JP2024509917A5 - - Google Patents

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Publication number
JP2024509917A5
JP2024509917A5 JP2023555231A JP2023555231A JP2024509917A5 JP 2024509917 A5 JP2024509917 A5 JP 2024509917A5 JP 2023555231 A JP2023555231 A JP 2023555231A JP 2023555231 A JP2023555231 A JP 2023555231A JP 2024509917 A5 JP2024509917 A5 JP 2024509917A5
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JP
Japan
Prior art keywords
domain
pharmaceutical composition
antigen
orthogonal
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023555231A
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English (en)
Japanese (ja)
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JP2024509917A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/019479 external-priority patent/WO2022192346A1/en
Publication of JP2024509917A publication Critical patent/JP2024509917A/ja
Publication of JP2024509917A5 publication Critical patent/JP2024509917A5/ja
Pending legal-status Critical Current

Links

JP2023555231A 2021-03-09 2022-03-09 腫瘍溶解性ウイルスによる直交性il-2の送達を用いた、固形腫瘍におけるt細胞の選択的刺激方法 Pending JP2024509917A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163158671P 2021-03-09 2021-03-09
US63/158,671 2021-03-09
PCT/US2022/019479 WO2022192346A1 (en) 2021-03-09 2022-03-09 Selective stimulation of t cells in solid tumors using oncolytic viral delivery of orthogonal il-2

Publications (2)

Publication Number Publication Date
JP2024509917A JP2024509917A (ja) 2024-03-05
JP2024509917A5 true JP2024509917A5 (https=) 2025-03-12

Family

ID=83227027

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023555231A Pending JP2024509917A (ja) 2021-03-09 2022-03-09 腫瘍溶解性ウイルスによる直交性il-2の送達を用いた、固形腫瘍におけるt細胞の選択的刺激方法

Country Status (5)

Country Link
US (1) US20240299541A1 (https=)
EP (1) EP4305054A4 (https=)
JP (1) JP2024509917A (https=)
CN (1) CN117377682A (https=)
WO (1) WO2022192346A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022348588A1 (en) 2021-09-17 2024-04-04 Parker Institute For Cancer Immunotherapy Switch receptors using il-9 signaling domains
EP4402160A4 (en) * 2021-09-17 2025-11-19 Univ Pennsylvania CHIMERIC ANTIGENIC RECEPTORS COMPRISING AN INTERLEUKIN-9 RECEPTOR SIGNALING DOMAIN
WO2024015988A1 (en) * 2022-07-15 2024-01-18 The Regents Of The University Of California Il-9r signaling compositions and method
CN120225568A (zh) * 2022-12-27 2025-06-27 广州瑞风生物科技有限公司 一种融合蛋白及其应用
WO2025085721A1 (en) * 2023-10-18 2025-04-24 Memorial Sloan-Kettering Cancer Center Chimeric receptors and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117659160A (zh) * 2015-09-11 2024-03-08 小利兰·斯坦福大学托管委员会 生物相关正交细胞因子/受体对
AU2019215031C1 (en) * 2018-01-31 2026-02-26 Novartis Ag Combination therapy using a chimeric antigen receptor
WO2020163634A1 (en) * 2019-02-08 2020-08-13 Seattle Children's Hospital (dba Seattle Children's Research Institute) Chimeric cytokine receptors
CA3179414A1 (en) * 2020-04-06 2021-10-14 Synthekine, Inc. Human immune cells genomically modified to express orthogonal receptors

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