JP2024534496A5 - - Google Patents

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Publication number
JP2024534496A5
JP2024534496A5 JP2024517415A JP2024517415A JP2024534496A5 JP 2024534496 A5 JP2024534496 A5 JP 2024534496A5 JP 2024517415 A JP2024517415 A JP 2024517415A JP 2024517415 A JP2024517415 A JP 2024517415A JP 2024534496 A5 JP2024534496 A5 JP 2024534496A5
Authority
JP
Japan
Prior art keywords
seq
combinations
mrna
fusion protein
grna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024517415A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024534496A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/076723 external-priority patent/WO2023049707A1/en
Publication of JP2024534496A publication Critical patent/JP2024534496A/ja
Publication of JP2024534496A5 publication Critical patent/JP2024534496A5/ja
Pending legal-status Critical Current

Links

JP2024517415A 2021-09-21 2022-09-20 ハプロ不全障害の処置のためのmRNAレギュロン療法 Pending JP2024534496A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163246689P 2021-09-21 2021-09-21
US63/246,689 2021-09-21
US202263352530P 2022-06-15 2022-06-15
US63/352,530 2022-06-15
PCT/US2022/076723 WO2023049707A1 (en) 2021-09-21 2022-09-20 Mrna regulon therapy for the treatment of haploinsufficiency disorders

Publications (2)

Publication Number Publication Date
JP2024534496A JP2024534496A (ja) 2024-09-20
JP2024534496A5 true JP2024534496A5 (enExample) 2025-09-10

Family

ID=85719677

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024517415A Pending JP2024534496A (ja) 2021-09-21 2022-09-20 ハプロ不全障害の処置のためのmRNAレギュロン療法

Country Status (8)

Country Link
US (1) US20250135035A1 (enExample)
EP (1) EP4404953A4 (enExample)
JP (1) JP2024534496A (enExample)
KR (1) KR20240099184A9 (enExample)
AU (1) AU2022349620A1 (enExample)
CA (1) CA3232214A1 (enExample)
MX (1) MX2024003412A (enExample)
WO (1) WO2023049707A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4514955A1 (en) * 2022-04-29 2025-03-05 The Johns Hopkins University Systems for enhancing mrna expression and uses thereof
WO2025165891A1 (en) 2024-01-29 2025-08-07 Arnatar Therapeutics, Inc Translation enhancing nucleic acid compounds: aso coupled translation - upregulation 1 (act-up1) and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015221026A (ja) * 2014-05-23 2015-12-10 公立大学法人名古屋市立大学 人工合成mRNAの翻訳効率化方法
US20180312873A1 (en) * 2015-10-20 2018-11-01 10X Genomics, Inc. Method and systems for high throughput single cell genetic manipulation
EP3579858A4 (en) * 2017-02-07 2020-12-23 The Regents of The University of California GENE THERAPY AGAINST HAPLOINSUFFICIENCY
KR20260009385A (ko) * 2017-08-25 2026-01-19 스톡 테라퓨틱스, 인크. 병태 및 질환 치료용 안티센스 올리고머
EP4013873A1 (en) * 2019-08-16 2022-06-22 Massachusetts Institute Of Technology Targeted trans-splicing using crispr/cas13
US20230078498A1 (en) * 2020-02-07 2023-03-16 University Of Rochester Targeted Translation of RNA with CRISPR-Cas13 to Enhance Protein Synthesis

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