JP2024517861A5 - - Google Patents

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Publication number
JP2024517861A5
JP2024517861A5 JP2023568277A JP2023568277A JP2024517861A5 JP 2024517861 A5 JP2024517861 A5 JP 2024517861A5 JP 2023568277 A JP2023568277 A JP 2023568277A JP 2023568277 A JP2023568277 A JP 2023568277A JP 2024517861 A5 JP2024517861 A5 JP 2024517861A5
Authority
JP
Japan
Prior art keywords
stereoisomers
stereoisomer
pharmaceutically acceptable
solvate
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023568277A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024517861A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2022/051166 external-priority patent/WO2022234298A1/en
Publication of JP2024517861A publication Critical patent/JP2024517861A/ja
Publication of JP2024517861A5 publication Critical patent/JP2024517861A5/ja
Pending legal-status Critical Current

Links

JP2023568277A 2021-05-06 2022-05-06 ＰＫＣ－θモジュレーター Pending JP2024517861A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB202106485 2021-05-06
GB2106485.2 2021-05-06
PCT/GB2022/051166 WO2022234298A1 (en) 2021-05-06 2022-05-06 Pkc-theta modulators

Publications (2)

Publication Number Publication Date
JP2024517861A JP2024517861A (ja) 2024-04-23
JP2024517861A5 true JP2024517861A5 (https=) 2025-12-01

Family

ID=82100190

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023568277A Pending JP2024517861A (ja) 2021-05-06 2022-05-06 ＰＫＣ－θモジュレーター

Country Status (14)

Country Link
US (2) US20240262821A1 (https=)
EP (1) EP4333982A1 (https=)
JP (1) JP2024517861A (https=)
KR (1) KR20240024062A (https=)
CN (1) CN117355522A (https=)
AU (1) AU2022269883A1 (https=)
BR (1) BR112023022706A2 (https=)
CA (1) CA3213703A1 (https=)
CL (1) CL2023003246A1 (https=)
CO (1) CO2023014939A2 (https=)
IL (1) IL307665A (https=)
MX (1) MX2023013013A (https=)
PE (1) PE20240070A1 (https=)
WO (1) WO2022234298A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20250019A1 (es) * 2021-05-06 2025-01-07 Exscientia Ai Ltd MODULADORES DE PKC-theta
WO2025235367A1 (en) * 2024-05-06 2025-11-13 D. E. Shaw Research, Llc Azaindolinone compounds as kca3.1 potassium channel blockers
WO2025255292A1 (en) * 2024-06-06 2025-12-11 Bristol-Myers Squibb Company Pkc-theta inhibitors, compositions, and methods of use
WO2025255288A1 (en) * 2024-06-06 2025-12-11 Bristol-Myers Squibb Company Pkc-theta inhibitors, compositions, and methods of use
WO2025255298A1 (en) * 2024-06-06 2025-12-11 Bristol-Myers Squibb Company Pkc-theta inhibitors, compositions, and methods of use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200924762A (en) * 2007-11-02 2009-06-16 Vertex Pharma Kinase inhibitors
EP2244711A4 (en) * 2008-02-04 2011-08-24 Cytokinetics Inc CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS
GB0920382D0 (en) 2009-11-20 2010-01-06 Univ Dundee Design of molecules
CN102471342A (zh) * 2010-05-05 2012-05-23 沃泰克斯药物股份有限公司 用作PKC-θ抑制剂的4取代的吡唑并吡啶类
US9556126B2 (en) 2013-12-20 2017-01-31 Signal Pharmaceuticals, Llc Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith
EP3087067B1 (en) * 2013-12-26 2018-10-24 Takeda Pharmaceutical Company Limited 4-(piperrazin-1-yl)-pyrrolidin-2-one compounds as monoacylglycerol lipase (magl) inhibitors
CN109641892B (zh) * 2016-08-16 2021-07-02 默克专利有限公司 用作可逆btk抑制剂的2-氧代-咪唑并吡啶及其用途
AU2020284742B2 (en) * 2019-05-28 2026-03-05 Mankind Pharma Ltd. Novel compounds for inhibition of Janus Kinase 1
CN112480116B (zh) * 2019-09-11 2024-03-29 南京正大天晴制药有限公司 Pkb抑制剂
PE20250019A1 (es) * 2021-05-06 2025-01-07 Exscientia Ai Ltd MODULADORES DE PKC-theta

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