JP2563797B2 - ボルデテラ属細菌の蛋白質抗原の精製方法 - Google Patents

ボルデテラ属細菌の蛋白質抗原の精製方法

Info

Publication number
JP2563797B2
JP2563797B2 JP62092149A JP9214987A JP2563797B2 JP 2563797 B2 JP2563797 B2 JP 2563797B2 JP 62092149 A JP62092149 A JP 62092149A JP 9214987 A JP9214987 A JP 9214987A JP 2563797 B2 JP2563797 B2 JP 2563797B2
Authority
JP
Japan
Prior art keywords
buffer
solution
toxin
pertussis
carbonate buffer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP62092149A
Other languages
English (en)
Japanese (ja)
Other versions
JPS62258326A (ja
Inventor
クンタン−ミレ・マリー−ジヨゼ，ベ．
アルマンジヨン・フランソワ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PASUTSUURU MERIUU SEROMU E UAKUSAN
Original Assignee
PASUTSUURU MERIUU SEROMU E UAKUSAN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PASUTSUURU MERIUU SEROMU E UAKUSAN filed Critical PASUTSUURU MERIUU SEROMU E UAKUSAN
Publication of JPS62258326A publication Critical patent/JPS62258326A/ja
Application granted granted Critical
Publication of JP2563797B2 publication Critical patent/JP2563797B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
JP62092149A 1986-04-16 1987-04-16 ボルデテラ属細菌の蛋白質抗原の精製方法 Expired - Lifetime JP2563797B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8605456 1986-04-16
FR8605456A FR2597344B1 (fr) 1986-04-16 1986-04-16 Perfectionnement au procede de purification d'antigenes proteiques de bacteries appartenant au genre bordetella, en vue de l'obtention d'un vaccin acellulaire.

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP7333413A Division JP2599259B2 (ja) 1986-04-16 1995-12-21 ボルデテラ属細菌の蛋白質抗原の可溶化方法
JP7333415A Division JP2599260B2 (ja) 1986-04-16 1995-12-21 パータッシス毒素の無毒化方法

Publications (2)

Publication Number Publication Date
JPS62258326A JPS62258326A (ja) 1987-11-10
JP2563797B2 true JP2563797B2 (ja) 1996-12-18

Family

ID=9334300

Family Applications (3)

Application Number Title Priority Date Filing Date
JP62092149A Expired - Lifetime JP2563797B2 (ja) 1986-04-16 1987-04-16 ボルデテラ属細菌の蛋白質抗原の精製方法
JP7333415A Expired - Lifetime JP2599260B2 (ja) 1986-04-16 1995-12-21 パータッシス毒素の無毒化方法
JP7333413A Expired - Lifetime JP2599259B2 (ja) 1986-04-16 1995-12-21 ボルデテラ属細菌の蛋白質抗原の可溶化方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP7333415A Expired - Lifetime JP2599260B2 (ja) 1986-04-16 1995-12-21 パータッシス毒素の無毒化方法
JP7333413A Expired - Lifetime JP2599259B2 (ja) 1986-04-16 1995-12-21 ボルデテラ属細菌の蛋白質抗原の可溶化方法

Country Status (12)

Country Link
US (1) US4774086A (https=)
EP (1) EP0242301B1 (https=)
JP (3) JP2563797B2 (https=)
AT (1) ATE81782T1 (https=)
AU (1) AU601415B2 (https=)
CA (1) CA1328070C (https=)
DE (3) DE242301T1 (https=)
ES (1) ES2000435T3 (https=)
FR (1) FR2597344B1 (https=)
GR (2) GR880300043T1 (https=)
LU (1) LU90378I2 (https=)
ZA (1) ZA872712B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019027168A3 (ko) * 2017-08-01 2019-04-25 주식회사 녹십자 넁동 및 해동 과정을 포함하는 백일해균 유래 단백질 수득 방법

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT391080B (de) * 1986-06-24 1990-08-10 Immuno Ag Verfahren zur herstellung von gegen pseudomonas aeruginosa infektionen wirksamen praeparationen
US5237053A (en) * 1986-06-24 1993-08-17 Immuno Aktiengesellschaft Preparation active against Pseudomonas aeruginosa infections and methods of producing them
US5165927A (en) * 1986-08-01 1992-11-24 University Of Southern California Composition with modified pertussis toxin
US5032398A (en) * 1986-08-01 1991-07-16 Kaslow Harvey R Selective modification of the catalytic subunit of pertussis toxin
US4845036A (en) * 1987-02-03 1989-07-04 The United States Of America As Represented By The Department Of Health And Human Services Process for isolation of the B oligomer of pertussis toxin
JP2706792B2 (ja) * 1988-11-29 1998-01-28 財団法人化学及血清療法研究所 百日咳毒素のトキソイド化法
EP0484621A3 (en) * 1990-07-11 1992-08-26 American Cyanamid Company Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens
FR2672895B1 (fr) * 1991-02-15 1995-05-12 Transgene Sa Procede de purification d'une proteine fortement glycosylee.
US5445817A (en) * 1992-08-21 1995-08-29 The United States Of America As Represented By The Department Of Health And Human Services Pertussis toxin used as a carrier protein with non-charged saccharides in conjugate vaccines

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2047886A1 (en) * 1969-06-30 1971-03-19 Merieux Inst Non-toxic anti-whooping cough vaccine
US4247452A (en) * 1978-03-01 1981-01-27 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Purification of pertussis haemagglutinins
JPS5750925A (en) * 1980-09-12 1982-03-25 Takeda Chem Ind Ltd Preparation of pertussis toxoid
US4500639A (en) * 1981-10-15 1985-02-19 Teijin Limited Culturing Bordetella in media containing etherified cyclodextrin
CA1213234A (en) * 1983-03-30 1986-10-28 Akihiro Ginnaga Method for the production of ha fraction containing protective antigens of bordetella pertussis and pertussis vaccine
US4551429A (en) * 1983-09-15 1985-11-05 American Home Products Corporation Stimulation of antigen production by Bordetella pertussis
JPS6098988A (ja) * 1983-11-01 1985-06-01 Chemo Sero Therapeut Res Inst Ｌｐｆ−ｈａの精製法
JPS60237027A (ja) * 1984-05-07 1985-11-25 Chemo Sero Therapeut Res Inst 線維状赤血球凝集素の精製方法
CA1237998A (en) * 1984-04-14 1988-06-14 Akihiro Ginnaga Method for purification of filamentous hemagglutinin
GB8412207D0 (en) * 1984-05-12 1984-06-20 Wellcome Found Antigenic preparations
US4705686A (en) * 1986-05-09 1987-11-10 American Cyanamid Process for the preparation of acellular Bordetalla pertussis vaccine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019027168A3 (ko) * 2017-08-01 2019-04-25 주식회사 녹십자 넁동 및 해동 과정을 포함하는 백일해균 유래 단백질 수득 방법

Also Published As

Publication number Publication date
JP2599259B2 (ja) 1997-04-09
ES2000435A4 (es) 1988-03-01
DE19875021I2 (de) 2010-07-01
DE3782356D1 (de) 1992-12-03
EP0242301B1 (fr) 1992-10-28
ES2000435T3 (es) 1994-02-01
ZA872712B (en) 1987-10-05
EP0242301A1 (fr) 1987-10-21
GR880300043T1 (en) 1988-10-18
JPH08231421A (ja) 1996-09-10
AU601415B2 (en) 1990-09-13
FR2597344A1 (fr) 1987-10-23
DE3782356T2 (de) 1993-04-29
CA1328070C (fr) 1994-03-29
JP2599260B2 (ja) 1997-04-09
ATE81782T1 (de) 1992-11-15
LU90378I2 (fr) 1999-05-31
GR3006840T3 (https=) 1993-06-30
FR2597344B1 (fr) 1989-06-23
DE242301T1 (de) 1988-06-09
US4774086A (en) 1988-09-27
JPH08225463A (ja) 1996-09-03
AU7158187A (en) 1987-10-22
JPS62258326A (ja) 1987-11-10

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