JP2024505119A - 合成ポリヌクレオチド及び対立遺伝子を選択的に増幅する方法 - Google Patents

合成ポリヌクレオチド及び対立遺伝子を選択的に増幅する方法 Download PDF

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JP2024505119A
JP2024505119A JP2023571247A JP2023571247A JP2024505119A JP 2024505119 A JP2024505119 A JP 2024505119A JP 2023571247 A JP2023571247 A JP 2023571247A JP 2023571247 A JP2023571247 A JP 2023571247A JP 2024505119 A JP2024505119 A JP 2024505119A
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polynucleotide
optionally
residue
dna
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JP2024505119A5 (https=
JPWO2022169846A5 (https=
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ロディ，チャールズ
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ローディーエックス・インコーポレイテッド
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Publication of JP2024505119A5 publication Critical patent/JP2024505119A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP2023571247A 2021-02-02 2022-02-02 合成ポリヌクレオチド及び対立遺伝子を選択的に増幅する方法 Pending JP2024505119A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163144723P 2021-02-02 2021-02-02
US63/144,723 2021-02-02
PCT/US2022/014908 WO2022169846A1 (en) 2021-02-02 2022-02-02 Synthetic polynucleotides and methods for selectively amplifying alleles

Publications (3)

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JP2024505119A true JP2024505119A (ja) 2024-02-02
JP2024505119A5 JP2024505119A5 (https=) 2025-02-10
JPWO2022169846A5 JPWO2022169846A5 (https=) 2025-02-10

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JP2023571247A Pending JP2024505119A (ja) 2021-02-02 2022-02-02 合成ポリヌクレオチド及び対立遺伝子を選択的に増幅する方法

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Country Link
US (1) US20240301481A1 (https=)
EP (1) EP4288557A4 (https=)
JP (1) JP2024505119A (https=)
KR (1) KR20230141826A (https=)
CN (1) CN116888271A (https=)
AU (1) AU2022216246A1 (https=)
CA (1) CA3206960A1 (https=)
WO (1) WO2022169846A1 (https=)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11513881A (ja) * 1995-06-07 1999-11-30 ジェン−プロープ・インコーポレーテッド テンプレートおよびプライマーに基づく酵素的に切断可能なオリゴヌクレオチドの合成
JP2011530301A (ja) * 2008-08-12 2011-12-22 エフ．ホフマン−ラ ロシュ アーゲー プルーフリーディング・プライマー伸長

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5916777A (en) * 1995-06-07 1999-06-29 Gen-Probe Incorporated Enzymatic synthesis of oligonucleotides using 3'-ribonucleotide primers
CN1254548C (zh) * 2000-08-23 2006-05-03 宝生物工程株式会社 核酸扩增方法
WO2002064833A1 (en) * 2001-02-15 2002-08-22 Takara Bio Inc. Method of detecting nucleotide polymorphism
US10227641B2 (en) * 2008-04-30 2019-03-12 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
WO2011085075A2 (en) * 2010-01-07 2011-07-14 Gen9, Inc. Assembly of high fidelity polynucleotides
CA2863808C (en) * 2012-02-20 2020-07-21 Speedx Pty Ltd Methods and oligonucleotides for amplifying and/or detecting nucleic acids
UA116205C2 (uk) * 2012-04-09 2018-02-26 Енвіролоджикс Інк. Спосіб кількісного визначення послідовності нуклеїнової кислоти в зразку
WO2017142989A1 (en) * 2016-02-17 2017-08-24 Admera Health LLC Nucleic acid preparation and analysis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11513881A (ja) * 1995-06-07 1999-11-30 ジェン−プロープ・インコーポレーテッド テンプレートおよびプライマーに基づく酵素的に切断可能なオリゴヌクレオチドの合成
JP2011530301A (ja) * 2008-08-12 2011-12-22 エフ．ホフマン−ラ ロシュ アーゲー プルーフリーディング・プライマー伸長

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Publication number Publication date
EP4288557A4 (en) 2024-12-25
EP4288557A1 (en) 2023-12-13
CA3206960A1 (en) 2022-08-11
WO2022169846A1 (en) 2022-08-11
AU2022216246A1 (en) 2023-09-14
KR20230141826A (ko) 2023-10-10
US20240301481A1 (en) 2024-09-12
CN116888271A (zh) 2023-10-13

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