JP2025509266A5 - - Google Patents

Info

Publication number
JP2025509266A5
JP2025509266A5 JP2024553327A JP2024553327A JP2025509266A5 JP 2025509266 A5 JP2025509266 A5 JP 2025509266A5 JP 2024553327 A JP2024553327 A JP 2024553327A JP 2024553327 A JP2024553327 A JP 2024553327A JP 2025509266 A5 JP2025509266 A5 JP 2025509266A5
Authority
JP
Japan
Prior art keywords
her2
cancer
antibody
targeted
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024553327A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025509266A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/063852 external-priority patent/WO2023172906A1/en
Publication of JP2025509266A publication Critical patent/JP2025509266A/ja
Publication of JP2025509266A5 publication Critical patent/JP2025509266A5/ja
Pending legal-status Critical Current

Links

JP2024553327A 2022-03-07 2023-03-07 Stingアゴニストを含む抗体薬物コンジュゲート、組み合わせ、および使用方法 Pending JP2025509266A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263317472P 2022-03-07 2022-03-07
US63/317,472 2022-03-07
US202263329680P 2022-04-11 2022-04-11
US63/329,680 2022-04-11
PCT/US2023/063852 WO2023172906A1 (en) 2022-03-07 2023-03-07 Antibody drug conjugates comprising sting agonists, combinations and methods of use

Publications (2)

Publication Number Publication Date
JP2025509266A JP2025509266A (ja) 2025-04-11
JP2025509266A5 true JP2025509266A5 (https=) 2026-03-13

Family

ID=85800735

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024553327A Pending JP2025509266A (ja) 2022-03-07 2023-03-07 Stingアゴニストを含む抗体薬物コンジュゲート、組み合わせ、および使用方法

Country Status (11)

Country Link
US (1) US20230398229A1 (https=)
EP (1) EP4489789A1 (https=)
JP (1) JP2025509266A (https=)
KR (1) KR20240150805A (https=)
CN (1) CN119173277A (https=)
AU (1) AU2023232820A1 (https=)
CA (1) CA3245425A1 (https=)
IL (1) IL315064A (https=)
MX (1) MX2024010916A (https=)
TW (1) TW202400241A (https=)
WO (1) WO2023172906A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL296901A (en) 2020-04-02 2022-12-01 Mersana Therapeutics Inc Antibody-drug conjugates comprising sting agonists
WO2024192017A1 (en) * 2023-03-13 2024-09-19 Mersana Therapeutics, Inc. Antibody drug conjugates comprising sting agonists, combinations and methods of use
WO2026043823A2 (en) * 2024-08-19 2026-02-26 Sutro Biopharma, Inc. Antibodies comprising site-specific non-natural amino acid residues, methods of preparation and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI695011B (zh) 2014-06-18 2020-06-01 美商梅爾莎納醫療公司 抗her2表位之單株抗體及其使用之方法
JP6991857B2 (ja) 2014-10-10 2022-01-13 イデラ ファーマシューティカルズ インコーポレイテッド Tlr9アゴニストをチェックポイント阻害剤と共に用いるがんの治療
US20180271996A1 (en) * 2017-02-28 2018-09-27 Mersana Therapeutics, Inc. Combination therapies of her2-targeted antibody-drug conjugates
EP4058024A1 (en) * 2019-11-15 2022-09-21 Seagen Inc. Methods of treating her2 positive breast cancer with tucatinib in combination with an anti-her2 antibody-drug conjugate
IL296901A (en) * 2020-04-02 2022-12-01 Mersana Therapeutics Inc Antibody-drug conjugates comprising sting agonists

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