JP2025503109A5 - - Google Patents

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Publication number
JP2025503109A5
JP2025503109A5 JP2024543463A JP2024543463A JP2025503109A5 JP 2025503109 A5 JP2025503109 A5 JP 2025503109A5 JP 2024543463 A JP2024543463 A JP 2024543463A JP 2024543463 A JP2024543463 A JP 2024543463A JP 2025503109 A5 JP2025503109 A5 JP 2025503109A5
Authority
JP
Japan
Prior art keywords
composition
tumor
antigen
associated antigen
binds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024543463A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025503109A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2023/051721 external-priority patent/WO2023139293A1/en
Publication of JP2025503109A publication Critical patent/JP2025503109A/ja
Publication of JP2025503109A5 publication Critical patent/JP2025503109A5/ja
Pending legal-status Critical Current

Links

JP2024543463A 2022-01-24 2023-01-24 サイトカインシグナル伝達経路の選択的な活性化のための組成物および方法 Pending JP2025503109A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263302514P 2022-01-24 2022-01-24
US63/302,514 2022-01-24
PCT/EP2023/051721 WO2023139293A1 (en) 2022-01-24 2023-01-24 Composition and methods for the selective activation of cytokine signaling pathways

Publications (2)

Publication Number Publication Date
JP2025503109A JP2025503109A (ja) 2025-01-30
JP2025503109A5 true JP2025503109A5 (enExample) 2026-01-22

Family

ID=85278300

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024543463A Pending JP2025503109A (ja) 2022-01-24 2023-01-24 サイトカインシグナル伝達経路の選択的な活性化のための組成物および方法

Country Status (8)

Country Link
US (1) US20230295348A1 (enExample)
EP (1) EP4469163A1 (enExample)
JP (1) JP2025503109A (enExample)
CN (1) CN118715024A (enExample)
AU (1) AU2023208426A1 (enExample)
CA (1) CA3248133A1 (enExample)
IL (1) IL314068A (enExample)
WO (1) WO2023139293A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL305828A (en) * 2021-03-22 2023-11-01 Novimmune Sa Bispecific antibodies targeting CD47 and PD-L1 and methods of using them
EP4493592A1 (en) 2022-03-14 2025-01-22 LamKap Bio gamma AG Bispecific gpc3xcd28 and gpc3xcd3 antibodies and their combination for targeted killing of gpc3 positive malignant cells
WO2026039791A1 (en) * 2024-08-16 2026-02-19 Regeneron Pharmaceuticals, Inc. Tumor-targeted split il2 receptor agonists

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US6172197B1 (en) 1991-07-10 2001-01-09 Medical Research Council Methods for producing members of specific binding pairs
PT1024191E (pt) 1991-12-02 2008-12-22 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
WO2006028936A2 (en) 2004-09-02 2006-03-16 Genentech, Inc. Heteromultimeric molecules
AU2006232287B2 (en) 2005-03-31 2011-10-06 Chugai Seiyaku Kabushiki Kaisha Methods for producing polypeptides by regulating polypeptide association
JP2006316040A (ja) 2005-05-13 2006-11-24 Genentech Inc Herceptin(登録商標)補助療法
DE102005028778A1 (de) 2005-06-22 2006-12-28 SUNJÜT Deutschland GmbH Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
JP2009541275A (ja) 2006-06-22 2009-11-26 ノボ・ノルデイスク・エー/エス 二重特異性抗体の生産
WO2010129304A2 (en) 2009-04-27 2010-11-11 Oncomed Pharmaceuticals, Inc. Method for making heteromultimeric molecules
HRP20241208T1 (hr) 2010-04-20 2024-11-22 Genmab A/S Heterodimerni proteini koji sadrže fc fragment protutijela i postupci za njihovu proizvodnju
CN103261220B (zh) 2010-08-16 2016-06-15 诺夫免疫股份有限公司 用于生成多特异性和多价抗体的方法
ES2758994T3 (es) 2010-11-05 2020-05-07 Zymeworks Inc Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc
BR112014010580B1 (pt) 2011-11-04 2021-01-12 Zymeworks, Inc. constructo de fc heteromultimérico isolado, composição, uso de um constructo de fc heteromultimérico isolado, composição de ácido nucléico e método para expressar o constructo de fc heteromultimérico isolado
UA117289C2 (uk) 2014-04-02 2018-07-10 Ф. Хоффманн-Ля Рош Аг Мультиспецифічне антитіло
PT3328894T (pt) 2015-08-06 2019-02-13 Agency Science Tech & Res Anticorpos de cadeia comum gama/il2rbeta
CN108290958B (zh) 2015-10-02 2021-12-28 豪夫迈·罗氏有限公司 多特异性抗体
GB201700345D0 (en) * 2017-01-09 2017-02-22 F-Star Beta Ltd Conditional agonists of immune responses
US11260117B2 (en) 2017-05-26 2022-03-01 Novimmune Sa Anti-CD47 x anti-mesothelin antibodies and methods of use thereof
JP2022511390A (ja) * 2018-11-20 2022-01-31 ユニバーシティ オブ ワシントン 分割インターロイキン模倣体およびその使用
EP3897851A2 (en) * 2018-12-17 2021-10-27 Revitope Limited Twin immune cell engager

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