JP2025179167A5 - - Google Patents
Info
- Publication number
- JP2025179167A5 JP2025179167A5 JP2025146248A JP2025146248A JP2025179167A5 JP 2025179167 A5 JP2025179167 A5 JP 2025179167A5 JP 2025146248 A JP2025146248 A JP 2025146248A JP 2025146248 A JP2025146248 A JP 2025146248A JP 2025179167 A5 JP2025179167 A5 JP 2025179167A5
- Authority
- JP
- Japan
- Prior art keywords
- sodium
- dodecanoyl
- decanoyl
- capric
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18166177.8 | 2018-04-06 | ||
| EP18166177 | 2018-04-06 | ||
| EP18211296.1 | 2018-12-10 | ||
| EP18211296 | 2018-12-10 | ||
| PCT/EP2019/058828 WO2019193204A1 (en) | 2018-04-06 | 2019-04-08 | Pharmaceutical compositions for the transmucosal delivery of therapeutic peptides and proteins |
| JP2020554523A JP7442823B2 (ja) | 2018-04-06 | 2019-04-08 | 治療用ペプチド及び治療用タンパク質の経粘膜送達のための薬学的組成物 |
| JP2024020483A JP7744049B2 (ja) | 2018-04-06 | 2024-02-14 | 治療用ペプチド及び治療用タンパク質の経粘膜送達のための薬学的組成物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024020483A Division JP7744049B2 (ja) | 2018-04-06 | 2024-02-14 | 治療用ペプチド及び治療用タンパク質の経粘膜送達のための薬学的組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025179167A JP2025179167A (ja) | 2025-12-09 |
| JP2025179167A5 true JP2025179167A5 (https=) | 2026-03-13 |
Family
ID=66182513
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020554523A Active JP7442823B2 (ja) | 2018-04-06 | 2019-04-08 | 治療用ペプチド及び治療用タンパク質の経粘膜送達のための薬学的組成物 |
| JP2024020483A Active JP7744049B2 (ja) | 2018-04-06 | 2024-02-14 | 治療用ペプチド及び治療用タンパク質の経粘膜送達のための薬学的組成物 |
| JP2025146248A Pending JP2025179167A (ja) | 2018-04-06 | 2025-09-03 | 治療用ペプチド及び治療用タンパク質の経粘膜送達のための薬学的組成物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020554523A Active JP7442823B2 (ja) | 2018-04-06 | 2019-04-08 | 治療用ペプチド及び治療用タンパク質の経粘膜送達のための薬学的組成物 |
| JP2024020483A Active JP7744049B2 (ja) | 2018-04-06 | 2024-02-14 | 治療用ペプチド及び治療用タンパク質の経粘膜送達のための薬学的組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20210087250A1 (https=) |
| EP (1) | EP3773475A1 (https=) |
| JP (3) | JP7442823B2 (https=) |
| WO (1) | WO2019193204A1 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20211081T1 (hr) | 2015-09-15 | 2021-10-15 | Scholar Rock, Inc. | Anti-pro/latentna miostatinska protutijela i njihove uporabe |
| WO2020127476A1 (en) | 2018-12-19 | 2020-06-25 | Krka, D.D., Novo Mesto | Pharmaceutical composition comprising glp-1 analogue |
| CN120241997A (zh) | 2019-02-18 | 2025-07-04 | 伊莱利利公司 | 治疗性抗体制剂 |
| WO2020180534A1 (en) | 2019-03-01 | 2020-09-10 | President And Fellows Of Harvard College | Methods and compositions for protein delivery |
| MX2022001975A (es) | 2019-08-16 | 2022-03-11 | Applied Molecular Transport Inc | Composiciones, formulaciones y produccion y purificacion de interleucinas. |
| WO2021123228A1 (en) | 2019-12-18 | 2021-06-24 | Krka, D.D., Novo Mesto | Pharmaceutical composition comprising glp-1 analogue |
| WO2021142737A1 (en) * | 2020-01-16 | 2021-07-22 | Shanghai Benemae Pharmaceutical Corporation | Compositions and methods for treating non-alcoholic steatohepatitis (nash) |
| WO2021142733A1 (en) * | 2020-01-16 | 2021-07-22 | Shanghai Benemae Pharmaceutical Corporation | Combinational therapy comprising glp-1 and/or glp-1 analogs, and insulin and/or insulin analogs |
| CN115397455A (zh) * | 2020-01-16 | 2022-11-25 | 上海仁会生物制药股份有限公司 | Glp-1给药方案 |
| CA3221555A1 (en) * | 2021-06-23 | 2022-12-29 | Kimberly LONG | A myostatin pathway inhibitor in combination with a glp-1 pathway activator for use in treating metabolic disorders |
| KR20230000682A (ko) * | 2021-06-25 | 2023-01-03 | 한미약품 주식회사 | 심혈관 질환 또는 신장 기능장애 발생의 위험을 감소시키기 위한 에페글레나타이드 |
| AU2022386166A1 (en) | 2021-11-10 | 2024-06-20 | I2O Therapeutics, Inc. | Ionic liquid compositions |
| EP4180060A1 (en) * | 2021-11-15 | 2023-05-17 | Adocia | Solid compositions comprising a peptide or a protein and an acylated amino acid |
| EP4299057A1 (en) * | 2022-06-30 | 2024-01-03 | Adocia | Solid compositions comprising a peptide or a protein and an acylated amino acid |
| CN118234742A (zh) * | 2021-12-01 | 2024-06-21 | 江苏恒瑞医药股份有限公司 | Glp-1和gip受体双重激动剂的药物组合物及其用途 |
| EP4226918A1 (en) * | 2022-02-15 | 2023-08-16 | Filip Majewski | Pharmaceutical single dosage form for oral delivery of peptides |
| CN114544812B (zh) * | 2022-02-18 | 2023-06-30 | 复旦大学附属中山医院 | 一种代谢组合式标志物在诊断哮喘中的应用 |
| WO2023174433A1 (en) * | 2022-03-18 | 2023-09-21 | Smart Pharmaceutical (Suzhou) Co., Ltd. | Solid, semisolid, or liquid compositions for augmenting the stability, permeability and bioavailability of active pharmaceutical substances |
| CN120129529A (zh) * | 2022-04-29 | 2025-06-10 | 鹏跃医药科技有限公司 | 用于鼻內給药的索马鲁肽及其盐的药物組合物 |
| WO2024051787A1 (zh) * | 2022-09-09 | 2024-03-14 | 北京惠之衡生物科技有限公司 | 一种长效酰化胰岛素衍生物及其应用 |
| CN115590826B (zh) * | 2022-10-21 | 2023-12-19 | 北京安必奇生物科技有限公司 | 一种活性蛋白黏膜给药制剂及其制备方法和应用 |
| CN115656391B (zh) * | 2022-12-12 | 2023-04-07 | 哈尔滨吉象隆生物技术有限公司 | 一种特立帕肽含有的杂质的检测方法 |
| EP4638496A1 (en) | 2022-12-22 | 2025-10-29 | Scholar Rock, Inc. | Selective and potent inhibitory antibodies of myostatin activation |
| CN116407641A (zh) * | 2023-01-12 | 2023-07-11 | 深圳奥礼生物科技有限公司 | 多肽稳定剂和药物组合物 |
| TW202444407A (zh) * | 2023-03-23 | 2024-11-16 | 奧孟亞股份有限公司 | 一種高生物利用度之口服glp促效劑藥物組合物 |
| TW202440149A (zh) * | 2023-03-23 | 2024-10-16 | 奧孟亞股份有限公司 | 口服glp促效劑之藥物組合物 |
| WO2025014889A2 (en) * | 2023-07-07 | 2025-01-16 | Procompounding, Llc | Semaglutide formulations |
| WO2025037993A1 (en) | 2023-08-13 | 2025-02-20 | Filip Majewski | Dosage form for peptide agents |
| US20250221990A1 (en) * | 2023-08-21 | 2025-07-10 | Cmpd Licensing, Llc | Topical administration to the oral cavity |
| US12589135B2 (en) * | 2023-08-21 | 2026-03-31 | Cmpd Licensing, Llc | Topical administration of GLP-1 receptor agonists |
| CN119454605B (zh) * | 2023-11-30 | 2025-12-19 | 深圳奥礼生物科技有限公司 | 一种实现多肽口服吸收的组合物 |
| WO2025113170A1 (zh) * | 2023-12-01 | 2025-06-05 | 中山万汉制药有限公司 | 含有glp-1受体激动剂的经鼻给药的组合物及其制备方法与用途 |
| WO2025166413A1 (en) * | 2024-02-05 | 2025-08-14 | Ix Biopharma Limited | Compositions and methods for delivering glp-1 agonists (metabolix) |
| WO2025251740A1 (en) * | 2024-06-03 | 2025-12-11 | Shenzhen Oralead Pharma Co., LTD. | Oral polypeptide composition |
| CN119454909B (zh) * | 2025-01-13 | 2025-04-08 | 上海世领制药有限公司 | 经鼻粘膜给药的胰高血糖素样肽-1受体激动剂的制剂组合物、制备方法、用途及鼻施用器 |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3219656A (en) | 1963-08-12 | 1965-11-23 | Rohm & Haas | Alkylpolyalkoxyalkyl glucosides and process of preparation therefor |
| US3839318A (en) | 1970-09-27 | 1974-10-01 | Rohm & Haas | Process for preparation of alkyl glucosides and alkyl oligosaccharides |
| JPS57144214A (en) * | 1981-03-03 | 1982-09-06 | Kyoto Yakuhin Kogyo Kk | Pharmaceutical preparation for rectum medication |
| AT382381B (de) | 1984-10-02 | 1987-02-25 | Oesterr Zuckerfab Evidenz | Verfahren zur herstellung neuer grenzfl|chenaktiver kohlenhydrat-derivate |
| DK39892D0 (da) | 1992-03-25 | 1992-03-25 | Bernard Thorens | Peptid |
| US5661130A (en) | 1993-06-24 | 1997-08-26 | The Uab Research Foundation | Absorption enhancers for drug administration |
| US5869602A (en) | 1995-03-17 | 1999-02-09 | Novo Nordisk A/S | Peptide derivatives |
| US5866536A (en) | 1995-03-31 | 1999-02-02 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| JPH09208485A (ja) * | 1996-01-31 | 1997-08-12 | Teijin Ltd | ペプチド・蛋白質性薬物の水難溶性組成物 |
| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| US5773647A (en) | 1997-02-07 | 1998-06-30 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| EP1049486A4 (en) * | 1997-12-05 | 2006-01-04 | Lilly Co Eli | GLP-1 FORMULATIONS |
| WO1999043706A1 (en) | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | Derivatives of glp-1 analogs |
| JP2003522099A (ja) | 1998-02-27 | 2003-07-22 | ノボ ノルディスク アクティーゼルスカブ | 遅延作用プロファイルを有するｇｌｐ−１のｇｌｐ−１誘導体及びエキセンジン |
| JP2002506792A (ja) | 1998-02-27 | 2002-03-05 | ノボ ノルディスク アクティーゼルスカブ | Ｎ末端修飾ｇｌｐ−１誘導体 |
| EP1061946B1 (en) | 1998-02-27 | 2004-04-28 | Novo Nordisk A/S | Glp-1 derivatives with helix-content exceeding 25 %, forming partially structured micellar-like aggregates |
| ES2235854T3 (es) | 1999-04-05 | 2005-07-16 | Emisphere Technologies, Inc. | Sales disodicas, monohidratos y solvatos etanolicos para aportar agentes activos. |
| US20030017195A1 (en) | 2001-07-20 | 2003-01-23 | Samir Mitragotri | Method for oral drug delivery |
| JP3634340B2 (ja) * | 2002-11-29 | 2005-03-30 | フロイント産業株式会社 | 水性セラック皮膜剤とその製造方法及び該皮膜剤を用いたコーティング食品とその製造方法並びにコーティング医薬品とその製造方法 |
| BR122019021416A2 (https=) | 2003-09-19 | 2019-12-21 | ||
| ATE461217T1 (de) | 2003-12-18 | 2010-04-15 | Novo Nordisk As | Glp-1-verbindungen |
| EP1696962A2 (en) | 2003-12-18 | 2006-09-06 | Novo Nordisk A/S | Novel glp-1 analogues linked to albumin-like agents |
| US7279457B2 (en) * | 2004-03-12 | 2007-10-09 | Biodel, Inc. | Rapid acting drug delivery compositions |
| US20080085298A1 (en) * | 2004-03-12 | 2008-04-10 | Biodel, Inc. | Rapid Mucosal Gel or Film Insulin Compositions |
| ES2527286T3 (es) * | 2004-04-30 | 2015-01-22 | Abraxis Bioscience, Llc | Microesferas de liberación sostenida y métodos de fabricación y uso de las mismas |
| CA2572770A1 (en) | 2004-07-08 | 2006-01-19 | Novo-Nordisk A/S | Polypeptide protracting tags comprising a tetrazole moiety |
| US20060046962A1 (en) | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
| US8030273B2 (en) | 2004-10-07 | 2011-10-04 | Novo Nordisk A/S | Protracted exendin-4 compounds |
| WO2006037810A2 (en) | 2004-10-07 | 2006-04-13 | Novo Nordisk A/S | Protracted glp-1 compounds |
| TWI362392B (en) | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| US8603972B2 (en) | 2005-03-18 | 2013-12-10 | Novo Nordisk A/S | Extended GLP-1 compounds |
| WO2008023050A1 (en) | 2006-08-25 | 2008-02-28 | Novo Nordisk A/S | Acylated exendin-4 compounds |
| US8377863B2 (en) * | 2007-05-29 | 2013-02-19 | Unigene Laboratories Inc. | Peptide pharmaceutical for oral delivery |
| EP2190872B1 (en) | 2007-09-05 | 2018-03-14 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
| WO2009030771A1 (en) | 2007-09-05 | 2009-03-12 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
| US20100292133A1 (en) | 2007-09-05 | 2010-11-18 | Novo Nordisk A/S | Truncated glp-1 derivaties and their therapeutical use |
| RU2548807C2 (ru) | 2009-05-20 | 2015-04-20 | Торэй Индастриз, Инк. | Пептиды, проникающие в клетку |
| JP6016234B2 (ja) | 2009-09-30 | 2016-10-26 | ティオマトリックス・フォルシュンクス・ウント・べラートゥンクス・ゲーエムベーハー | ビタミンｂ部分構造を持つ粘膜付着性ポリマー |
| CN102970864A (zh) | 2010-04-21 | 2013-03-13 | 那挪玛加医药有限公司 | 纳米颗粒药物组合物 |
| CN103347532A (zh) | 2011-02-04 | 2013-10-09 | 爱奇司治疗公司 | 口服可生物利用肽药物组合物及其方法 |
| CN102120781B (zh) * | 2011-03-16 | 2013-07-17 | 中国药科大学 | 一种新型胰岛素口服纳米粒的制备及应用 |
| EP2696847A1 (en) | 2011-04-14 | 2014-02-19 | Novo Nordisk A/S | Fatty acid acylated amino acids for oral peptide delivery |
| HRP20181447T1 (hr) | 2012-03-22 | 2018-11-02 | Novo Nordisk A/S | Pripravci glp-1 peptida i njihova priprava |
| IN2014MN02304A (https=) | 2012-05-03 | 2015-08-07 | Zealand Pharma As | |
| US20150174076A1 (en) | 2012-06-14 | 2015-06-25 | Entrega, Inc. | Mucoadhesive devices for delivery of active agents |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| WO2015086728A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| US10570184B2 (en) | 2014-06-04 | 2020-02-25 | Novo Nordisk A/S | GLP-1/glucagon receptor co-agonists for medical use |
| JP2018529749A (ja) * | 2015-10-07 | 2018-10-11 | シプルメット・ゲーエムベーハー | ペプチド薬物を経口送達するための医薬製剤 |
| JPWO2017183559A1 (ja) * | 2016-04-19 | 2019-02-21 | 学校法人神戸学院 | 薬物の経粘膜吸収促進剤 |
-
2019
- 2019-04-08 WO PCT/EP2019/058828 patent/WO2019193204A1/en not_active Ceased
- 2019-04-08 EP EP19717801.5A patent/EP3773475A1/en active Pending
- 2019-04-08 JP JP2020554523A patent/JP7442823B2/ja active Active
- 2019-04-08 US US17/045,535 patent/US20210087250A1/en active Pending
-
2024
- 2024-02-14 JP JP2024020483A patent/JP7744049B2/ja active Active
-
2025
- 2025-09-03 JP JP2025146248A patent/JP2025179167A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025179167A5 (https=) | ||
| JP2021520391A5 (https=) | ||
| JP2017531665A5 (https=) | ||
| RU2017115651A (ru) | Фармацевтические составы для пероральной доставки пептидных или белковых лекарственных средств | |
| ES2229203T3 (es) | Composicion farmaceutica que contiene un polipeptido activo fisiologicamente. | |
| RU2472492C2 (ru) | Стабильные неводные фармацевтические композиции | |
| RU2327484C2 (ru) | Фармацевтическая композиция для назального всасывания | |
| JP2018529749A5 (https=) | ||
| Pontiroli | Peptide hormones: review of current and emerging uses by nasal delivery | |
| JP2010529956A5 (https=) | ||
| WO2018065634A1 (en) | Pharmaceutical compositions for the nasal delivery of peptide or protein drugs | |
| WO2023066293A1 (en) | Oral delivery of therapeutic agents | |
| JP5892940B2 (ja) | クラウン化合物及び／又は対イオンと複合体化されたペプチドを含む粘膜送達組成物 | |
| WO2025112258A1 (zh) | 一种实现多肽口服吸收的组合物 | |
| WO2023095944A1 (en) | Ultra long acting pharmaceutical composition comprising insulin | |
| EP4292583A1 (en) | Composition in which absorbability of poorly-absorbable drug is improved | |
| EP4631514A1 (en) | Oral polypeptide composition and use thereof | |
| JPS63243033A (ja) | 経鼻投与組成物 | |
| NZ760995B2 (en) | Pharmaceutical compositions for delivery of peptide | |
| NZ760995A (en) | Pharmaceutical compositions for delivery of peptide |