JP2025503511A5 - - Google Patents

Info

Publication number
JP2025503511A5
JP2025503511A5 JP2024538652A JP2024538652A JP2025503511A5 JP 2025503511 A5 JP2025503511 A5 JP 2025503511A5 JP 2024538652 A JP2024538652 A JP 2024538652A JP 2024538652 A JP2024538652 A JP 2024538652A JP 2025503511 A5 JP2025503511 A5 JP 2025503511A5
Authority
JP
Japan
Prior art keywords
cancer
pharmaceutical product
product according
her2
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024538652A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025503511A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/062797 external-priority patent/WO2023126822A1/en
Publication of JP2025503511A publication Critical patent/JP2025503511A/ja
Publication of JP2025503511A5 publication Critical patent/JP2025503511A5/ja
Pending legal-status Critical Current

Links

JP2024538652A 2021-12-28 2022-12-27 抗体-薬物コンジュゲート及びrasg12c阻害剤の組み合わせ Pending JP2025503511A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163294367P 2021-12-28 2021-12-28
US63/294,367 2021-12-28
PCT/IB2022/062797 WO2023126822A1 (en) 2021-12-28 2022-12-27 Combination of antibody-drug conjugate and rasg12c inhibitor

Publications (2)

Publication Number Publication Date
JP2025503511A JP2025503511A (ja) 2025-02-04
JP2025503511A5 true JP2025503511A5 (https=) 2026-01-05

Family

ID=84943594

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024538652A Pending JP2025503511A (ja) 2021-12-28 2022-12-27 抗体-薬物コンジュゲート及びrasg12c阻害剤の組み合わせ

Country Status (6)

Country Link
US (1) US20250161305A1 (https=)
EP (1) EP4456899A1 (https=)
JP (1) JP2025503511A (https=)
CN (1) CN118434422A (https=)
TW (1) TW202333800A (https=)
WO (1) WO2023126822A1 (https=)

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
ATE198623T1 (de) 1994-08-12 2001-01-15 Myriad Genetics Inc Verfahren zum nachweis von prädisposition von ovarial- und brustkrebs
ATE201445T1 (de) 1994-08-12 2001-06-15 Myriad Genetics Inc Mutationen des mit 17q verbundenen ovarial- und brustkrebs empfindlichkeitsgens
DK1071700T3 (da) 1998-04-20 2010-06-07 Glycart Biotechnology Ag Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet
CA2704600C (en) 1999-04-09 2016-10-25 Kyowa Kirin Co., Ltd. A method for producing antibodies with increased adcc activity
CN100340575C (zh) 1999-06-25 2007-10-03 杰南技术公司 人源化抗ErbB2抗体及其在制备药物中的应用
CA2953239A1 (en) 2000-10-06 2002-04-18 Kyowa Hakko Kirin Co., Ltd. Antibody composition-producing cell
WO2007133855A2 (en) 2006-03-27 2007-11-22 University Of Maryland Biotechnology Institute Glycoprotein synthesis and remodeling by enzymatic transglycosylation
IN2014DN06806A (https=) 2012-02-10 2015-05-22 Univ Maryland
ES2773710T3 (es) 2012-10-11 2020-07-14 Daiichi Sankyo Co Ltd Enlazadores para conjugados de anticuerpo - fármaco
AU2014371934B2 (en) 2013-12-25 2020-01-23 Daiichi Sankyo Company, Limited Anti-TROP2 antibody-drug conjugate
IL310627B2 (en) 2014-01-31 2026-04-01 Daiichi Sankyo Co Ltd Anti-HER2 antibody-drug conjugates, compositions containing them and uses thereof
KR102445502B1 (ko) 2014-04-10 2022-09-21 다이이찌 산쿄 가부시키가이샤 항her3 항체-약물 콘주게이트
CN116059395A (zh) 2015-06-29 2023-05-05 第一三共株式会社 用于选择性制造抗体-药物缀合物的方法
TW202532104A (zh) 2017-05-15 2025-08-16 日商第一三共股份有限公司 抗體-藥物結合物及其用途
IL324591A (en) 2017-08-31 2026-01-01 Daiichi Sankyo Co Ltd Improved antibody-drug conjugate production methods
LT3710439T (lt) 2017-11-15 2023-05-10 Mirati Therapeutics, Inc. Kras g12c inhibitoriai
TW202012415A (zh) 2018-05-08 2020-04-01 瑞典商阿斯特捷利康公司 化學化合物
KR102934231B1 (ko) 2019-03-05 2026-03-06 아스트라제네카 아베 항암제로 유용한 융합 삼환식 화합물
PT3886991T (pt) 2019-12-11 2022-10-17 Lilly Co Eli Inibidores de kras g12c
JP7808058B2 (ja) 2020-06-02 2026-01-28 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング がんを治療するための縮合環化2-アミノ-3-シアノチオフェン及び誘導体

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