JP2024524922A - 武装化キメラ受容体及びその使用方法 - Google Patents

武装化キメラ受容体及びその使用方法 Download PDF

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JP2024524922A
JP2024524922A JP2023577531A JP2023577531A JP2024524922A JP 2024524922 A JP2024524922 A JP 2024524922A JP 2023577531 A JP2023577531 A JP 2023577531A JP 2023577531 A JP2023577531 A JP 2023577531A JP 2024524922 A JP2024524922 A JP 2024524922A
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protease
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protein
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アヤラ マルセラ グズマン
ラッセル モリソン ゴードリー
ミシェル エリザベス ハング
ゲイリー リー
ティモシー クアン－タ ル
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センティ バイオサイエンシズ インコーポレイテッド
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JP2023577531A 2021-06-16 2022-06-16 武装化キメラ受容体及びその使用方法 Pending JP2024524922A (ja)

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US202163211468P 2021-06-16 2021-06-16
US63/211,468 2021-06-16
US202263305155P 2022-01-31 2022-01-31
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PCT/US2022/033893 WO2022266396A1 (en) 2021-06-16 2022-06-16 Armed chimeric receptors and methods of use thereof

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JP2025538387A (ja) * 2022-11-16 2025-11-28 リジェネロン・ファーマシューティカルズ・インコーポレイテッド プロテアーゼ切断可能なリンカーを有する膜結合ｉｌ－１２を含むキメラタンパク質
KR20260114555A (ko) * 2023-11-16 2026-07-22 센티 바이오사이언시스, 인코포레이티드 조작된 면역 세포의 세포독성을 향상시키는 방법
WO2025179221A1 (en) * 2024-02-22 2025-08-28 Senti Biosciences, Inc. Compositions and methods for armored cell based therapies
WO2026077446A1 (en) * 2024-10-12 2026-04-16 Nanjing Legend Biotech Co., Ltd. Engineered il-15 constructs and uses thereof

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CA3160614A1 (en) * 2019-12-12 2021-06-17 Marcela GUZMAN AYALA Method and compositions for regulated armoring of cells
EP4240380A4 (en) * 2020-11-04 2024-10-16 Senti Biosciences, Inc. PROTEIN PAYLOAD RELEASE

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