JP2022502044A5 - - Google Patents
Info
- Publication number
- JP2022502044A5 JP2022502044A5 JP2021517022A JP2021517022A JP2022502044A5 JP 2022502044 A5 JP2022502044 A5 JP 2022502044A5 JP 2021517022 A JP2021517022 A JP 2021517022A JP 2021517022 A JP2021517022 A JP 2021517022A JP 2022502044 A5 JP2022502044 A5 JP 2022502044A5
- Authority
- JP
- Japan
- Prior art keywords
- syndrome
- expression vector
- vector according
- seq
- type
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024170988A JP2025010148A (ja) | 2018-09-26 | 2024-09-30 | タンパク質発現の増加および／またはハプロ不全障害の治療のための方法および組成物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862736847P | 2018-09-26 | 2018-09-26 | |
| US62/736,847 | 2018-09-26 | ||
| PCT/US2019/053268 WO2020069199A1 (en) | 2018-09-26 | 2019-09-26 | Methods and compositions for increasing protein expression and/or treating a haploinsufficiency disorder |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024170988A Division JP2025010148A (ja) | 2018-09-26 | 2024-09-30 | タンパク質発現の増加および／またはハプロ不全障害の治療のための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022502044A JP2022502044A (ja) | 2022-01-11 |
| JP2022502044A5 true JP2022502044A5 (enExample) | 2022-10-04 |
Family
ID=69949913
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021517022A Pending JP2022502044A (ja) | 2018-09-26 | 2019-09-26 | タンパク質発現の増加および／またはハプロ不全障害の治療のための方法および組成物 |
| JP2024170988A Pending JP2025010148A (ja) | 2018-09-26 | 2024-09-30 | タンパク質発現の増加および／またはハプロ不全障害の治療のための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024170988A Pending JP2025010148A (ja) | 2018-09-26 | 2024-09-30 | タンパク質発現の増加および／またはハプロ不全障害の治療のための方法および組成物 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US12281314B2 (enExample) |
| EP (1) | EP3856905A4 (enExample) |
| JP (2) | JP2022502044A (enExample) |
| KR (1) | KR102814622B1 (enExample) |
| CN (1) | CN113195719A (enExample) |
| AU (1) | AU2019350871B2 (enExample) |
| BR (1) | BR112021005788A2 (enExample) |
| CA (1) | CA3114109A1 (enExample) |
| CL (1) | CL2021000747A1 (enExample) |
| CO (1) | CO2021005040A2 (enExample) |
| EA (1) | EA202190736A1 (enExample) |
| IL (1) | IL281848A (enExample) |
| MX (1) | MX2021003567A (enExample) |
| WO (1) | WO2020069199A1 (enExample) |
| ZA (1) | ZA202102302B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7712270B2 (ja) | 2019-11-01 | 2025-07-23 | テバード バイオサイエンシズ インコーポレイテッド | 未成熟終止コドン媒介障害を処置するための方法および組成物 |
| CA3160097A1 (en) * | 2019-11-04 | 2021-05-14 | Flagship Pioneering, Inc. | Trem compositions for con-rare codons and related uses |
| US20230203510A1 (en) * | 2020-05-29 | 2023-06-29 | Flagship Pioneering Innovations Vi, Llc | Trem compositions and methods relating thereto |
| EP4158032A2 (en) * | 2020-05-29 | 2023-04-05 | Flagship Pioneering Innovations VI, LLC | Trem compositions and methods relating thereto |
| EP4334450A4 (en) * | 2021-05-05 | 2025-06-18 | Tevard Biosciences, Inc. | Methods and compositions for treating a premature termination codon-mediated disorder |
| CA3249261A1 (en) | 2022-04-18 | 2023-10-26 | Vertex Pharmaceuticals Incorporated | COMPOSITIONS AND PROCESSES TO IMPROVE ADENE-ASSOCIATED VIRUS (AAV) THERAPY AND REDUCE AAV TROPISM TO THE LIVER |
| CN117257958B (zh) * | 2023-11-21 | 2024-02-09 | 四川大学华西医院 | Trps1抑制剂的新用途及用于治疗和/或预防雄激素性秃发的药物 |
| WO2025176166A1 (en) * | 2024-02-21 | 2025-08-28 | Zhuhai Codone Biotechnology Co., Ltd. | Engineered trna expression cassette |
| WO2026001270A1 (en) * | 2024-06-24 | 2026-01-02 | Zhuhai Codone Biotechnology Co., Ltd. | Engineered trna molecules and methods |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1114149A1 (en) | 1998-09-17 | 2001-07-11 | SmithKline Beecham Corporation | Rnase p polypeptides |
| US20040142325A1 (en) | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
| JP4406731B2 (ja) * | 2005-03-31 | 2010-02-03 | 国立大学法人 岡山大学 | 部位特異的アミノ酸導入法のための新規な直交化ｔＲＮＡ |
| WO2008127900A1 (en) * | 2007-04-13 | 2008-10-23 | The Salk Institute For Biological Studies | Methods of genetically encoding unnatural amino acids in eukaryotic cells using orthogonal trna/synthetase pairs |
| US20120283116A1 (en) * | 2009-09-11 | 2012-11-08 | Leppert Mark F | Mutant Sodium Channel Nav1.7 and Methods Related Thereto |
| US9676810B2 (en) * | 2010-07-08 | 2017-06-13 | The Brigham And Women's Hospital, Inc. | Neuroprotective molecules and methods of treating neurological disorders and inducing stress granules |
| US20130129668A1 (en) * | 2011-09-01 | 2013-05-23 | The Regents Of The University Of California | Diagnosis and treatment of arthritis using epigenetics |
| WO2014052855A1 (en) | 2012-09-27 | 2014-04-03 | Population Diagnostics, Inc. | Methods and compositions for screening and treating developmental disorders |
| EP3052624A1 (en) | 2013-10-02 | 2016-08-10 | Wageningen Universiteit | Systematic optimization of coding sequence for functional protein expression |
| EP3362087A1 (en) | 2015-10-15 | 2018-08-22 | The Scripps Research Institute | BINDING ACTIVITY OF AMINOACYL-tRNA SYNTHETASE IN CHARCOT-MARIE-TOOTH (CMT) NEUROPATHY AND CMT-RELATED NEUROLOGICAL DISEASES |
| CN116059236A (zh) * | 2015-12-14 | 2023-05-05 | 冷泉港实验室 | 用于治疗常染色体显性精神发育迟滞5型和Dravet综合征的反义寡聚体 |
| WO2017193051A1 (en) | 2016-05-06 | 2017-11-09 | The Trustees Of Princeton University | Methods of monitoring rnase l activity |
| PL3458074T3 (pl) * | 2016-05-16 | 2024-11-12 | Board Of Regents Of The University Of Texas System | KOMPOZYCJA DO DOSTARCZANIA tRNA W POSTACI NANOCZĄSTEK I SPOSOBY ICH STOSOWANIA |
| WO2018104385A1 (en) | 2016-12-07 | 2018-06-14 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Codon optimization |
| JP2022534988A (ja) | 2019-05-31 | 2022-08-04 | フラッグシップ パイオニアリング， インコーポレイテッド | ｔＲＮＡプールを調節するためのＴＲＥＭの使用 |
-
2019
- 2019-09-26 EA EA202190736A patent/EA202190736A1/ru unknown
- 2019-09-26 JP JP2021517022A patent/JP2022502044A/ja active Pending
- 2019-09-26 EP EP19866182.9A patent/EP3856905A4/en active Pending
- 2019-09-26 WO PCT/US2019/053268 patent/WO2020069199A1/en not_active Ceased
- 2019-09-26 US US17/280,369 patent/US12281314B2/en active Active
- 2019-09-26 MX MX2021003567A patent/MX2021003567A/es unknown
- 2019-09-26 BR BR112021005788-9A patent/BR112021005788A2/pt not_active Application Discontinuation
- 2019-09-26 KR KR1020217012452A patent/KR102814622B1/ko active Active
- 2019-09-26 CN CN201980077435.7A patent/CN113195719A/zh active Pending
- 2019-09-26 CA CA3114109A patent/CA3114109A1/en active Pending
- 2019-09-26 AU AU2019350871A patent/AU2019350871B2/en active Active
-
2021
- 2021-03-25 IL IL281848A patent/IL281848A/en unknown
- 2021-03-25 CL CL2021000747A patent/CL2021000747A1/es unknown
- 2021-04-07 ZA ZA2021/02302A patent/ZA202102302B/en unknown
- 2021-04-20 CO CONC2021/0005040A patent/CO2021005040A2/es unknown
-
2024
- 2024-09-30 JP JP2024170988A patent/JP2025010148A/ja active Pending
-
2025
- 2025-04-22 US US19/185,430 patent/US20260009041A1/en active Pending
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