JP2025063045A5 - - Google Patents

Info

Publication number
JP2025063045A5
JP2025063045A5 JP2024221659A JP2024221659A JP2025063045A5 JP 2025063045 A5 JP2025063045 A5 JP 2025063045A5 JP 2024221659 A JP2024221659 A JP 2024221659A JP 2024221659 A JP2024221659 A JP 2024221659A JP 2025063045 A5 JP2025063045 A5 JP 2025063045A5
Authority
JP
Japan
Prior art keywords
hydrogel
alkyl
independently
linker
heteroaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024221659A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025063045A (ja
Filing date
Publication date
Priority claimed from PCT/US2020/029911 external-priority patent/WO2020219943A1/en
Application filed filed Critical
Publication of JP2025063045A publication Critical patent/JP2025063045A/ja
Publication of JP2025063045A5 publication Critical patent/JP2025063045A5/ja
Pending legal-status Critical Current

Links

JP2024221659A 2019-04-26 2024-12-18 徐放性サイトカインコンジュゲート Pending JP2025063045A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962839112P 2019-04-26 2019-04-26
US62/839,112 2019-04-26
PCT/US2020/029911 WO2020219943A1 (en) 2019-04-26 2020-04-24 Slow-release cytokine conjugates
JP2021563306A JP7608360B2 (ja) 2019-04-26 2020-04-24 徐放性サイトカインコンジュゲート

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021563306A Division JP7608360B2 (ja) 2019-04-26 2020-04-24 徐放性サイトカインコンジュゲート

Publications (2)

Publication Number Publication Date
JP2025063045A JP2025063045A (ja) 2025-04-15
JP2025063045A5 true JP2025063045A5 (https=) 2025-08-19

Family

ID=72941771

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021563306A Active JP7608360B2 (ja) 2019-04-26 2020-04-24 徐放性サイトカインコンジュゲート
JP2024221659A Pending JP2025063045A (ja) 2019-04-26 2024-12-18 徐放性サイトカインコンジュゲート

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021563306A Active JP7608360B2 (ja) 2019-04-26 2020-04-24 徐放性サイトカインコンジュゲート

Country Status (11)

Country Link
US (1) US20220193253A1 (https=)
EP (1) EP3958888A4 (https=)
JP (2) JP7608360B2 (https=)
KR (1) KR20220004134A (https=)
CN (1) CN114126638A (https=)
AU (1) AU2020261076B2 (https=)
BR (1) BR112021021481A2 (https=)
CA (1) CA3136726A1 (https=)
MX (1) MX2021012813A (https=)
SG (1) SG11202111175YA (https=)
WO (1) WO2020219943A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019028419A1 (en) 2017-08-03 2019-02-07 Synthorx, Inc. CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES
ES3059360T3 (en) 2018-11-08 2026-03-19 Synthorx Inc Interleukin 10 conjugates and uses thereof
KR20260039812A (ko) 2019-02-06 2026-03-20 신톡스, 인크. Il-2 콘쥬게이트 및 이의 사용 방법
CN114555632A (zh) 2019-08-23 2022-05-27 新索思股份有限公司 Il-15缀合物及其用途
MX2022002740A (es) 2019-09-10 2022-03-25 Synthorx Inc Conjugados de il-2 y metodos de uso para tratar enfermedades autoinmunes.
CA3153644A1 (en) * 2019-09-30 2021-04-08 Beijing Xuanyi Pharmasciences Co., Ltd. Protein-macromolecule conjugates and methods of use thereof
WO2022115563A1 (en) * 2020-11-25 2022-06-02 Prolynx Llc Extended release hydrogel conjugates of c-natriuretic peptides
AU2022249281B2 (en) * 2021-03-29 2025-08-14 Aj Sciences (Yixing) Co., Ltd Protein-macromolecule conjugates and methods of use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7052686B2 (en) * 2000-09-29 2006-05-30 Schering Corporation Pegylated interleukin-10
MXPA06014465A (es) * 2004-06-10 2007-05-16 Zymogenetics Inc Zcytor14 soluble, anticuerpos anti-zcytor14 y moleculas de union y metodos de uso en inflamacion.
EP2566335B1 (en) * 2010-05-05 2016-06-29 Prolynx Llc Controlled release of active compounds from macromolecular conjugates
EP2566334B1 (en) 2010-05-05 2018-04-18 Prolynx, LLC Controlled drug release from solid supports
US8703907B2 (en) * 2010-05-05 2014-04-22 Prolynx Llc Controlled drug release from dendrimers
KR102109067B1 (ko) * 2011-09-07 2020-05-13 프로린크스 엘엘시 생분해성 교차결합을 가지는 하이드로젤
DK2986312T3 (da) 2013-04-19 2022-02-14 Cytune Pharma Cytokinafledt behandling med reduceret vaskulært lækagesyndrom
MA39711A (fr) 2014-04-03 2015-10-08 Nektar Therapeutics Conjugués d'une fraction d'il-15 et d'un polymère
WO2016025385A1 (en) 2014-08-11 2016-02-18 Delinia, Inc. Modified il-2 variants that selectively activate regulatory t cells for the treatment of autoimmune diseases
US20180360977A1 (en) * 2015-12-21 2018-12-20 Armo Biosciences, Inc. Interleukin-15 Compositions and Uses Thereof
WO2019028419A1 (en) * 2017-08-03 2019-02-07 Synthorx, Inc. CYTOKINE CONJUGATES FOR THE TREATMENT OF PROLIFERATIVE AND INFECTIOUS DISEASES

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