JP2024524922A5 - - Google Patents

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Publication number
JP2024524922A5
JP2024524922A5 JP2023577531A JP2023577531A JP2024524922A5 JP 2024524922 A5 JP2024524922 A5 JP 2024524922A5 JP 2023577531 A JP2023577531 A JP 2023577531A JP 2023577531 A JP2023577531 A JP 2023577531A JP 2024524922 A5 JP2024524922 A5 JP 2024524922A5
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JP
Japan
Prior art keywords
domain
seq
protease
amino acid
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023577531A
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English (en)
Japanese (ja)
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JP2024524922A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/033893 external-priority patent/WO2022266396A1/en
Publication of JP2024524922A publication Critical patent/JP2024524922A/ja
Publication of JP2024524922A5 publication Critical patent/JP2024524922A5/ja
Pending legal-status Critical Current

Links

JP2023577531A 2021-06-16 2022-06-16 武装化キメラ受容体及びその使用方法 Pending JP2024524922A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163211468P 2021-06-16 2021-06-16
US63/211,468 2021-06-16
US202263305155P 2022-01-31 2022-01-31
US63/305,155 2022-01-31
PCT/US2022/033893 WO2022266396A1 (en) 2021-06-16 2022-06-16 Armed chimeric receptors and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2024524922A JP2024524922A (ja) 2024-07-09
JP2024524922A5 true JP2024524922A5 (enExample) 2024-08-06

Family

ID=84526773

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577531A Pending JP2024524922A (ja) 2021-06-16 2022-06-16 武装化キメラ受容体及びその使用方法

Country Status (9)

Country Link
US (1) US20240277766A1 (enExample)
EP (1) EP4355341A4 (enExample)
JP (1) JP2024524922A (enExample)
KR (1) KR20240022575A (enExample)
AU (1) AU2022294896A1 (enExample)
CA (1) CA3221897A1 (enExample)
IL (1) IL309161A (enExample)
TW (1) TW202317753A (enExample)
WO (1) WO2022266396A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020092839A1 (en) 2018-10-31 2020-05-07 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
EP3873540A4 (en) 2018-10-31 2022-07-27 Mayo Foundation for Medical Education and Research METHODS AND MATERIALS FOR THE TREATMENT OF CANCER
WO2024102943A1 (en) * 2022-11-09 2024-05-16 Senti Biosciences, Inc. Armed chimeric receptors and methods of use thereof
CN120112547A (zh) * 2022-11-16 2025-06-06 瑞泽恩制药公司 包含膜结合il-12和蛋白酶可裂解接头的嵌合蛋白
WO2025106924A1 (en) * 2023-11-16 2025-05-22 Senti Biosciences, Inc. Methods of enhancing engineered immune cell cytotoxicity
WO2025179221A1 (en) * 2024-02-22 2025-08-28 Senti Biosciences, Inc. Compositions and methods for armored cell based therapies
WO2026077446A1 (en) * 2024-10-12 2026-04-16 Nanjing Legend Biotech Co., Ltd. Engineered il-15 constructs and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130010121A (ko) * 2010-03-23 2013-01-25 인트렉손 코포레이션 치료적 단백질을 조건부로 발현하는 벡터，상기 벡터를 포함하는 숙주 세포 및 이의 용도
EP3568474A1 (en) * 2017-01-10 2019-11-20 Intrexon Corporation Modulating expression of polypeptides via new gene switch expression systems
WO2019014390A1 (en) * 2017-07-12 2019-01-17 Refuge Biotechnologies, Inc. METHODS AND SYSTEMS FOR CONDITIONAL REGULATION OF GENE EXPRESSION
EP3784256A4 (en) * 2018-04-27 2022-06-29 Baylor College of Medicine Car t cells with one or more interleukins
CA3102641A1 (en) * 2018-06-22 2019-12-26 Kite Pharma, Inc. Chimeric transmembrane proteins and uses thereof
AU2019359890B2 (en) * 2018-10-17 2024-10-24 Senti Biosciences, Inc. Combinatorial cancer immunotherapy
EP3907280A4 (en) * 2018-12-13 2022-06-22 CRAGE medical Co., Limited ANTI-GPC3 IMMUNE EFFECTOR CELL AND USE THEREOF
JP7663513B2 (ja) * 2019-05-16 2025-04-16 トラスティーズ オブ ボストン ユニバーシティ 調節された合成遺伝子発現システム
WO2021087205A1 (en) * 2019-11-01 2021-05-06 Senti Biosciences, Inc. Chimeric receptor sensors
JP7792335B2 (ja) * 2019-12-12 2025-12-25 センティ バイオサイエンシズ インコーポレイテッド 細胞の調節されたアーマリングのための方法及び組成物
KR20230117107A (ko) * 2020-11-04 2023-08-07 센티 바이오사이언시스, 인코포레이티드 단백질 페이로드 방출

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