JP2023522229A5 - - Google Patents
Info
- Publication number
- JP2023522229A5 JP2023522229A5 JP2022563917A JP2022563917A JP2023522229A5 JP 2023522229 A5 JP2023522229 A5 JP 2023522229A5 JP 2022563917 A JP2022563917 A JP 2022563917A JP 2022563917 A JP2022563917 A JP 2022563917A JP 2023522229 A5 JP2023522229 A5 JP 2023522229A5
- Authority
- JP
- Japan
- Prior art keywords
- cdr
- amino acid
- acid sequence
- sequence
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010320420.3A CN113527486B (zh) | 2020-04-21 | 2020-04-21 | 一种抗Nectin-4的抗体及其应用 |
| CN202010320420.3 | 2020-04-21 | ||
| PCT/CN2021/088661 WO2021213434A1 (zh) | 2020-04-21 | 2021-04-21 | 一种抗Nectin-4的抗体及其应用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023522229A JP2023522229A (ja) | 2023-05-29 |
| JP2023522229A5 true JP2023522229A5 (https=) | 2024-05-01 |
| JP7813721B2 JP7813721B2 (ja) | 2026-02-13 |
Family
ID=78094041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022563917A Active JP7813721B2 (ja) | 2020-04-21 | 2021-04-21 | Ｎｅｃｔｉｎ－４に対する抗体及びその用途 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12590150B2 (https=) |
| EP (1) | EP4141029A4 (https=) |
| JP (1) | JP7813721B2 (https=) |
| KR (1) | KR20230007406A (https=) |
| CN (2) | CN113527486B (https=) |
| AU (1) | AU2021260639A1 (https=) |
| BR (1) | BR112022021322A2 (https=) |
| CA (1) | CA3176385A1 (https=) |
| MX (1) | MX2022013163A (https=) |
| WO (1) | WO2021213434A1 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4096717B1 (en) | 2020-01-31 | 2024-12-11 | Innate Pharma | Treatment of cancer |
| CN113527486B (zh) * | 2020-04-21 | 2025-12-02 | 迈威(上海)生物科技股份有限公司 | 一种抗Nectin-4的抗体及其应用 |
| US20230181749A1 (en) * | 2020-05-20 | 2023-06-15 | Bicycle TX Limited | Bicyclic peptide ligands specific for nectin-4 and uses thereof |
| MX2023005873A (es) * | 2020-11-25 | 2023-06-05 | Innate Pharma | Tratamiento del cancer. |
| CA3217112A1 (en) * | 2021-04-30 | 2022-11-03 | Wei Zhou | Antibody-drug conjugate targeting nectin-4 and preparation method therefor and use thereof |
| US20240366778A1 (en) * | 2021-08-27 | 2024-11-07 | Cspc Megalith Biopharmarceutical Co., Ltd. | Anti-nectin-4 antibody, drug conjugate, and preparation method therefor and use thereof |
| CN116478279A (zh) * | 2021-12-31 | 2023-07-25 | 武汉瑞法医疗器械有限公司 | 乙型肝炎病毒表面抗原纳米抗体吸附剂及制备方法和应用 |
| CN116063498A (zh) * | 2022-04-27 | 2023-05-05 | 博际生物医药科技(杭州)有限公司 | 单域抗Nectin-4抗体 |
| CN114702589B (zh) * | 2022-04-27 | 2022-11-01 | 博际生物医药科技(杭州)有限公司 | 治疗癌症的组合物和方法 |
| CN114702588B (zh) * | 2022-04-27 | 2022-11-22 | 博际生物医药科技(杭州)有限公司 | 抗Nectin-4抗体和双特异性抗体 |
| AU2023273063A1 (en) * | 2022-05-16 | 2024-11-14 | Jiangsu Hengrui Pharmaceuticals Co., Ltd. | Pharmaceutical composition containing anti-nectin-4 antibody drug conjugate and use thereof |
| CA3262070A1 (en) * | 2022-07-14 | 2025-06-13 | Bio-Thera Solutions, Ltd. | ANTI-NECTIN-4 ANTIBODIES AND THEIR USES |
| CN115368463B (zh) * | 2022-07-19 | 2025-12-19 | 合肥天港免疫药物有限公司 | 双特异性抗体及其应用 |
| EP4324849A1 (en) * | 2022-08-18 | 2024-02-21 | Emergence Therapeutics AG | Humanized anti-nectin-4 antibodies |
| CN120239708A (zh) * | 2022-09-20 | 2025-07-01 | 耐科廷疗法有限公司 | 针对黏连蛋白4的人源化抗体及其药物偶联物 |
| EP4609880A1 (en) * | 2022-10-28 | 2025-09-03 | Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd. | Preparation containing anti-nectin-4 antibody drug conjugate and use thereof |
| CN115877008A (zh) * | 2022-12-05 | 2023-03-31 | 中国科学院自动化研究所 | 用于膀胱癌检测的光学分子成像探针及其制备方法和应用 |
| JP2026508244A (ja) * | 2023-02-22 | 2026-03-10 | ナンジング リーズ バイオラブズ シーオー．， エルティーディー． | 抗Ｎｅｃｔｉｎ－４抗体及びそれを含む多重特異性抗体 |
| AU2024228349A1 (en) * | 2023-02-27 | 2025-09-11 | CSPC Megalith Biopharmaceutical Co., Ltd. | Pharmaceutical composition of recombinant humanized anti-nectin-4 monoclonal antibody-mmae conjugate drug |
| CN116381251B (zh) * | 2023-03-13 | 2024-06-25 | 柏定生物工程(北京)有限公司 | 一种肿瘤标志物诊断试剂盒及其诊断方法 |
| CN116589584B (zh) * | 2023-05-24 | 2025-02-14 | 深圳市先康达生命科学有限公司 | 靶向人Nectin4蛋白的抗体或其片段和应用 |
| WO2024251260A1 (zh) * | 2023-06-08 | 2024-12-12 | 江苏迈威康新药研发有限公司 | 结合Nectin-4的抗体及其用途 |
| CN119390781B (zh) * | 2023-08-04 | 2026-04-17 | 湖南中晟全肽生物科技股份有限公司 | 特异性结合Nectin-4的多肽及其用途 |
| EP4534101A1 (en) | 2023-10-02 | 2025-04-09 | Eli Lilly and Company | Antibody drug conjugate (adc) targeting nectin 4 and comprising an exatecan payload |
| TW202535960A (zh) * | 2024-01-08 | 2025-09-16 | 大陸商上海橙帆醫藥有限公司 | 抗體及其藥物偶聯物和用途 |
| CN117964682A (zh) * | 2024-01-12 | 2024-05-03 | 杭州爱科瑞思生物医药有限公司 | Dolastatin衍生物及其制备方法和应用 |
| CN120383674A (zh) * | 2024-01-26 | 2025-07-29 | 鲁南新时代生物技术有限公司 | 一种Nectin-4抗体及其应用 |
| WO2025162493A1 (zh) * | 2024-01-29 | 2025-08-07 | 甘李药业股份有限公司 | 抗Nectin-4抗体、配体药物偶联物及其应用 |
| WO2025195487A1 (zh) * | 2024-03-21 | 2025-09-25 | 石药集团巨石生物制药有限公司 | 靶向Nectin-4的抗体药物缀合物的用途 |
| CN117986367B (zh) * | 2024-04-02 | 2024-07-16 | 上海美迪西生物医药股份有限公司 | 靶点为Nectin-4的抗体及其应用 |
| WO2025222063A2 (en) * | 2024-04-17 | 2025-10-23 | Marengo Therapeutics, Inc. | Multifunctional molecules binding to tcr and uses thereof |
| KR20250177512A (ko) * | 2024-06-14 | 2025-12-24 | 삼성바이오에피스 주식회사 | 신규한 항-넥틴-4 항체 및 이의 용도 |
| WO2026008043A1 (zh) * | 2024-07-04 | 2026-01-08 | 石药集团巨石生物制药有限公司 | 靶向Nectin-4的抗体药物缀合物和免疫检查点抑制剂联合的用途 |
| WO2026057016A1 (en) * | 2024-09-12 | 2026-03-19 | LaNova Medicines Limited | Anti-nectin-4 antibodies and conjugates thereof |
| CN119930825A (zh) * | 2025-02-13 | 2025-05-06 | 哈尔滨医科大学 | 一种Nectin-4靶向的纳米抗体及其在制备治疗膀胱癌的产品中的应用 |
| CN120271712A (zh) * | 2025-04-18 | 2025-07-08 | 哈尔滨医科大学 | 靶向Nectin-4的纳米抗体及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080268476A1 (en) * | 2004-05-12 | 2008-10-30 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Nectin 4 (N4) as a Marker for Cancer Prognosis |
| JPWO2008044754A1 (ja) * | 2006-10-06 | 2010-02-18 | 武田薬品工業株式会社 | 癌の予防・治療剤 |
| WO2011112566A2 (en) * | 2010-03-11 | 2011-09-15 | Abbott Laboratories | Basigin binding proteins |
| EP3347048B1 (en) * | 2015-09-09 | 2020-04-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies having specificity to nectin-4 and uses thereof |
| BR112018074453A2 (pt) * | 2016-05-27 | 2019-03-19 | Abbvie Biotherapeutics Inc. | proteínas de ligação biespecíficas ligando uma protéina imunomoduladora e um antígeno tumoral |
| CN109810039B (zh) | 2017-11-22 | 2021-11-12 | 迈威(上海)生物科技股份有限公司 | 一种用于抗体-药物偶联的双取代马来酰胺类连接子及其制备方法和用途 |
| CN110392697A (zh) * | 2017-03-02 | 2019-10-29 | 国家医疗保健研究所 | 对nectin-4具有特异性的抗体及其用途 |
| WO2018226578A1 (en) | 2017-06-05 | 2018-12-13 | Agensys, Inc. | Nectin-4-binding proteins and methods of use thereof |
| KR102892725B1 (ko) * | 2018-05-09 | 2025-12-01 | 이슘 리서치 디벨롭먼트 컴퍼니 오브 더 히브루 유니버시티 오브 예루살렘 엘티디. | 인간 넥틴4에 특이적인 항체 |
| CN113527486B (zh) * | 2020-04-21 | 2025-12-02 | 迈威(上海)生物科技股份有限公司 | 一种抗Nectin-4的抗体及其应用 |
-
2020
- 2020-04-21 CN CN202010320420.3A patent/CN113527486B/zh active Active
-
2021
- 2021-04-21 WO PCT/CN2021/088661 patent/WO2021213434A1/zh not_active Ceased
- 2021-04-21 KR KR1020227040582A patent/KR20230007406A/ko active Pending
- 2021-04-21 BR BR112022021322A patent/BR112022021322A2/pt unknown
- 2021-04-21 EP EP21791797.0A patent/EP4141029A4/en active Pending
- 2021-04-21 CA CA3176385A patent/CA3176385A1/en active Pending
- 2021-04-21 JP JP2022563917A patent/JP7813721B2/ja active Active
- 2021-04-21 MX MX2022013163A patent/MX2022013163A/es unknown
- 2021-04-21 AU AU2021260639A patent/AU2021260639A1/en active Pending
- 2021-04-21 US US17/996,403 patent/US12590150B2/en active Active
- 2021-04-21 CN CN202180030277.7A patent/CN115427452B/zh active Active
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