CN112218886B - 嵌合吞噬受体的表达载体、基因修饰的宿主细胞及其用途 - Google Patents

嵌合吞噬受体的表达载体、基因修饰的宿主细胞及其用途

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Publication number
CN112218886B
CN112218886B CN201980035719.XA CN201980035719A CN112218886B CN 112218886 B CN112218886 B CN 112218886B CN 201980035719 A CN201980035719 A CN 201980035719A CN 112218886 B CN112218886 B CN 112218886B
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CN112218886A (zh
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D·M·科瑞
I·伊巴拉
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Senluo Treatment Holdings Co ltd
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Senluo Treatment Holdings Co ltd
Cero Therapeutics Inc
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CN201980035719.XA 2018-03-28 2019-03-27 嵌合吞噬受体的表达载体、基因修饰的宿主细胞及其用途 Active CN112218886B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862649499P 2018-03-28 2018-03-28
US62/649,499 2018-03-28
PCT/US2019/024441 WO2019191339A1 (en) 2018-03-28 2019-03-27 Expression vectors for chimeric engulfment receptors, genetically modified host cells, and uses thereof

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CN112218886A CN112218886A (zh) 2021-01-12
CN112218886B true CN112218886B (zh) 2026-03-31

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US (1) US20210024607A1 (https=)
EP (1) EP3774869A1 (https=)
JP (1) JP7549533B2 (https=)
KR (1) KR20210024441A (https=)
CN (1) CN112218886B (https=)
AU (1) AU2019243153A1 (https=)
CA (1) CA3093969A1 (https=)
IL (1) IL277587A (https=)
MX (1) MX2020010235A (https=)
RU (1) RU2020135106A (https=)
WO (1) WO2019191339A1 (https=)

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EP4714966A2 (en) 2017-09-26 2026-03-25 Cero Therapeutics Holdings, Inc. Chimeric engulfment receptor molecules and methods of use
EP3774906A1 (en) 2018-03-28 2021-02-17 Cero Therapeutics, Inc. Chimeric tim4 receptors and uses thereof
MX2020010241A (es) 2018-03-28 2020-10-16 Cero Therapeutics Inc Composiciones de inmunoterapia celular y usos de las mismas.
EP4038097A1 (en) 2019-10-03 2022-08-10 Cero Therapeutics, Inc. Chimeric tim4 receptors and uses thereof
WO2021217087A1 (en) * 2020-04-23 2021-10-28 The Regents Of The University Of California Genetically engineered phagocytes, and related compositions, vectors, methods and systems
WO2022036287A1 (en) 2020-08-14 2022-02-17 Cero Therapeutics, Inc. Anti-cd72 chimeric receptors and uses thereof
WO2022036285A1 (en) 2020-08-14 2022-02-17 Cero Therapeutics, Inc. Compositions and methods for treating cancer with chimeric tim receptors in combination with inhibitors of poly (adp-ribose) polymerase
WO2022036265A1 (en) 2020-08-14 2022-02-17 Cero Therapeutics, Inc. Chimeric tim receptors and uses thereof
CA3189328A1 (en) * 2020-08-14 2022-02-17 Cero Therapeutics, Inc. Chimeric tim receptors and uses thereof
CN112194726B (zh) * 2020-09-02 2023-06-23 沣潮医药科技（上海）有限公司 用于病理性蛋白聚集物清除的嵌合抗原受体及其应用
CN116916940A (zh) * 2020-11-04 2023-10-20 美洛德生物医药公司 工程化嵌合融合蛋白组合物及其使用方法
EP4240367A4 (en) * 2020-11-04 2024-10-16 Myeloid Therapeutics, Inc. MODIFIED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF
EP4247856A4 (en) * 2020-11-18 2024-10-30 Carina Biotech Pty Ltd CHIMERIC ANTIGEN RECEPTOR T CELL AND METHODS
WO2022197974A1 (en) * 2021-03-18 2022-09-22 University Of Florida Research Foundation, Incorporated Chimeric phagocytic receptors for treatment of neurodegenerative disorders
US20240366762A1 (en) * 2021-04-28 2024-11-07 Sanquin IP B.V. Chimeric fc-alpha receptors and uses thereof
WO2022234976A1 (ko) * 2021-05-04 2022-11-10 주식회사 이뮤노로지컬디자이닝랩 키메릭 항원 수용체(car)를 포함하는 형질전환된 항원 특이적 전문적 항원표출세포 및 이의 용도
WO2023286088A1 (en) * 2021-07-16 2023-01-19 Indian Institute Of Science Education And Research Bhopal Methods and compositions for viral vector transduction
EP4376874B1 (en) 2021-07-28 2026-03-04 Cero Therapeutics Holdings, Inc. Chimeric tim4 receptors and uses thereof
US20240408204A1 (en) * 2021-10-28 2024-12-12 The Regents Of The University Of California Methods of Treating Lymphoma with a Phagocyte Having a Chimeric Antigen Receptor
KR20250029302A (ko) * 2022-03-01 2025-03-04 헤모제닉스 파마슈티컬스 엘엘씨 키메라 미끼 수용체 및 이의 용도
US20250195573A1 (en) * 2022-03-18 2025-06-19 The Regents Of The University Of Colorado, A Body Corporate Genetically engineered t-cell co-receptors and methods of use thereof
CN114806912A (zh) * 2022-04-06 2022-07-29 中国海洋大学 高效表达菌丝霉素的重组工程菌及其应用

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