JP2025031829A5 - - Google Patents
Info
- Publication number
- JP2025031829A5 JP2025031829A5 JP2024224620A JP2024224620A JP2025031829A5 JP 2025031829 A5 JP2025031829 A5 JP 2025031829A5 JP 2024224620 A JP2024224620 A JP 2024224620A JP 2024224620 A JP2024224620 A JP 2024224620A JP 2025031829 A5 JP2025031829 A5 JP 2025031829A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody against
- aqueous solution
- human igg1
- protein
- igg1 isotype
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562208523P | 2015-08-21 | 2015-08-21 | |
| US62/208,523 | 2015-08-21 | ||
| JP2018509846A JP6968055B2 (ja) | 2015-08-21 | 2016-08-18 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
| JP2021124951A JP7258964B2 (ja) | 2015-08-21 | 2021-07-30 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
| JP2023061111A JP7610638B2 (ja) | 2015-08-21 | 2023-04-05 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023061111A Division JP7610638B2 (ja) | 2015-08-21 | 2023-04-05 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025031829A JP2025031829A (ja) | 2025-03-07 |
| JP2025031829A5 true JP2025031829A5 (https=) | 2025-10-14 |
Family
ID=56802471
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018509846A Active JP6968055B2 (ja) | 2015-08-21 | 2016-08-18 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
| JP2021124951A Active JP7258964B2 (ja) | 2015-08-21 | 2021-07-30 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
| JP2023061111A Active JP7610638B2 (ja) | 2015-08-21 | 2023-04-05 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
| JP2024224620A Pending JP2025031829A (ja) | 2015-08-21 | 2024-12-20 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018509846A Active JP6968055B2 (ja) | 2015-08-21 | 2016-08-18 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
| JP2021124951A Active JP7258964B2 (ja) | 2015-08-21 | 2021-07-30 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
| JP2023061111A Active JP7610638B2 (ja) | 2015-08-21 | 2023-04-05 | アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20180186832A1 (https=) |
| EP (1) | EP3337812B1 (https=) |
| JP (4) | JP6968055B2 (https=) |
| KR (2) | KR102691585B1 (https=) |
| CN (2) | CN107849087B (https=) |
| AU (1) | AU2016312909B2 (https=) |
| CA (1) | CA2992420A1 (https=) |
| ES (1) | ES2877532T3 (https=) |
| HR (1) | HRP20211026T1 (https=) |
| IL (1) | IL257146B2 (https=) |
| MX (1) | MX388197B (https=) |
| PL (1) | PL3337812T3 (https=) |
| SI (1) | SI3337812T1 (https=) |
| WO (1) | WO2017032686A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2017003116A (es) | 2014-09-10 | 2017-05-23 | Procter & Gamble | Trama de tela no tejida. |
| HRP20211737T1 (hr) | 2015-08-21 | 2022-02-18 | F. Hoffmann - La Roche Ag | Postupak za smanjenje proteina stanice domaćina u afinitetnoj kromatografiji |
| EP3337818B1 (en) * | 2015-08-21 | 2026-03-18 | F. Hoffmann-La Roche AG | Affinity chromatography purification with low conductivity wash buffer |
| SI3337812T1 (sl) | 2015-08-21 | 2021-08-31 | F. Hoffmann-La Roche Ag | Postopek za zmanjševanje beljakovin gostiteljske celice v afinitetni kromatografiji |
| EP3788150A4 (en) * | 2018-05-04 | 2022-01-26 | Sigma-Aldrich Co. LLC | PRODUCTION OF RECOMBINANT PROTEINS WITH REDUCED LEVELS OF HOST CELL PROTEINS |
| EP3826743A4 (en) * | 2018-07-25 | 2022-09-14 | Merck Sharp & Dohme Corp. | METHODS FOR SEPARATION OF HOST CELL LIPASES FROM A PRODUCTION PROTEIN IN CHROMATOGRAPHIC METHODS |
| WO2020153390A1 (ja) * | 2019-01-23 | 2020-07-30 | 第一三共株式会社 | 活性炭材料を使用する工程を含む抗体精製方法 |
| JP2023500775A (ja) * | 2019-09-23 | 2023-01-11 | メルク・シャープ・アンド・ドーム・エルエルシー | 宿主細胞タンパク質が減少し、ポリソルベート－８０安定性が増加した、抗ｃｔｌａ４モノクローナル抗体を含む方法および組成物 |
| WO2023284073A1 (zh) * | 2021-07-13 | 2023-01-19 | 江苏荃信生物医药股份有限公司 | 降低单克隆抗体生产中宿主细胞蛋白含量的亲和纯化方法、抗人ifnar1单克隆抗体浓缩溶液的制备方法以及液体制剂 |
| US20250223313A1 (en) * | 2022-01-14 | 2025-07-10 | Shattuck Labs, Inc. | Methods of contaminant removal from protein isolates |
| WO2024178239A1 (en) * | 2023-02-22 | 2024-08-29 | Shattuck Labs, Inc. | Engineered cell lines and uses thereof |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| GB9203459D0 (en) | 1992-02-19 | 1992-04-08 | Scotgen Ltd | Antibodies with germ-line variable regions |
| DE69738075T2 (de) | 1996-11-27 | 2008-05-21 | Genentech, Inc., South San Francisco | Affinitätsreinigung von polypeptiden an einer protein a-matrix |
| DE1257584T1 (de) | 2000-02-24 | 2003-05-28 | Lilly Co Eli | Humanisierte antikörper, die amyloid beta peptid demarkieren |
| WO2002072615A1 (en) | 2001-03-09 | 2002-09-19 | Chugai Seiyaku Kabushiki Kaisha | Method of purifying protein |
| TWI338009B (en) | 2001-10-29 | 2011-03-01 | Genentech Inc | Antibodies for inhibiting blood coagulation and methods of use thereof |
| AR038568A1 (es) | 2002-02-20 | 2005-01-19 | Hoffmann La Roche | Anticuerpos anti-a beta y su uso |
| EP3225625A1 (en) | 2002-09-11 | 2017-10-04 | Chugai Seiyaku Kabushiki Kaisha | Protein purification method |
| ATE468886T1 (de) | 2003-02-10 | 2010-06-15 | Applied Molecular Evolution | Abeta-bindende moleküle |
| PT1737891E (pt) | 2004-04-13 | 2013-04-16 | Hoffmann La Roche | Anticorpos anti p-selectina |
| CA2581208A1 (en) | 2004-08-30 | 2006-03-09 | Lonza Biologics Plc. | Affinity- plus ion exchange- chromatography for purifying antibodies |
| TWI306862B (en) | 2005-01-03 | 2009-03-01 | Hoffmann La Roche | Antibodies against il-13 receptor alpha 1 and uses thereof |
| PT1876236E (pt) | 2005-04-08 | 2014-10-22 | Chugai Pharmaceutical Co Ltd | Anticorpos para substituição da função do factor de coagulação sanguínea viii |
| ZA200710330B (en) | 2005-06-17 | 2009-12-30 | Wyeth Corp | Methods of purifying FC region containing proteins |
| MY155286A (en) * | 2005-12-12 | 2015-09-30 | Hoffmann La Roche | Antibodies against amyloid beta 4 with glycosylated in the variable region |
| WO2007109163A2 (en) | 2006-03-16 | 2007-09-27 | Amgen Inc | Wash buffer and method of using |
| EP2046833B9 (en) | 2006-07-14 | 2014-02-19 | AC Immune S.A. | Humanized antibody against amyloid beta |
| RU2474585C2 (ru) | 2007-01-22 | 2013-02-10 | Дженентек, Инк. | Осаждение и очистка белков полиэлектролитами |
| EP2278999B1 (en) * | 2008-04-21 | 2025-01-29 | Dompé farmaceutici S.p.A. | Auris formulations for treating otic diseases and conditions |
| RU2474588C2 (ru) | 2008-05-05 | 2013-02-10 | Новиммун Са | Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения |
| EP2116556B1 (en) | 2008-05-09 | 2016-03-23 | AbbVie Deutschland GmbH & Co KG | Antibodies to receptor of advanced glycation end products (RAGE) and uses thereof |
| BRPI0919879A2 (pt) | 2008-10-29 | 2016-02-16 | Wyeth Llc | métodos para purificação de moléculas de ligação a antígeno de domínio único |
| WO2011038894A1 (en) * | 2009-10-01 | 2011-04-07 | F. Hoffmann-La Roche Ag | Protein a chromatography |
| ES2982297T3 (es) | 2009-12-18 | 2024-10-15 | Novartis Ag | Método de cromatografía de afinidad |
| AR080794A1 (es) | 2010-03-26 | 2012-05-09 | Hoffmann La Roche | Anticuerpos bivalentes biespecificos anti- vegf/ anti-ang-2 |
| KR101860963B1 (ko) | 2010-04-23 | 2018-05-24 | 제넨테크, 인크. | 이종다량체 단백질의 생산 |
| EP2583973B1 (en) | 2010-06-21 | 2018-03-21 | Kyowa Hakko Kirin Co., Ltd. | Method for purifying protein using amino acid |
| WO2012047732A2 (en) | 2010-09-29 | 2012-04-12 | Genentech, Inc. | Antibody compositions and methods of use |
| TWI452136B (zh) | 2010-11-17 | 2014-09-11 | 中外製藥股份有限公司 | A multiple specific antigen-binding molecule that replaces the function of Factor VIII in blood coagulation |
| EP2714714B1 (en) | 2011-06-01 | 2018-06-20 | Novartis AG | Wash solution and method for affinity chromatography |
| WO2013033517A1 (en) | 2011-09-01 | 2013-03-07 | Human Genome Sciences, Inc. | Viral clearance methods |
| HUE035685T2 (en) | 2011-11-02 | 2018-05-28 | Hoffmann La Roche | Overload and elute chromatography |
| EP2849723B1 (en) * | 2012-05-18 | 2018-05-02 | Genentech, Inc. | High-concentration monoclonal antibody formulations |
| TW201348247A (zh) | 2012-05-21 | 2013-12-01 | Abbvie Inc | 利用蛋白質ａ親和性層析之非人類抗體之新穎純化 |
| UA118028C2 (uk) | 2013-04-03 | 2018-11-12 | Рош Глікарт Аг | Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування |
| EP2997036B1 (en) | 2013-05-15 | 2021-03-03 | Medimmune Limited | Purification of recombinantly produced polypeptides |
| TWI596107B (zh) * | 2013-06-25 | 2017-08-21 | 卡地拉保健有限公司 | 單株抗體之新穎純化方法 |
| US10144774B2 (en) * | 2013-07-01 | 2018-12-04 | Csl Behring Ag | Method for purifying IgG |
| CN105473612A (zh) * | 2013-08-19 | 2016-04-06 | 豪夫迈·罗氏有限公司 | 用羟基磷灰石层析分离双特异性抗体和双特异性抗体生产副产物 |
| CN120904322A (zh) * | 2013-09-13 | 2025-11-07 | 豪夫迈·罗氏有限公司 | 包含纯化的重组多肽的方法和组合物 |
| JPWO2015041218A1 (ja) | 2013-09-17 | 2017-03-02 | 株式会社カネカ | 新規抗体精製方法及びそれから得られる抗体（ＮｏｖｅｌＡｎｔｉｂｏｄｙＰｕｒｉｆｉｃａｔｉｏｎＭｅｔｈｏｄａｎｄＡｎｔｉｂｏｄｙｏｂｔａｉｎｅｄｔｈｅｒｅｆｒｏｍ）、並びに陽イオン交換基を用いた新規抗体精製法及びそれから得られる抗体（ＮｏｖｅｌＡｎｔｉｂｏｄｙＰｕｒｉｆｉｃａｔｉｏｎｍｅｔｈｏｄｕｓｉｎｇＣａｔｉｏｎＥｘｃｈａｎｇｅｒａｎｄＡｎｔｉｂｏｄｙｏｂｔａｉｎｅｄｔｈｅｒｅｆｒｏｍ） |
| JP2015083558A (ja) | 2013-09-18 | 2015-04-30 | 東ソー株式会社 | 抗体吸着剤ならびにそれを用いた抗体の精製方法および識別方法 |
| CN103497248B (zh) * | 2013-09-22 | 2016-08-10 | 中国抗体制药有限公司 | 一种从细胞培养上清中分离纯化抗体的方法 |
| US20160286398A1 (en) | 2015-03-23 | 2016-09-29 | Qualcomm Incorporated | Schedule selection and connection setup between devices participating in a nan data link |
| HRP20211737T1 (hr) | 2015-08-21 | 2022-02-18 | F. Hoffmann - La Roche Ag | Postupak za smanjenje proteina stanice domaćina u afinitetnoj kromatografiji |
| EP3337818B1 (en) | 2015-08-21 | 2026-03-18 | F. Hoffmann-La Roche AG | Affinity chromatography purification with low conductivity wash buffer |
| SI3337812T1 (sl) | 2015-08-21 | 2021-08-31 | F. Hoffmann-La Roche Ag | Postopek za zmanjševanje beljakovin gostiteljske celice v afinitetni kromatografiji |
| JP2021124951A (ja) | 2020-02-05 | 2021-08-30 | 富士通株式会社 | 情報処理システム、情報処理装置およびアクセス制御方法 |
-
2016
- 2016-08-18 SI SI201631245T patent/SI3337812T1/sl unknown
- 2016-08-18 JP JP2018509846A patent/JP6968055B2/ja active Active
- 2016-08-18 CN CN201680042079.1A patent/CN107849087B/zh active Active
- 2016-08-18 PL PL16757608T patent/PL3337812T3/pl unknown
- 2016-08-18 CN CN202211094785.4A patent/CN116063375A/zh active Pending
- 2016-08-18 AU AU2016312909A patent/AU2016312909B2/en active Active
- 2016-08-18 HR HRP20211026TT patent/HRP20211026T1/hr unknown
- 2016-08-18 IL IL257146A patent/IL257146B2/en unknown
- 2016-08-18 MX MX2018001536A patent/MX388197B/es unknown
- 2016-08-18 ES ES16757608T patent/ES2877532T3/es active Active
- 2016-08-18 WO PCT/EP2016/069604 patent/WO2017032686A1/en not_active Ceased
- 2016-08-18 KR KR1020187004868A patent/KR102691585B1/ko active Active
- 2016-08-18 CA CA2992420A patent/CA2992420A1/en active Pending
- 2016-08-18 KR KR1020247025729A patent/KR20240121902A/ko active Pending
- 2016-08-18 EP EP16757608.1A patent/EP3337812B1/en active Active
-
2018
- 2018-02-20 US US15/900,461 patent/US20180186832A1/en not_active Abandoned
-
2021
- 2021-05-24 US US17/328,408 patent/US12503487B2/en active Active
- 2021-07-30 JP JP2021124951A patent/JP7258964B2/ja active Active
-
2023
- 2023-04-05 JP JP2023061111A patent/JP7610638B2/ja active Active
-
2024
- 2024-12-20 JP JP2024224620A patent/JP2025031829A/ja active Pending
-
2025
- 2025-12-02 US US19/406,716 patent/US20260085090A1/en active Pending
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