JP2024512553A5 - - Google Patents
Info
- Publication number
- JP2024512553A5 JP2024512553A5 JP2023558325A JP2023558325A JP2024512553A5 JP 2024512553 A5 JP2024512553 A5 JP 2024512553A5 JP 2023558325 A JP2023558325 A JP 2023558325A JP 2023558325 A JP2023558325 A JP 2023558325A JP 2024512553 A5 JP2024512553 A5 JP 2024512553A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- dimethanobenzo
- hexahydro
- anneren
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21382237.2 | 2021-03-24 | ||
| EP21382237.2A EP4063348A1 (en) | 2021-03-24 | 2021-03-24 | Compounds as soluble epoxide hydrolase inhibitors |
| PCT/EP2022/056557 WO2022200105A1 (en) | 2021-03-24 | 2022-03-14 | Compounds as soluble epoxide hydrolase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024512553A JP2024512553A (ja) | 2024-03-19 |
| JP2024512553A5 true JP2024512553A5 (enExample) | 2025-03-18 |
Family
ID=75223297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023558325A Pending JP2024512553A (ja) | 2021-03-24 | 2022-03-14 | 可溶性エポキシドヒドロラーゼ阻害剤としての化合物 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20240182406A1 (enExample) |
| EP (2) | EP4063348A1 (enExample) |
| JP (1) | JP2024512553A (enExample) |
| CN (1) | CN118019728A (enExample) |
| WO (1) | WO2022200105A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024105225A1 (en) | 2022-11-18 | 2024-05-23 | Universitat De Barcelona | Synergistic combinations of a sigma receptor 1 (s1r) antagonist and a soluble epoxide hydrolase inhibitor (sehi) and their use in the treatment of pain |
| CN117731650A (zh) * | 2023-12-19 | 2024-03-22 | 重庆医科大学 | 一种防治高糖饮食所致肠损伤的方法及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2210799A1 (de) | 1972-03-07 | 1973-09-20 | Basf Ag | 5,9:7,11-dimethano-8-hetero-11h-5,6. 7.8.9.10-hexahydro-benzo-cyclononene |
| DE2261637A1 (de) | 1972-12-16 | 1974-06-20 | Basf Ag | 5,8 : 7.10-dimethano-5.6.7.8.9.10-hexa-hydro-benzo-cyclooctene und verfahren zu ihrer herstellung |
| WO2000023060A2 (en) | 1998-10-20 | 2000-04-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method of treating immunological disorders mediated by t-lymphocytes |
| DE60222264T2 (de) | 2001-06-29 | 2008-01-03 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Phenylpyrazolderivate als seh-inhibitoren |
| WO2007009001A1 (en) | 2005-07-12 | 2007-01-18 | The Regents Of The University Of California | Use of cis-epoxyeicosatrienoic acids and inhibitors of soluble epoxide hydrolase to alleviate eye disorders |
| US7851474B2 (en) | 2005-08-02 | 2010-12-14 | Neurogen Corporation | Dipiperazinyl ketones and related analogues |
| AR059826A1 (es) | 2006-03-13 | 2008-04-30 | Univ California | Inhibidores de urea conformacionalmente restringidos de epoxido hidrolasa soluble |
| BRPI0721451A2 (pt) * | 2007-03-13 | 2014-03-25 | Arete Therapeutics Inc | Compostos de 4-piperidiniluréia como inibidores de epóxido hidrolase solúvel |
| WO2009086426A2 (en) * | 2007-12-28 | 2009-07-09 | Arete Therapeutics, Inc. | Soluble epoxide hydrolase inhibitors for the treatment of endothelial dysfunction |
| WO2010025043A1 (en) * | 2008-08-29 | 2010-03-04 | Arete Therapeutics, Inc. | Use of soluble epoxide hydrolase inhibitors in the treatment of inflammatory vascular diseases |
| EP2809650B1 (en) | 2012-02-01 | 2018-04-11 | The Regents of The University of California | Acyl piperidine inhibitors of soluble epoxide hydrolase |
| DK3129023T3 (da) | 2014-03-27 | 2021-05-25 | Eicosis Llc | Potente opløselige epoxidhydrolase-inhibitorer |
| US10813894B2 (en) | 2015-02-20 | 2020-10-27 | The Regents Of The University Of California | Methods of inhibiting pain |
| BR112018001816A2 (en) | 2015-07-28 | 2018-09-18 | Universitat De Barcelona | Adamantil Urea Analogs As Soluble Inhibitors Of Epoxide Hydrolase |
| WO2017120012A1 (en) | 2016-01-05 | 2017-07-13 | The Regents Of The University Of California | Methods of treating mental disorders |
| EP3584236A1 (en) | 2018-06-20 | 2019-12-25 | Universitat de Barcelona | Polycyclic compounds soluble epoxide hydrolase inhibitors |
| WO2020146770A1 (en) | 2019-01-11 | 2020-07-16 | Beth Israel Deaconess Medical Center, Inc. | Methods for the prevention or treatment of cytokine storm, and for preventing diseases or conditions caused by cytokine storm |
-
2021
- 2021-03-24 EP EP21382237.2A patent/EP4063348A1/en not_active Withdrawn
-
2022
- 2022-03-14 CN CN202280037466.1A patent/CN118019728A/zh active Pending
- 2022-03-14 JP JP2023558325A patent/JP2024512553A/ja active Pending
- 2022-03-14 EP EP22712937.6A patent/EP4313947A1/en active Pending
- 2022-03-14 WO PCT/EP2022/056557 patent/WO2022200105A1/en not_active Ceased
- 2022-03-14 US US18/552,146 patent/US20240182406A1/en not_active Abandoned
-
2024
- 2024-10-14 US US18/915,070 patent/US12486222B2/en active Active
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