JP2024524922A5 - - Google Patents

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Publication number
JP2024524922A5
JP2024524922A5 JP2023577531A JP2023577531A JP2024524922A5 JP 2024524922 A5 JP2024524922 A5 JP 2024524922A5 JP 2023577531 A JP2023577531 A JP 2023577531A JP 2023577531 A JP2023577531 A JP 2023577531A JP 2024524922 A5 JP2024524922 A5 JP 2024524922A5
Authority
JP
Japan
Prior art keywords
domain
seq
protease
amino acid
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023577531A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024524922A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/033893 external-priority patent/WO2022266396A1/en
Publication of JP2024524922A publication Critical patent/JP2024524922A/ja
Publication of JP2024524922A5 publication Critical patent/JP2024524922A5/ja
Pending legal-status Critical Current

Links

JP2023577531A 2021-06-16 2022-06-16 武装化キメラ受容体及びその使用方法 Pending JP2024524922A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163211468P 2021-06-16 2021-06-16
US63/211,468 2021-06-16
US202263305155P 2022-01-31 2022-01-31
US63/305,155 2022-01-31
PCT/US2022/033893 WO2022266396A1 (en) 2021-06-16 2022-06-16 Armed chimeric receptors and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2024524922A JP2024524922A (ja) 2024-07-09
JP2024524922A5 true JP2024524922A5 (enExample) 2024-08-06

Family

ID=84526773

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023577531A Pending JP2024524922A (ja) 2021-06-16 2022-06-16 武装化キメラ受容体及びその使用方法

Country Status (9)

Country Link
US (1) US20240277766A1 (enExample)
EP (1) EP4355341A4 (enExample)
JP (1) JP2024524922A (enExample)
KR (1) KR20240022575A (enExample)
AU (1) AU2022294896A1 (enExample)
CA (1) CA3221897A1 (enExample)
IL (1) IL309161A (enExample)
TW (1) TW202317753A (enExample)
WO (1) WO2022266396A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12624086B2 (en) 2018-10-31 2026-05-12 Mayo Foundation For Medical Education And Research Materials and methods for treating cancer
US12264189B2 (en) 2018-10-31 2025-04-01 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
US12257286B2 (en) 2018-10-31 2025-03-25 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
WO2024102943A1 (en) * 2022-11-09 2024-05-16 Senti Biosciences, Inc. Armed chimeric receptors and methods of use thereof
JP2025538387A (ja) * 2022-11-16 2025-11-28 リジェネロン・ファーマシューティカルズ・インコーポレイテッド プロテアーゼ切断可能なリンカーを有する膜結合ｉｌ－１２を含むキメラタンパク質
KR20260114555A (ko) * 2023-11-16 2026-07-22 센티 바이오사이언시스, 인코포레이티드 조작된 면역 세포의 세포독성을 향상시키는 방법
WO2025179221A1 (en) * 2024-02-22 2025-08-28 Senti Biosciences, Inc. Compositions and methods for armored cell based therapies
WO2026077446A1 (en) * 2024-10-12 2026-04-16 Nanjing Legend Biotech Co., Ltd. Engineered il-15 constructs and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2550359B1 (en) * 2010-03-23 2017-08-09 Intrexon Corporation Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof
CA3049652A1 (en) * 2017-01-10 2018-07-19 Intrexon Corporation Modulating expression of polypeptides via new gene switch expression systems
AU2018301667A1 (en) * 2017-07-12 2020-02-06 Fundação D. Anna De Sommer Champalimaud E Dr. Carlos Montez Champalimaud Foundation Methods and systems for conditionally regulating gene expression
WO2019210293A1 (en) * 2018-04-27 2019-10-31 Baylor College Of Medicine Car t cells with one or more interleukins
CN112368298A (zh) * 2018-06-22 2021-02-12 凯德药业股份有限公司 嵌合跨膜蛋白及其用途
CA3116138A1 (en) * 2018-10-17 2020-04-23 Senti Biosciences, Inc. Combinatorial cancer immunotherapy
JP2022512450A (ja) * 2018-12-13 2022-02-03 カースゲン セラピューティクス カンパニー リミテッド Ｇｐｃ３を標的とする免疫エフェクター細胞およびその応用
AU2020275884B2 (en) * 2019-05-16 2026-05-14 Trustees Of Boston University Regulated synthetic gene expression systems
US20220396609A1 (en) * 2019-11-01 2022-12-15 Senti Biosciences, Inc. Chimeric receptor sensors
CA3160614A1 (en) * 2019-12-12 2021-06-17 Marcela GUZMAN AYALA Method and compositions for regulated armoring of cells
EP4240380A4 (en) * 2020-11-04 2024-10-16 Senti Biosciences, Inc. PROTEIN PAYLOAD RELEASE

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