JP2021535895A5 - - Google Patents
Info
- Publication number
- JP2021535895A5 JP2021535895A5 JP2020570515A JP2020570515A JP2021535895A5 JP 2021535895 A5 JP2021535895 A5 JP 2021535895A5 JP 2020570515 A JP2020570515 A JP 2020570515A JP 2020570515 A JP2020570515 A JP 2020570515A JP 2021535895 A5 JP2021535895 A5 JP 2021535895A5
- Authority
- JP
- Japan
- Prior art keywords
- dimethanobenzo
- hexahydro
- methyl
- urea
- annulen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18382445.7 | 2018-06-20 | ||
| EP18382445.7A EP3584236A1 (en) | 2018-06-20 | 2018-06-20 | Polycyclic compounds soluble epoxide hydrolase inhibitors |
| PCT/EP2019/066181 WO2019243414A1 (en) | 2018-06-20 | 2019-06-19 | Polycyclic compounds as soluble epoxide hydrolase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021535895A JP2021535895A (ja) | 2021-12-23 |
| JP2021535895A5 true JP2021535895A5 (enExample) | 2022-06-27 |
| JP7442828B2 JP7442828B2 (ja) | 2024-03-05 |
Family
ID=62784072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020570515A Active JP7442828B2 (ja) | 2018-06-20 | 2019-06-19 | 可溶性エポキシド加水分解酵素阻害剤としての多環式化合物 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20210261564A1 (enExample) |
| EP (2) | EP3584236A1 (enExample) |
| JP (1) | JP7442828B2 (enExample) |
| KR (1) | KR102806466B1 (enExample) |
| CN (1) | CN112888674B (enExample) |
| AU (1) | AU2019291034B2 (enExample) |
| BR (1) | BR112020026027A2 (enExample) |
| CA (1) | CA3104342A1 (enExample) |
| EA (1) | EA202190072A1 (enExample) |
| ES (1) | ES2975451T3 (enExample) |
| IL (1) | IL279496A (enExample) |
| MX (1) | MX2020014276A (enExample) |
| WO (1) | WO2019243414A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113831301B (zh) * | 2020-06-08 | 2023-06-06 | 沈阳药科大学 | 苯并噻唑类衍生物及其用途 |
| EP4063348A1 (en) | 2021-03-24 | 2022-09-28 | Universitat de Barcelona | Compounds as soluble epoxide hydrolase inhibitors |
| WO2024105225A1 (en) | 2022-11-18 | 2024-05-23 | Universitat De Barcelona | Synergistic combinations of a sigma receptor 1 (s1r) antagonist and a soluble epoxide hydrolase inhibitor (sehi) and their use in the treatment of pain |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2210799A1 (de) | 1972-03-07 | 1973-09-20 | Basf Ag | 5,9:7,11-dimethano-8-hetero-11h-5,6. 7.8.9.10-hexahydro-benzo-cyclononene |
| DE2261637A1 (de) * | 1972-12-16 | 1974-06-20 | Basf Ag | 5,8 : 7.10-dimethano-5.6.7.8.9.10-hexa-hydro-benzo-cyclooctene und verfahren zu ihrer herstellung |
| WO2000023060A2 (en) | 1998-10-20 | 2000-04-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method of treating immunological disorders mediated by t-lymphocytes |
| DE60222264T2 (de) | 2001-06-29 | 2008-01-03 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Phenylpyrazolderivate als seh-inhibitoren |
| WO2007009001A1 (en) | 2005-07-12 | 2007-01-18 | The Regents Of The University Of California | Use of cis-epoxyeicosatrienoic acids and inhibitors of soluble epoxide hydrolase to alleviate eye disorders |
| US7851474B2 (en) | 2005-08-02 | 2010-12-14 | Neurogen Corporation | Dipiperazinyl ketones and related analogues |
| AR059826A1 (es) * | 2006-03-13 | 2008-04-30 | Univ California | Inhibidores de urea conformacionalmente restringidos de epoxido hidrolasa soluble |
| BRPI0721451A2 (pt) * | 2007-03-13 | 2014-03-25 | Arete Therapeutics Inc | Compostos de 4-piperidiniluréia como inibidores de epóxido hidrolase solúvel |
| EP2809650B1 (en) * | 2012-02-01 | 2018-04-11 | The Regents of The University of California | Acyl piperidine inhibitors of soluble epoxide hydrolase |
| US10813894B2 (en) | 2015-02-20 | 2020-10-27 | The Regents Of The University Of California | Methods of inhibiting pain |
| BR112018001816A2 (en) * | 2015-07-28 | 2018-09-18 | Universitat De Barcelona | Adamantil Urea Analogs As Soluble Inhibitors Of Epoxide Hydrolase |
| WO2017120012A1 (en) | 2016-01-05 | 2017-07-13 | The Regents Of The University Of California | Methods of treating mental disorders |
-
2018
- 2018-06-20 EP EP18382445.7A patent/EP3584236A1/en not_active Withdrawn
-
2019
- 2019-06-19 AU AU2019291034A patent/AU2019291034B2/en active Active
- 2019-06-19 EA EA202190072A patent/EA202190072A1/ru unknown
- 2019-06-19 BR BR112020026027-4A patent/BR112020026027A2/pt not_active Application Discontinuation
- 2019-06-19 CN CN201980048385.XA patent/CN112888674B/zh active Active
- 2019-06-19 CA CA3104342A patent/CA3104342A1/en active Pending
- 2019-06-19 ES ES19731287T patent/ES2975451T3/es active Active
- 2019-06-19 KR KR1020217001663A patent/KR102806466B1/ko active Active
- 2019-06-19 JP JP2020570515A patent/JP7442828B2/ja active Active
- 2019-06-19 WO PCT/EP2019/066181 patent/WO2019243414A1/en not_active Ceased
- 2019-06-19 US US17/253,041 patent/US20210261564A1/en not_active Abandoned
- 2019-06-19 MX MX2020014276A patent/MX2020014276A/es unknown
- 2019-06-19 EP EP19731287.9A patent/EP3810572B1/en active Active
-
2020
- 2020-12-16 IL IL279496A patent/IL279496A/en unknown
-
2024
- 2024-08-08 US US18/798,430 patent/US20240400575A1/en active Pending
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