JP2024518447A5 - - Google Patents

Info

Publication number
JP2024518447A5
JP2024518447A5 JP2023568613A JP2023568613A JP2024518447A5 JP 2024518447 A5 JP2024518447 A5 JP 2024518447A5 JP 2023568613 A JP2023568613 A JP 2023568613A JP 2023568613 A JP2023568613 A JP 2023568613A JP 2024518447 A5 JP2024518447 A5 JP 2024518447A5
Authority
JP
Japan
Prior art keywords
hydrogen
alkyl
haloalkyl
halogen
stereoisomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023568613A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024518447A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2022/051167 external-priority patent/WO2022234299A1/en
Publication of JP2024518447A publication Critical patent/JP2024518447A/ja
Publication of JP2024518447A5 publication Critical patent/JP2024518447A5/ja
Pending legal-status Critical Current

Links

JP2023568613A 2021-05-06 2022-05-06 PKC-θモジュレーター Pending JP2024518447A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2106486.0 2021-05-06
GB202106486 2021-05-06
PCT/GB2022/051167 WO2022234299A1 (en) 2021-05-06 2022-05-06 Pkc-theta modulators

Publications (2)

Publication Number Publication Date
JP2024518447A JP2024518447A (ja) 2024-05-01
JP2024518447A5 true JP2024518447A5 (https=) 2025-11-18

Family

ID=82100804

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023568613A Pending JP2024518447A (ja) 2021-05-06 2022-05-06 PKC-θモジュレーター

Country Status (14)

Country Link
US (1) US20240239794A1 (https=)
EP (1) EP4334316A1 (https=)
JP (1) JP2024518447A (https=)
KR (1) KR20240024063A (https=)
CN (1) CN117295738A (https=)
AU (1) AU2022269348A1 (https=)
BR (1) BR112023022883A2 (https=)
CA (1) CA3214088A1 (https=)
CL (1) CL2023003247A1 (https=)
CO (1) CO2023015005A2 (https=)
IL (1) IL307669A (https=)
MX (1) MX2023013012A (https=)
PE (1) PE20250019A1 (https=)
WO (1) WO2022234299A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022234298A1 (en) * 2021-05-06 2022-11-10 Exscientia Ai Limited Pkc-theta modulators
CN118772140B (zh) * 2023-04-07 2026-04-17 四川大学 一类化合物及其在治疗hDHODH介导的疾病中的用途
WO2025255294A1 (en) * 2024-06-06 2025-12-11 Bristol-Myers Squibb Company Pkc-theta inhibitors, compositions, and methods of use
WO2025255298A1 (en) * 2024-06-06 2025-12-11 Bristol-Myers Squibb Company Pkc-theta inhibitors, compositions, and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200924762A (en) * 2007-11-02 2009-06-16 Vertex Pharma Kinase inhibitors
GB0920382D0 (en) 2009-11-20 2010-01-06 Univ Dundee Design of molecules
CN102471342A (zh) * 2010-05-05 2012-05-23 沃泰克斯药物股份有限公司 用作PKC-θ抑制剂的4取代的吡唑并吡啶类
US9556126B2 (en) 2013-12-20 2017-01-31 Signal Pharmaceuticals, Llc Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith
AU2020284742B2 (en) * 2019-05-28 2026-03-05 Mankind Pharma Ltd. Novel compounds for inhibition of Janus Kinase 1
WO2022234298A1 (en) * 2021-05-06 2022-11-10 Exscientia Ai Limited Pkc-theta modulators

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