ES2053880T3 - Utilizacion de derivados de adenosina en la preparacion de composiciones farmaceuticas que poseen actividad inmunoestimulante. - Google Patents
Utilizacion de derivados de adenosina en la preparacion de composiciones farmaceuticas que poseen actividad inmunoestimulante.Info
- Publication number
- ES2053880T3 ES2053880T3 ES89113194T ES89113194T ES2053880T3 ES 2053880 T3 ES2053880 T3 ES 2053880T3 ES 89113194 T ES89113194 T ES 89113194T ES 89113194 T ES89113194 T ES 89113194T ES 2053880 T3 ES2053880 T3 ES 2053880T3
- Authority
- ES
- Spain
- Prior art keywords
- radical
- adenosine derivatives
- immuno
- preparation
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003835 adenosine derivatives Chemical class 0.000 title abstract 3
- 230000003308 immunostimulating effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- -1 RADICAL PHENYL Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
EL USO DE DERIVADOS DE ADENOSINA EN PREPARACION DE COMPOSICIONES FARMACEUTICAS POSEYENDO ACTIVIDAD INMUNOESTIMULANTE, COMPRENDIENDO UN PORTADOR FARMACOLOGICAMENTE ACEPTABLE Y UNA CANTIDAD EFECTIVA DE AL MENOS UNO DE DICHOS DERIVADOS DE ADENOSINA DE FORMULA GENERAL (I): EN LA CUAL: R = C1-C18 RADICAL ALQUILO LINEAL O RAMIFICADO, O RADICAL FENILALQUILENO EN EL CUAL LA CADENA DE ALQUILENO TIENE DE 1 A 6 ATOMOS DE CARBONO. R1 = H, C1-C6 RADICAL ACILO ALIFATICO, O C7 RADICAL ACILO AROMATICO; R2 = H, C1-C6 RADICAL ACILO ALIFATICO, O C7 RADICAL ACILO AROMATICO, O LOS DOS RADICALES R2 A LA VEZ FORMAN UNA CADENA DE ISOPROPILIDINA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8821570A IT1227049B (it) | 1988-07-29 | 1988-07-29 | Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2053880T3 true ES2053880T3 (es) | 1994-08-01 |
Family
ID=11183757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES89113194T Expired - Lifetime ES2053880T3 (es) | 1988-07-29 | 1989-07-19 | Utilizacion de derivados de adenosina en la preparacion de composiciones farmaceuticas que poseen actividad inmunoestimulante. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0352609B1 (es) |
| JP (1) | JP2611003B2 (es) |
| AT (1) | ATE84720T1 (es) |
| DE (1) | DE68904491T2 (es) |
| ES (1) | ES2053880T3 (es) |
| GR (1) | GR3006831T3 (es) |
| IT (1) | IT1227049B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5795868A (en) * | 1989-06-16 | 1998-08-18 | Cor Therapeutics, Inc. | Platelet aggregation inhibitors |
| IT1243859B (it) * | 1990-10-23 | 1994-06-28 | Bioresearch Spa | Composizioni farmaceutiche comprendenti associazioni fra sali di s-adenosil-l-metionina e acido 5-metil (o 5-formil)-tetraidrofolico per la terapia di complicanze neurologiche negli ammalati di aids. |
| ES2259552B1 (es) * | 2005-03-17 | 2007-06-16 | Proyecto De Biomedicina Cima, S.L. | Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes. |
| HRP20090646T1 (hr) | 2005-03-17 | 2010-01-31 | Proyecto De Biomedicina Cima | Uporaba 5'-metiltioadenozina (mta) kod prevencije i/ili liječenja autoimunih bolesti i/ili odbacivanje transplantata |
| ES2329327B1 (es) | 2008-03-19 | 2010-09-17 | Proyecto De Biomedicina Cima, S.L. | Combinaciones sinergicas de 5'-metiltioadenosina. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2313937A1 (fr) * | 1975-06-09 | 1977-01-07 | Anvar | Medicament a base de 5' thioethers de l'adenosine |
| FR2354100A2 (fr) * | 1976-06-08 | 1978-01-06 | Anvar | Medicament a base de 5' thioethers de l'adenosine |
| IT1193529B (it) * | 1980-04-22 | 1988-07-08 | Bioresearch Srl | Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo |
-
1988
- 1988-07-29 IT IT8821570A patent/IT1227049B/it active
-
1989
- 1989-07-19 EP EP89113194A patent/EP0352609B1/en not_active Expired - Lifetime
- 1989-07-19 DE DE8989113194T patent/DE68904491T2/de not_active Expired - Fee Related
- 1989-07-19 ES ES89113194T patent/ES2053880T3/es not_active Expired - Lifetime
- 1989-07-19 AT AT89113194T patent/ATE84720T1/de not_active IP Right Cessation
- 1989-07-28 JP JP1194406A patent/JP2611003B2/ja not_active Expired - Lifetime
-
1993
- 1993-01-21 GR GR920403207T patent/GR3006831T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0352609B1 (en) | 1993-01-20 |
| JP2611003B2 (ja) | 1997-05-21 |
| DE68904491D1 (de) | 1993-03-04 |
| JPH0278621A (ja) | 1990-03-19 |
| ATE84720T1 (de) | 1993-02-15 |
| GR3006831T3 (es) | 1993-06-30 |
| DE68904491T2 (de) | 1993-05-13 |
| IT1227049B (it) | 1991-03-14 |
| IT8821570A0 (it) | 1988-07-29 |
| EP0352609A1 (en) | 1990-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI952680A0 (fi) | Injektoitavia taksaanijohdannaisiin pohjautuvia koostumuksia | |
| DK0585155T3 (da) | Trifluormethylketon-peptidderivater med HLE-inhiberende aktivitet, deres fremstilling og farmaceutiske præparater | |
| ES2051772T3 (es) | 2-sustituido-e-fusionado-(1,2,4)-triazol(1,5-c)pirimidinas, composiciones farmaceuticas y sus usos. | |
| ES2083668T5 (es) | Combinaciones antiviricas que contienen analogos de nucleosido. | |
| ES2150903T3 (es) | Derivados de 2-aralcoxi y 2-alcoxi adenosina de utilidad como vasodilatadores coronarios y como agentes antihipertensivos. | |
| ES2114931T3 (es) | Nuevos esteres esteroidales. | |
| AU583439B2 (en) | Prodrugs of rapamycin | |
| AR034858A1 (es) | Compuestos elevadores de abca-1,composicion farmaceutica y el uso de los mismos para la manufactura de un medicamento | |
| AR003143A1 (es) | Nuevos inhibidores de la farnesil transferasa, su preparacion y las composiciones farmaceuticas que los contienen. | |
| UY24386A1 (es) | Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen. | |
| ES2133410T3 (es) | Derivados sustituidos de la tiazolidindiona. | |
| CO4790173A1 (es) | Compuestos azo- y diazocicloheptano y -ciclooctano sustituidos | |
| ES2062395T3 (es) | Nuevos compuestos de bencimidazol y su uso. | |
| ES2157314T3 (es) | Derivados triciclicos y su uso en productos farmaceuticos. | |
| MX9204318A (es) | Complejos de derivados de pleuromutilina para su preparacion y composiciones farmaceuticas que los contienen. | |
| DK166323C (da) | Griseolsyrederivater og farmaceutiske midler indeholdende disse | |
| ES2119874T3 (es) | Nuevos derivados de elipticina, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
| CO5070654A1 (es) | Derivados de acidos fenilaminoalquilcarboxilicos y composiciones farmaceuticas que los comprenden | |
| ATE81004T1 (de) | Laktamimide in der behandlung arzneiresistenter protozoeninjektionen. | |
| ES2053880T3 (es) | Utilizacion de derivados de adenosina en la preparacion de composiciones farmaceuticas que poseen actividad inmunoestimulante. | |
| ES2053775T3 (es) | Derivados de tioformamida. | |
| BR0010381A (pt) | Método de tratamento da trombose em um mamìfero, e uso de uma combinação de (i) um inibidor do fator xa, e (ii) um composto selecionado do grupo que consiste em aspirina, tpa, um antagonista gpiib/iiia, heparina de baixo peso molecular e heparina | |
| AR002730A1 (es) | Derivados de 4alfa acetiloxi, 2alfa benzoiloxi, epoxi 5 beta, 20 hidroxi-1- beta-metilen-7beta,8beta oxo -9-aciloxi-10beta nor-19-taxen-11-il-13alfa,procedimiento para obtenerlos y composiciones farmaceuticas que incluyen dichos derivados. | |
| ES2060592T3 (es) | Un tioester y su uso en la preparacion de composiciones farmaceuticas para el tratamiento de los sindromes de isquemia y reperfusion. | |
| ES2054833T3 (es) | Derivados tioformamida. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 352609 Country of ref document: ES |