JP2025504859A5 - - Google Patents

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Publication number
JP2025504859A5
JP2025504859A5 JP2024543097A JP2024543097A JP2025504859A5 JP 2025504859 A5 JP2025504859 A5 JP 2025504859A5 JP 2024543097 A JP2024543097 A JP 2024543097A JP 2024543097 A JP2024543097 A JP 2024543097A JP 2025504859 A5 JP2025504859 A5 JP 2025504859A5
Authority
JP
Japan
Prior art keywords
disease
pharmaceutically acceptable
acceptable salt
syndrome
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024543097A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025504859A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2023/050504 external-priority patent/WO2023139534A1/en
Publication of JP2025504859A publication Critical patent/JP2025504859A/ja
Publication of JP2025504859A5 publication Critical patent/JP2025504859A5/ja
Pending legal-status Critical Current

Links

JP2024543097A 2022-01-24 2023-01-20 補体因子b阻害剤としてのスピロ環式ピペリジニル誘導体及びその使用 Pending JP2025504859A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263302246P 2022-01-24 2022-01-24
US63/302,246 2022-01-24
PCT/IB2023/050504 WO2023139534A1 (en) 2022-01-24 2023-01-20 Spirocyclic piperidinyl derivatives as complement factor b inhibitors and uses thereof

Publications (2)

Publication Number Publication Date
JP2025504859A JP2025504859A (ja) 2025-02-19
JP2025504859A5 true JP2025504859A5 (https=) 2026-01-27

Family

ID=85150566

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024543097A Pending JP2025504859A (ja) 2022-01-24 2023-01-20 補体因子b阻害剤としてのスピロ環式ピペリジニル誘導体及びその使用

Country Status (16)

Country Link
US (1) US20250115572A1 (https=)
EP (1) EP4469157A1 (https=)
JP (1) JP2025504859A (https=)
KR (1) KR20240138095A (https=)
CN (1) CN118696035A (https=)
AU (1) AU2023209631A1 (https=)
CA (1) CA3247772A1 (https=)
CL (1) CL2024002205A1 (https=)
CO (1) CO2024009660A2 (https=)
CR (1) CR20240300A (https=)
DO (1) DOP2024000142A (https=)
IL (1) IL314186A (https=)
JO (1) JOP20240165A1 (https=)
MX (1) MX2024009062A (https=)
PE (1) PE20242005A1 (https=)
WO (1) WO2023139534A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202334121A (zh) * 2021-10-27 2023-09-01 美商翰森生物有限責任公司 哌啶基吲哚衍生物、其製備方法及醫藥用途
TW202423426A (zh) * 2022-08-31 2024-06-16 美商奇努克醫療股份有限公司 經取代之吲哚化合物及其使用方法
IL320661A (en) * 2022-11-14 2025-07-01 Novartis Pharma Ag Solid forms of complement factor B inhibitors
TW202506657A (zh) * 2023-04-27 2025-02-16 大陸商上海翰森生物醫藥科技有限公司 一種哌啶基吲哚化合物的鹽及其製備方法
CN121889385A (zh) 2023-07-04 2026-04-17 希塔拉生物有限公司 作为因子b抑制剂的2-(1h-吲哚-4-基)甲基)2h-吲唑衍生物
IL325760A (en) 2023-07-04 2026-03-01 Sitala Bio Ltd History of 2-(1H-indol-4-yl)methyl)-isoindoline as factor B inhibitors
WO2025008516A2 (en) 2023-07-06 2025-01-09 Sitala Bio Ltd Novel compounds
WO2025008517A1 (en) 2023-07-06 2025-01-09 Sitala Bio Ltd Indole derivatives with factor b inhibitory activity
AU2024324780A1 (en) * 2023-08-16 2026-02-05 Inflarx Gmbh Fused piperidinyl bicyclic and related compounds for use in the treatment of diseases
WO2025172535A1 (en) 2024-02-15 2025-08-21 Sitala Bio Ltd Indole and benzimidazole compounds as factor b inhibitors
TW202543599A (zh) * 2024-03-08 2025-11-16 大陸商江蘇豪森藥業集團有限公司 一種多元螺環化合物的晶型、其製備方法和醫藥用途
WO2025256600A1 (zh) * 2024-06-12 2025-12-18 润尔眼科药物(广州)有限公司 一种杂环化合物及其用途
WO2026002007A1 (zh) * 2024-06-25 2026-01-02 珠海联邦制药股份有限公司 补体因子b抑制剂及其药物组合物和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007524596A (ja) 2003-02-28 2007-08-30 トランスフォーム・ファーマシューティカルズ・インコーポレイテッド 共結晶医薬組成物
JO3265B1 (ar) 2008-12-09 2018-09-16 Novartis Ag مثبطات بيريديلوكسى اندولات vegf-r2 واستخدامها لعلاج المرض
JO3425B1 (ar) 2013-07-15 2019-10-20 Novartis Ag مشتقات البابيريدينيل-اندول واستخدامها كعامل متمم لمثبطات b
RS66635B1 (sr) * 2017-08-31 2025-04-30 Novartis Ag Derivati piperidinil-indola za upotrebu u lečenju c3 glomerulopatije
KR20230049115A (ko) * 2020-08-07 2023-04-12 상하이 메이유에 바이오테크 디벨롭먼트 컴퍼니 리미티드 보체 인자 b 억제제 및 이의 약학적 조성물, 제조 방법 및 용도
CN120081822A (zh) * 2021-06-03 2025-06-03 诺瓦提斯药物公司 经取代的吲哚化合物及其使用方法
EP4389742A4 (en) * 2021-08-18 2026-01-14 Xizang Haisco Pharmaceutical Co Ltd HETEROAROMATIC CYCLE DERIVATIVE CONTAINING BENZO NITROGEN AND ITS USE IN MEDICINE
TW202334121A (zh) * 2021-10-27 2023-09-01 美商翰森生物有限責任公司 哌啶基吲哚衍生物、其製備方法及醫藥用途

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