JP2025063045A5 - - Google Patents

Info

Publication number
JP2025063045A5
JP2025063045A5 JP2024221659A JP2024221659A JP2025063045A5 JP 2025063045 A5 JP2025063045 A5 JP 2025063045A5 JP 2024221659 A JP2024221659 A JP 2024221659A JP 2024221659 A JP2024221659 A JP 2024221659A JP 2025063045 A5 JP2025063045 A5 JP 2025063045A5
Authority
JP
Japan
Prior art keywords
hydrogel
alkyl
independently
linker
heteroaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024221659A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025063045A (ja
Filing date
Publication date
Priority claimed from JP2021563306A external-priority patent/JP7608360B2/ja
Application filed filed Critical
Publication of JP2025063045A publication Critical patent/JP2025063045A/ja
Publication of JP2025063045A5 publication Critical patent/JP2025063045A5/ja
Pending legal-status Critical Current

Links

JP2024221659A 2019-04-26 2024-12-18 徐放性サイトカインコンジュゲート Pending JP2025063045A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962839112P 2019-04-26 2019-04-26
US62/839,112 2019-04-26
JP2021563306A JP7608360B2 (ja) 2019-04-26 2020-04-24 徐放性サイトカインコンジュゲート
PCT/US2020/029911 WO2020219943A1 (en) 2019-04-26 2020-04-24 Slow-release cytokine conjugates

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021563306A Division JP7608360B2 (ja) 2019-04-26 2020-04-24 徐放性サイトカインコンジュゲート

Publications (2)

Publication Number Publication Date
JP2025063045A JP2025063045A (ja) 2025-04-15
JP2025063045A5 true JP2025063045A5 (https=) 2025-08-19

Family

ID=72941771

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021563306A Active JP7608360B2 (ja) 2019-04-26 2020-04-24 徐放性サイトカインコンジュゲート
JP2024221659A Pending JP2025063045A (ja) 2019-04-26 2024-12-18 徐放性サイトカインコンジュゲート

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021563306A Active JP7608360B2 (ja) 2019-04-26 2020-04-24 徐放性サイトカインコンジュゲート

Country Status (11)

Country Link
US (1) US20220193253A1 (https=)
EP (1) EP3958888A4 (https=)
JP (2) JP7608360B2 (https=)
KR (1) KR20220004134A (https=)
CN (1) CN114126638A (https=)
AU (1) AU2020261076B2 (https=)
BR (1) BR112021021481A2 (https=)
CA (1) CA3136726A1 (https=)
MX (1) MX2021012813A (https=)
SG (1) SG11202111175YA (https=)
WO (1) WO2020219943A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240141853A (ko) 2017-08-03 2024-09-27 신톡스, 인크. 자가면역 질환의 치료를 위한 사이토카인 접합체
SG11202102930YA (en) 2018-11-08 2021-04-29 Synthorx Inc Interleukin 10 conjugates and uses thereof
EP3923974A4 (en) 2019-02-06 2023-02-08 Synthorx, Inc. IL-2 CONJUGATES AND METHODS OF USE THEREOF
EP4017540A1 (en) 2019-08-23 2022-06-29 Synthorx, Inc. Il-15 conjugates and uses thereof
US12234271B2 (en) 2019-09-10 2025-02-25 Synthorx, Inc. Il-2 conjugates and methods of use to treat autoimmune diseases
CA3153644A1 (en) * 2019-09-30 2021-04-08 Beijing Xuanyi Pharmasciences Co., Ltd. Protein-macromolecule conjugates and methods of use thereof
WO2022115563A1 (en) * 2020-11-25 2022-06-02 Prolynx Llc Extended release hydrogel conjugates of c-natriuretic peptides
JP2024512761A (ja) * 2021-03-29 2024-03-19 オーディー セラピューティクス リミテッド タンパク質－高分子コンジュゲートおよびその使用方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2295450B1 (en) * 2000-09-29 2015-01-28 Merck Sharp & Dohme Corp. Pegylated interleukin-10
US7910540B2 (en) * 2004-06-10 2011-03-22 Zymogenetics, Inc. Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation
ES2584381T3 (es) * 2010-05-05 2016-09-27 Prolynx Llc Liberación controlada de compuestos activos desde conjugados macromoleculares
US8703907B2 (en) * 2010-05-05 2014-04-22 Prolynx Llc Controlled drug release from dendrimers
EP2566334B1 (en) * 2010-05-05 2018-04-18 Prolynx, LLC Controlled drug release from solid supports
CA2848142C (en) * 2011-09-07 2021-05-18 Prolynx Llc Hydrogels with biodegradable crosslinking
US11401312B2 (en) * 2013-04-19 2022-08-02 Cytune Pharma Cytokine derived treatment with reduced vascular leak syndrome
MA39711A (fr) * 2014-04-03 2015-10-08 Nektar Therapeutics Conjugués d'une fraction d'il-15 et d'un polymère
AU2015301936B2 (en) * 2014-08-11 2019-03-07 Delinia, Inc. Modified IL-2 variants that selectively activate regulatory T cells for the treatment of autoimmune diseases
MX2018007304A (es) * 2015-12-21 2019-03-14 Armo Biosciences Inc Composiciones de interleucina-15 y sus usos.
KR20240141853A (ko) * 2017-08-03 2024-09-27 신톡스, 인크. 자가면역 질환의 치료를 위한 사이토카인 접합체

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