JP2024526882A - Ｋｉｆ１８ａ阻害剤化合物の塩及び固体状形態 - Google Patents

Ｋｉｆ１８ａ阻害剤化合物の塩及び固体状形態 Download PDF

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JP2024526882A
JP2024526882A JP2024503546A JP2024503546A JP2024526882A JP 2024526882 A JP2024526882 A JP 2024526882A JP 2024503546 A JP2024503546 A JP 2024503546A JP 2024503546 A JP2024503546 A JP 2024503546A JP 2024526882 A JP2024526882 A JP 2024526882A
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compound
solvate
cancer
crystalline
crystalline compound
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ウー，チャン
アガーワル，プラシャント
アール． ロゼリ，アンドレアス
パク，ヒュンスー
ジェイ． フローン，マイケル
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アムジエン・インコーポレーテツド
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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JP2024503546A 2021-07-21 2022-07-21 Ｋｉｆ１８ａ阻害剤化合物の塩及び固体状形態 Pending JP2024526882A (ja)

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US202163224208P 2021-07-21 2021-07-21
US63/224,208 2021-07-21
PCT/US2022/037928 WO2023004075A1 (en) 2021-07-21 2022-07-21 Salts and solid state forms of a kif18a inhibitor compound

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JP2024526882A true JP2024526882A (ja) 2024-07-19
JP2024526882A5 JP2024526882A5 (https=) 2025-07-29

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JP2024503546A Pending JP2024526882A (ja) 2021-07-21 2022-07-21 Ｋｉｆ１８ａ阻害剤化合物の塩及び固体状形態

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US (1) US20240327384A1 (https=)
EP (1) EP4373818A1 (https=)
JP (1) JP2024526882A (https=)
KR (1) KR20240051338A (https=)
CN (1) CN117940416A (https=)
AR (1) AR126537A1 (https=)
AU (1) AU2022313961A1 (https=)
CA (1) CA3226614A1 (https=)
IL (1) IL310234A (https=)
MX (1) MX2024000990A (https=)
TW (1) TW202321213A (https=)
UY (1) UY39866A (https=)
WO (1) WO2023004075A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA54543A (fr) 2018-12-20 2022-03-30 Amgen Inc Inhibiteurs de kif18a
IL310863A (en) 2021-08-26 2024-04-01 Volastra Therapeutics Inc Spiro indoline inhibitors of kif18a
EP4509505A4 (en) * 2022-04-15 2026-04-15 Wuhan Humanwell Innovative Drug Res And Development Center Limited Company KIF18A INHIBITOR AND ITS USAGE
TW202416973A (zh) 2022-08-18 2024-05-01 美商雅客森醫療公司 Ｋｉｆ１８ａ抑制劑及其用途
CN116535400B (zh) * 2023-04-26 2024-08-16 上海湃隆生物科技有限公司 氮杂螺环化合物及其应用
WO2025077882A1 (zh) * 2023-10-13 2025-04-17 武汉人福创新药物研发中心有限公司 Kif18a抑制剂化合物的盐、晶型及其制备方法和用途
WO2025185704A1 (zh) * 2024-03-07 2025-09-12 长春金赛药业有限责任公司 一种kif18a抑制剂的晶型及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8576985B2 (en) 2009-09-01 2013-11-05 Aptuit (West Lafayette) Llc Methods for indexing solid forms of compounds
MA54543A (fr) 2018-12-20 2022-03-30 Amgen Inc Inhibiteurs de kif18a
MX2022012992A (es) * 2020-04-14 2022-11-08 Amgen Inc Inhibidores de kif18a para el tratamiento de enfermedades neoplasicas.

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CA3226614A1 (en) 2023-01-26
US20240327384A1 (en) 2024-10-03
IL310234A (en) 2024-03-01
AR126537A1 (es) 2023-10-18
AU2022313961A1 (en) 2024-02-08
TW202321213A (zh) 2023-06-01
EP4373818A1 (en) 2024-05-29
KR20240051338A (ko) 2024-04-19
UY39866A (es) 2023-01-31
CN117940416A (zh) 2024-04-26
MX2024000990A (es) 2024-02-12

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