JP2023509422A5 - - Google Patents
Info
- Publication number
- JP2023509422A5 JP2023509422A5 JP2022540328A JP2022540328A JP2023509422A5 JP 2023509422 A5 JP2023509422 A5 JP 2023509422A5 JP 2022540328 A JP2022540328 A JP 2022540328A JP 2022540328 A JP2022540328 A JP 2022540328A JP 2023509422 A5 JP2023509422 A5 JP 2023509422A5
- Authority
- JP
- Japan
- Prior art keywords
- independently selected
- alkyl
- group
- substituted
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962955839P | 2019-12-31 | 2019-12-31 | |
| US62/955,839 | 2019-12-31 | ||
| US202063090538P | 2020-10-12 | 2020-10-12 | |
| US63/090,538 | 2020-10-12 | ||
| PCT/US2020/067483 WO2021138434A1 (en) | 2019-12-31 | 2020-12-30 | Compounds and compositions for treating conditions associated with sting activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023509422A JP2023509422A (ja) | 2023-03-08 |
| JP2023509422A5 true JP2023509422A5 (https=) | 2024-01-11 |
| JP7756643B2 JP7756643B2 (ja) | 2025-10-20 |
Family
ID=74206237
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022540328A Active JP7756643B2 (ja) | 2019-12-31 | 2020-12-30 | Ｓｔｉｎｇ活性に関連する状態を治療するための化合物および組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230127839A1 (https=) |
| EP (1) | EP4085051A1 (https=) |
| JP (1) | JP7756643B2 (https=) |
| CN (2) | CN115348957B (https=) |
| PY (1) | PY2089159A (https=) |
| TW (1) | TW202136239A (https=) |
| UY (1) | UY39006A (https=) |
| WO (1) | WO2021138434A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120004785A (zh) | 2018-07-03 | 2025-05-16 | 诺华制药股份有限公司 | 用于治疗与sting活性有关的疾病的化合物和组合物 |
| EP4267128A1 (en) | 2020-12-22 | 2023-11-01 | IFM Due, Inc. | Methods of treating cancer |
| US20240060982A1 (en) | 2020-12-22 | 2024-02-22 | Ifm Due, Inc. | Methods of treating cancer |
| JP2024500874A (ja) | 2020-12-22 | 2024-01-10 | アイエフエム デュー インコーポレイテッド | がんを処置する方法 |
| EP4267129A1 (en) | 2020-12-22 | 2023-11-01 | IFM Due, Inc. | Methods of treating cancer |
| EP4274824A1 (en) | 2021-01-08 | 2023-11-15 | IFM Due, Inc. | Heterobicyclic compounds having an urea or analogue and their compositions for treating conditions associated with sting activity |
| JP2024502470A (ja) * | 2021-01-08 | 2024-01-19 | アイエフエム デュー インコーポレイテッド | Ｓｔｉｎｇ活性に関連する状態を治療するための化合物および組成物 |
| CN116981668A (zh) * | 2021-04-09 | 2023-10-31 | 百济神州(北京)生物科技有限公司 | 制备bcl-2抑制剂的中间体的方法 |
| IL310724A (en) | 2021-08-10 | 2024-04-01 | Ifm Due Inc | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH STING ACTIVITY |
| WO2024064358A1 (en) | 2022-09-23 | 2024-03-28 | Ifm Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
| CN117756698A (zh) * | 2022-12-16 | 2024-03-26 | 中国药科大学 | 脲类化合物及其作为sting抑制剂的医药用途 |
| CN116023321B (zh) * | 2022-12-30 | 2024-11-29 | 中国药科大学 | Sting抑制剂前药及其医药用途 |
| CN120794982A (zh) * | 2024-05-14 | 2025-10-17 | 中国药科大学 | 吡唑类sting抑制剂及其医药用途 |
| CN120794957A (zh) * | 2024-05-14 | 2025-10-17 | 中国药科大学 | 苯并含氮杂环类sting抑制剂及其医药用途 |
| WO2026023667A1 (ja) * | 2024-07-25 | 2026-01-29 | カルナバイオサイエンス株式会社 | フェニルピペラジン誘導体 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5783558A (en) * | 1980-11-13 | 1982-05-25 | Asahi Chem Ind Co Ltd | Novel organic compound and its preparation |
| JPS5783557A (en) * | 1980-11-14 | 1982-05-25 | Asahi Chem Ind Co Ltd | Novel azomethine compound and its preparation |
| US20120046290A1 (en) * | 1997-12-22 | 2012-02-23 | Jacques Dumas | Inhibition of p38 kinase activity using substituted heterocyclic ureas |
| BR0212841A (pt) | 2001-09-26 | 2004-08-03 | Pharmacia Italia Spa | Derivado ativo de aminoindazole como inibidores de cinase, processo para sua preparação e composições farmacêuticas que os contém |
| US7927613B2 (en) | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
| DE102005038947A1 (de) | 2005-05-18 | 2006-11-30 | Grünenthal GmbH | Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln |
| US8188113B2 (en) | 2006-09-14 | 2012-05-29 | Deciphera Pharmaceuticals, Inc. | Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
| JP2013545740A (ja) | 2010-11-10 | 2013-12-26 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | バニロイド受容体リガンドとしての置換された複素芳香族カルボキサミド誘導体および尿素誘導体 |
| US8497285B2 (en) | 2010-12-03 | 2013-07-30 | The Trustees Of The University Of Pennsylvania | Therapy of autoimmune colitis using a TIP60 inhibitor |
| CN102516153B (zh) | 2011-12-14 | 2014-03-12 | 南京工业大学 | 5-氟吲哚-2-酮-3-脲类化合物及其制备方法和应用 |
| CA2914815A1 (en) | 2013-06-11 | 2014-12-18 | Kala Pharmaceuticals, Inc. | Urea derivatives and uses thereof |
| CA2927009C (en) | 2013-10-21 | 2019-04-23 | Drexel University | Use of sting agonists to treat chronic hepatitis b virus infection |
| CN107417478B (zh) | 2017-06-05 | 2020-05-05 | 南京师范大学 | 一种催化氧化羰基化合成不对称二取代脲的方法 |
| EP3556362A1 (en) | 2018-04-16 | 2019-10-23 | Ecole Polytechnique Federale De Lausanne (Epfl) | Sting inhibitors |
| US20220160705A1 (en) * | 2019-03-20 | 2022-05-26 | Cornell University | Methods for controlling prostaglandin-mediated biological processes |
| EP4267129A1 (en) * | 2020-12-22 | 2023-11-01 | IFM Due, Inc. | Methods of treating cancer |
| US20240060982A1 (en) * | 2020-12-22 | 2024-02-22 | Ifm Due, Inc. | Methods of treating cancer |
| JP2024500874A (ja) * | 2020-12-22 | 2024-01-10 | アイエフエム デュー インコーポレイテッド | がんを処置する方法 |
| EP4267128A1 (en) * | 2020-12-22 | 2023-11-01 | IFM Due, Inc. | Methods of treating cancer |
-
2020
- 2020-12-30 CN CN202080097901.0A patent/CN115348957B/zh active Active
- 2020-12-30 PY PY202002089159A patent/PY2089159A/es unknown
- 2020-12-30 JP JP2022540328A patent/JP7756643B2/ja active Active
- 2020-12-30 WO PCT/US2020/067483 patent/WO2021138434A1/en not_active Ceased
- 2020-12-30 CN CN202511145327.2A patent/CN120965654A/zh active Pending
- 2020-12-30 UY UY0001039006A patent/UY39006A/es unknown
- 2020-12-30 TW TW109146905A patent/TW202136239A/zh unknown
- 2020-12-30 EP EP20845545.1A patent/EP4085051A1/en active Pending
- 2020-12-30 US US17/789,694 patent/US20230127839A1/en active Pending
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