JP2021519580A5 - - Google Patents
Info
- Publication number
- JP2021519580A5 JP2021519580A5 JP2020552225A JP2020552225A JP2021519580A5 JP 2021519580 A5 JP2021519580 A5 JP 2021519580A5 JP 2020552225 A JP2020552225 A JP 2020552225A JP 2020552225 A JP2020552225 A JP 2020552225A JP 2021519580 A5 JP2021519580 A5 JP 2021519580A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- domain containing
- signaling domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862649499P | 2018-03-28 | 2018-03-28 | |
| US62/649,499 | 2018-03-28 | ||
| PCT/US2019/024441 WO2019191339A1 (en) | 2018-03-28 | 2019-03-27 | Expression vectors for chimeric engulfment receptors, genetically modified host cells, and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021519580A JP2021519580A (ja) | 2021-08-12 |
| JP2021519580A5 true JP2021519580A5 (https=) | 2022-04-04 |
| JP7549533B2 JP7549533B2 (ja) | 2024-09-11 |
Family
ID=66626002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020552225A Active JP7549533B2 (ja) | 2018-03-28 | 2019-03-27 | キメラ貪食受容体のための発現ベクター、遺伝子改変宿主細胞およびそれらの使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20210024607A1 (https=) |
| EP (1) | EP3774869A1 (https=) |
| JP (1) | JP7549533B2 (https=) |
| KR (1) | KR20210024441A (https=) |
| CN (1) | CN112218886B (https=) |
| AU (1) | AU2019243153A1 (https=) |
| CA (1) | CA3093969A1 (https=) |
| IL (1) | IL277587A (https=) |
| MX (1) | MX2020010235A (https=) |
| RU (1) | RU2020135106A (https=) |
| WO (1) | WO2019191339A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017335634A1 (en) | 2016-09-27 | 2019-03-14 | Cero Therapeutics, Inc. | Chimeric engulfment receptor molecules |
| EP4714966A2 (en) | 2017-09-26 | 2026-03-25 | Cero Therapeutics Holdings, Inc. | Chimeric engulfment receptor molecules and methods of use |
| EP3774906A1 (en) | 2018-03-28 | 2021-02-17 | Cero Therapeutics, Inc. | Chimeric tim4 receptors and uses thereof |
| MX2020010241A (es) | 2018-03-28 | 2020-10-16 | Cero Therapeutics Inc | Composiciones de inmunoterapia celular y usos de las mismas. |
| EP4038097A1 (en) | 2019-10-03 | 2022-08-10 | Cero Therapeutics, Inc. | Chimeric tim4 receptors and uses thereof |
| WO2021217087A1 (en) * | 2020-04-23 | 2021-10-28 | The Regents Of The University Of California | Genetically engineered phagocytes, and related compositions, vectors, methods and systems |
| WO2022036287A1 (en) | 2020-08-14 | 2022-02-17 | Cero Therapeutics, Inc. | Anti-cd72 chimeric receptors and uses thereof |
| WO2022036285A1 (en) | 2020-08-14 | 2022-02-17 | Cero Therapeutics, Inc. | Compositions and methods for treating cancer with chimeric tim receptors in combination with inhibitors of poly (adp-ribose) polymerase |
| WO2022036265A1 (en) | 2020-08-14 | 2022-02-17 | Cero Therapeutics, Inc. | Chimeric tim receptors and uses thereof |
| CA3189328A1 (en) * | 2020-08-14 | 2022-02-17 | Cero Therapeutics, Inc. | Chimeric tim receptors and uses thereof |
| CN112194726B (zh) * | 2020-09-02 | 2023-06-23 | 沣潮医药科技（上海）有限公司 | 用于病理性蛋白聚集物清除的嵌合抗原受体及其应用 |
| CN116916940A (zh) * | 2020-11-04 | 2023-10-20 | 美洛德生物医药公司 | 工程化嵌合融合蛋白组合物及其使用方法 |
| EP4240367A4 (en) * | 2020-11-04 | 2024-10-16 | Myeloid Therapeutics, Inc. | MODIFIED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF |
| EP4247856A4 (en) * | 2020-11-18 | 2024-10-30 | Carina Biotech Pty Ltd | CHIMERIC ANTIGEN RECEPTOR T CELL AND METHODS |
| WO2022197974A1 (en) * | 2021-03-18 | 2022-09-22 | University Of Florida Research Foundation, Incorporated | Chimeric phagocytic receptors for treatment of neurodegenerative disorders |
| US20240366762A1 (en) * | 2021-04-28 | 2024-11-07 | Sanquin IP B.V. | Chimeric fc-alpha receptors and uses thereof |
| WO2022234976A1 (ko) * | 2021-05-04 | 2022-11-10 | 주식회사 이뮤노로지컬디자이닝랩 | 키메릭 항원 수용체(car)를 포함하는 형질전환된 항원 특이적 전문적 항원표출세포 및 이의 용도 |
| WO2023286088A1 (en) * | 2021-07-16 | 2023-01-19 | Indian Institute Of Science Education And Research Bhopal | Methods and compositions for viral vector transduction |
| EP4376874B1 (en) | 2021-07-28 | 2026-03-04 | Cero Therapeutics Holdings, Inc. | Chimeric tim4 receptors and uses thereof |
| US20240408204A1 (en) * | 2021-10-28 | 2024-12-12 | The Regents Of The University Of California | Methods of Treating Lymphoma with a Phagocyte Having a Chimeric Antigen Receptor |
| KR20250029302A (ko) * | 2022-03-01 | 2025-03-04 | 헤모제닉스 파마슈티컬스 엘엘씨 | 키메라 미끼 수용체 및 이의 용도 |
| US20250195573A1 (en) * | 2022-03-18 | 2025-06-19 | The Regents Of The University Of Colorado, A Body Corporate | Genetically engineered t-cell co-receptors and methods of use thereof |
| CN114806912A (zh) * | 2022-04-06 | 2022-07-29 | 中国海洋大学 | 高效表达菌丝霉素的重组工程菌及其应用 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5283173A (en) | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| NZ243082A (en) | 1991-06-28 | 1995-02-24 | Ici Plc | 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof |
| GB9300059D0 (en) | 1992-01-20 | 1993-03-03 | Zeneca Ltd | Quinazoline derivatives |
| TW225528B (https=) | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
| GB9508538D0 (en) | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| US5747498A (en) | 1996-05-28 | 1998-05-05 | Pfizer Inc. | Alkynyl and azido-substituted 4-anilinoquinazolines |
| SI9620103A (sl) | 1995-07-06 | 1998-10-31 | Novartis Ag | Pirolopirimidini in postopki za njihovo pripravo |
| GB9518220D0 (en) | 1995-09-06 | 1995-11-08 | Medical Res Council | Checkpoint gene |
| US5760041A (en) | 1996-02-05 | 1998-06-02 | American Cyanamid Company | 4-aminoquinazoline EGFR Inhibitors |
| GB9603095D0 (en) | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline derivatives |
| EA001595B1 (ru) | 1996-04-12 | 2001-06-25 | Варнер-Ламберт Компани | Необратимые ингибиторы тирозинкиназ |
| CA2258548C (en) | 1996-06-24 | 2005-07-26 | Pfizer Inc. | Phenylamino-substituted tricyclic derivatives for treatment of hyperproliferative diseases |
| EP0954315A2 (en) | 1996-09-13 | 1999-11-10 | Sugen, Inc. | Use of quinazoline derivatives for the manufacture of a medicament in the treatment of hyperproliferative skin disorders |
| EP0837063A1 (en) | 1996-10-17 | 1998-04-22 | Pfizer Inc. | 4-Aminoquinazoline derivatives |
| CO4940418A1 (es) | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| US6995162B2 (en) | 2001-01-12 | 2006-02-07 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
| US8709412B2 (en) * | 2001-06-29 | 2014-04-29 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of TIM receptor activity in combination with cytoreductive therapy |
| PT1478648E (pt) | 2002-02-01 | 2014-07-15 | Ariad Pharma Inc | Compostos contendo fósforo e suas utilizações |
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| JO2660B1 (en) | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
| US8119772B2 (en) | 2006-09-29 | 2012-02-21 | California Institute Of Technology | MART-1 T cell receptors |
| EP2205242B1 (en) | 2007-09-12 | 2015-04-15 | Genentech, Inc. | Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents, and methods of use |
| JP5348725B2 (ja) | 2007-10-25 | 2013-11-20 | ジェネンテック， インコーポレイテッド | チエノピリミジン化合物の製造方法 |
| US20130071414A1 (en) | 2011-04-27 | 2013-03-21 | Gianpietro Dotti | Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies |
| US10391126B2 (en) | 2011-11-18 | 2019-08-27 | Board Of Regents, The University Of Texas System | CAR+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA |
| BR122020002986A8 (pt) | 2012-08-20 | 2023-04-18 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Método e composições para imunoterapia celular |
| AU2013329186B2 (en) | 2012-10-10 | 2019-02-14 | Sangamo Therapeutics, Inc. | T cell modifying compounds and uses thereof |
| WO2015066262A1 (en) | 2013-11-04 | 2015-05-07 | Trustees Of Dartmouth College | Methods for preventing toxicity of adoptive cell therapy |
| MX375379B (es) | 2014-05-29 | 2025-03-06 | Us Health | Receptores de celulas t anti - papilomavirus 16 e7 humano. |
| EP4205749A1 (en) * | 2014-07-31 | 2023-07-05 | Novartis AG | Subset-optimized chimeric antigen receptor-containing cells |
| PL3298033T5 (pl) | 2015-05-18 | 2023-10-30 | TCR2 Therapeutics Inc. | Kompozycje i zastosowania medyczne do reprogramowania TCR z zastosowaniem białek fuzyjnych |
| IL315940A (en) * | 2015-07-28 | 2024-11-01 | Univ Pennsylvania | Altered monocytes/macrophages expressing chimeric antigen receptors and their uses |
| WO2018031419A1 (en) * | 2016-08-12 | 2018-02-15 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for enhancing immunogenic cross-presentation of tumor antigens |
| AU2017335634A1 (en) * | 2016-09-27 | 2019-03-14 | Cero Therapeutics, Inc. | Chimeric engulfment receptor molecules |
| WO2020097193A1 (en) * | 2018-11-06 | 2020-05-14 | The Regents Of The University Of California | Chimeric antigen receptors for phagocytosis |
-
2019
- 2019-03-27 CA CA3093969A patent/CA3093969A1/en active Pending
- 2019-03-27 MX MX2020010235A patent/MX2020010235A/es unknown
- 2019-03-27 JP JP2020552225A patent/JP7549533B2/ja active Active
- 2019-03-27 EP EP19725783.5A patent/EP3774869A1/en active Pending
- 2019-03-27 CN CN201980035719.XA patent/CN112218886B/zh active Active
- 2019-03-27 AU AU2019243153A patent/AU2019243153A1/en not_active Abandoned
- 2019-03-27 US US17/040,464 patent/US20210024607A1/en not_active Abandoned
- 2019-03-27 KR KR1020207029512A patent/KR20210024441A/ko not_active Ceased
- 2019-03-27 WO PCT/US2019/024441 patent/WO2019191339A1/en not_active Ceased
- 2019-03-27 RU RU2020135106A patent/RU2020135106A/ru unknown
-
2020
- 2020-09-24 IL IL277587A patent/IL277587A/en unknown
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