JP2024509917A - 腫瘍溶解性ウイルスによる直交性il-2の送達を用いた、固形腫瘍におけるt細胞の選択的刺激方法 - Google Patents

腫瘍溶解性ウイルスによる直交性il-2の送達を用いた、固形腫瘍におけるt細胞の選択的刺激方法 Download PDF

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JP2024509917A
JP2024509917A JP2023555231A JP2023555231A JP2024509917A JP 2024509917 A JP2024509917 A JP 2024509917A JP 2023555231 A JP2023555231 A JP 2023555231A JP 2023555231 A JP2023555231 A JP 2023555231A JP 2024509917 A JP2024509917 A JP 2024509917A
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ミッコ シウララ
カール エイチ. ジューン
エイブリー ポージー
アントニ リバス
アヌシャ カルバシ
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University of California San Diego UCSD
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JP2023555231A 2021-03-09 2022-03-09 腫瘍溶解性ウイルスによる直交性il-2の送達を用いた、固形腫瘍におけるt細胞の選択的刺激方法 Pending JP2024509917A (ja)

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US202163158671P 2021-03-09 2021-03-09
US63/158,671 2021-03-09
PCT/US2022/019479 WO2022192346A1 (en) 2021-03-09 2022-03-09 Selective stimulation of t cells in solid tumors using oncolytic viral delivery of orthogonal il-2

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WO2023044457A1 (en) 2021-09-17 2023-03-23 Parker Institute For Cancer Immunotherapy Switch receptors using il-9 signaling domains
US20230265147A1 (en) * 2021-09-17 2023-08-24 The Trustees Of The University Of Pennsylvania Interleukin-9 Signaling in Chimeric Antigen Receptor (CAR) Immune Cells
EP4554611A1 (en) * 2022-07-15 2025-05-21 The Regents Of The University Of California Il-9r signaling compositions and methods
CN120225568A (zh) * 2022-12-27 2025-06-27 广州瑞风生物科技有限公司 一种融合蛋白及其应用
WO2025085721A1 (en) * 2023-10-18 2025-04-24 Memorial Sloan-Kettering Cancer Center Chimeric receptors and uses thereof

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WO2019152660A1 (en) * 2018-01-31 2019-08-08 Novartis Ag Combination therapy using a chimeric antigen receptor
WO2019173773A1 (en) * 2015-09-11 2019-09-12 The Board Of Trustees Of The Leland Stanford Junior University Biologically relevant orthogonal cytokine/receptor pairs
WO2020163634A1 (en) * 2019-02-08 2020-08-13 Seattle Children's Hospital (dba Seattle Children's Research Institute) Chimeric cytokine receptors

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CN115996746A (zh) * 2020-04-06 2023-04-21 辛德凯因股份有限公司 经基因组修饰以表达正交受体的人免疫细胞

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WO2019173773A1 (en) * 2015-09-11 2019-09-12 The Board Of Trustees Of The Leland Stanford Junior University Biologically relevant orthogonal cytokine/receptor pairs
WO2019152660A1 (en) * 2018-01-31 2019-08-08 Novartis Ag Combination therapy using a chimeric antigen receptor
WO2020163634A1 (en) * 2019-02-08 2020-08-13 Seattle Children's Hospital (dba Seattle Children's Research Institute) Chimeric cytokine receptors

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CANCER BIOLOGY & THERAPY, vol. 21, no. 6, JPN6026001144, 2020, pages 570 - 580, ISSN: 0005772373 *
MOL. CANCER THER., vol. Vol. 8, No. 12 Suppl., JPN6026001146, 2009, pages 242, ISSN: 0005772375 *
SCIENCE, vol. 359, JPN6026001145, 2018, pages 1037 - 1042, ISSN: 0005772374 *

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