Application granted granted Critical
Publication of JP2611003B2 publication Critical patent/JP2611003B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP1194406A 1988-07-29 1989-07-28 免疫促進剤 Expired - Lifetime JP2611003B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT21570A/88 1988-07-29
IT8821570A IT1227049B (it) 1988-07-29 1988-07-29 Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.

Publications (2)

Publication Number Publication Date
JPH0278621A JPH0278621A (ja) 1990-03-19
JP2611003B2 true JP2611003B2 (ja) 1997-05-21

Family

ID=11183757

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1194406A Expired - Lifetime JP2611003B2 (ja) 1988-07-29 1989-07-28 免疫促進剤

Country Status (7)

Country Link
EP (1) EP0352609B1 (https=)
JP (1) JP2611003B2 (https=)
AT (1) ATE84720T1 (https=)
DE (1) DE68904491T2 (https=)
ES (1) ES2053880T3 (https=)
GR (1) GR3006831T3 (https=)
IT (1) IT1227049B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807828A (en) * 1989-06-16 1998-09-15 Cor Therapeutics, Inc. Platelet aggregation inhibitors
IT1243859B (it) * 1990-10-23 1994-06-28 Bioresearch Spa Composizioni farmaceutiche comprendenti associazioni fra sali di s-adenosil-l-metionina e acido 5-metil (o 5-formil)-tetraidrofolico per la terapia di complicanze neurologiche negli ammalati di aids.
ES2259552B1 (es) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes.
WO2006097547A1 (es) * 2005-03-17 2006-09-21 Proyecto De Biomedicina Cima S.L. Empleo de 5'-metiltioadenosina (mta) en la prevención y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes
ES2329327B1 (es) 2008-03-19 2010-09-17 Proyecto De Biomedicina Cima, S.L. Combinaciones sinergicas de 5'-metiltioadenosina.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313937A1 (fr) * 1975-06-09 1977-01-07 Anvar Medicament a base de 5' thioethers de l'adenosine
FR2354100A2 (fr) * 1976-06-08 1978-01-06 Anvar Medicament a base de 5' thioethers de l'adenosine
IT1193529B (it) * 1980-04-22 1988-07-08 Bioresearch Srl Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo

Also Published As

Publication number Publication date
EP0352609B1 (en) 1993-01-20
DE68904491D1 (de) 1993-03-04
EP0352609A1 (en) 1990-01-31
DE68904491T2 (de) 1993-05-13
IT8821570A0 (it) 1988-07-29
GR3006831T3 (https=) 1993-06-30
ATE84720T1 (de) 1993-02-15
ES2053880T3 (es) 1994-08-01
IT1227049B (it) 1991-03-14
JPH0278621A (ja) 1990-03-19

Similar Documents

Publication Publication Date Title
Aoshima et al. Antitumor activities of newly synthesized N 4-acyl-1-β-D-arabinofuranosylcytosine
RU96105946A (ru) Способ сенсибилизации раковых клеток к лизису, опосредованному клетками-киллерами
WO1999029327A1 (en) Use of alpha-glucosidase inhibitors for treating high-risk impaired glucose tolerance
EP0672422A1 (en) Antiinflammatory and analgesic transdermal gel
WO2016188091A1 (zh) 烟酰胺单核苷酸在制备防治动脉硬化、心脑血管疾病的药物中的应用及其药物
JPH10505578A (ja) 全身性炎症および炎症性肝炎の処置のためのピリミジンヌクレオチド前駆体
CA2202397C (en) Compositions comprising carbonate/bicarbonate buffered dichloroacetic acid and methods for treatment of metabolic and cardiovascular disorders
SE465462B (sv) 6-brom-5-hydroxi-4-dimetylaminometyl-1-metyl-2-fenyltiometylindol-3-karbonsyra etylester-hydroklorid i monohydratform, foerfarande foer framstaellning av densamma och paa hydrokloriden i monohydratform baserat laekemedelspreparat med antivirusverkan interferoninducerande och immunomodulerande verkan
JP2611003B2 (ja) 免疫促進剤
EP0146363B1 (en) Synergistic pharmaceutical compositions, their production and use
AU750645B2 (en) Composition comprising L-carnitine or an alkanoyl L-carnitine and NADH and/or NADPH
JP2008533135A (ja) ゲムシタビン誘導体の経口投薬形態
JPH10158156A (ja) 抗腫瘍剤
JPS6328045B2 (https=)
KR20230136627A (ko) 포유 동물에서 체중 감소를 유도하기 위한 외인성 케톤 에스테르의 용도
AU2014203896B2 (en) Compositions and methods for treating cutaneous T cell lymphoma
JPS62263127A (ja) 自己由来のｌａｋ細胞、インタ−ロイキン−２、及びオルニチンデカルボキシラ−ゼ阻害剤による腫瘍の処置
WO2000038682A1 (en) Anti-hiv infection agents and method for treating hiv infection
JPH08268882A (ja) リパーゼ阻害剤
Wang et al. Recent studies on the immunopharmacology of a novel antibiotic Polyactin A
JPS58208223A (ja) 抗腫瘍剤
HK1219236A1 (zh) 氨基甲酸酯化合物在制备治疗猝倒的药物中的应用
HK1217165B (en) Compositions and methods for treating cutaneous t cell lymphoma
JPH0643306B2 (ja) 癌細胞転移抑制剤
JPH01163122A (ja) 抗レトロウイルス剤