JP2025524914A5 - - Google Patents

Info

Publication number
JP2025524914A5
JP2025524914A5 JP2025504039A JP2025504039A JP2025524914A5 JP 2025524914 A5 JP2025524914 A5 JP 2025524914A5 JP 2025504039 A JP2025504039 A JP 2025504039A JP 2025504039 A JP2025504039 A JP 2025504039A JP 2025524914 A5 JP2025524914 A5 JP 2025524914A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
acceptable salt
deuterated form
compound according
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025504039A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025524914A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/071162 external-priority patent/WO2024026433A2/en
Publication of JP2025524914A publication Critical patent/JP2025524914A/ja
Publication of JP2025524914A5 publication Critical patent/JP2025524914A5/ja
Pending legal-status Critical Current

Links

JP2025504039A 2022-07-28 2023-07-27 新規のdpp1阻害剤及びその使用 Pending JP2025524914A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202263369750P 2022-07-28 2022-07-28
US63/369,750 2022-07-28
US202363465517P 2023-05-10 2023-05-10
US63/465,517 2023-05-10
US202363468978P 2023-05-25 2023-05-25
US63/468,978 2023-05-25
PCT/US2023/071162 WO2024026433A2 (en) 2022-07-28 2023-07-27 Novel dpp1 inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
JP2025524914A JP2025524914A (ja) 2025-08-01
JP2025524914A5 true JP2025524914A5 (enExample) 2026-05-18

Family

ID=89707335

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025504039A Pending JP2025524914A (ja) 2022-07-28 2023-07-27 新規のdpp1阻害剤及びその使用

Country Status (4)

Country Link
US (1) US20260062420A1 (enExample)
EP (1) EP4561565A2 (enExample)
JP (1) JP2025524914A (enExample)
WO (1) WO2024026433A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2024009995A (es) * 2022-02-16 2024-08-22 Insmed Inc Determinadas n-(1-ciano-2-feniletil)-1,4-oxazepano-2-carboxamidas para el tratamiento de la hidrosadenitis supurativa.
EP4484423A4 (en) * 2022-02-22 2026-01-07 Haisco Pharmaceuticals Pte Ltd PROCESS FOR PREPARING A HETEROCYCLIC COMPOUND CONTAINING NITROGEN
CN115785083A (zh) * 2022-12-27 2023-03-14 瑞石生物医药有限公司 一种组织蛋白酶c小分子抑制剂及其制备方法
EP4646265A1 (en) 2023-01-06 2025-11-12 Insmed Incorporated Novel, reversible dpp1 inhibitors and uses thereof
WO2024173556A2 (en) * 2023-02-15 2024-08-22 Insmed Incorporated Uses of certain 1,4-oxazepane-2-carboxamides as dpp1 inhibitors
EP4680247A1 (en) * 2023-03-16 2026-01-21 Insmed Incorporated Dpp1 inhibitors with polycyclic linkers and uses thereof
WO2025056038A1 (en) * 2023-09-15 2025-03-20 Insmed Incorporated Dipeptidyl peptidase 1 inhibitors and uses thereof
WO2025162472A1 (en) * 2024-01-31 2025-08-07 Insmed Incorporated Linear dipeptidyl peptidase 1 inhibitors and uses thereof
WO2025167969A1 (en) * 2024-02-07 2025-08-14 Insmed Incorporated Dipeptidyl peptidase 1 inhibitors and uses thereof
WO2025214073A1 (en) * 2024-04-12 2025-10-16 Insmed Incorporated Dipeptidyl peptidase 1 inhibitors and uses thereof
WO2025250560A1 (en) * 2024-05-28 2025-12-04 Insmed Incorporated Methods for treating bronchiectasis
CN118666833B (zh) * 2024-05-30 2024-12-13 龙曦宁(上海)医药科技有限公司 一种2-(5-溴吡啶-3-基)奎宁环的制备方法
WO2026083346A1 (en) * 2024-10-18 2026-04-23 Insmed Incorporated Dpp1 inhibitors with cyclic or linear linkers and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100098683A (ko) * 2007-12-12 2010-09-08 아스트라제네카 아베 펩티딜 니트릴, 및 디펩티딜 펩티다제 i 억제제로서의 그의 용도
WO2011154677A1 (en) * 2010-06-09 2011-12-15 Astrazeneca Ab Substituted n-[1-cyano-2-(phenyl)ethyl] 1-aminocycloalk-1-ylcarboxamide compounds - 760

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