JP2024505027A5 - - Google Patents
Info
- Publication number
- JP2024505027A5 JP2024505027A5 JP2023545204A JP2023545204A JP2024505027A5 JP 2024505027 A5 JP2024505027 A5 JP 2024505027A5 JP 2023545204 A JP2023545204 A JP 2023545204A JP 2023545204 A JP2023545204 A JP 2023545204A JP 2024505027 A5 JP2024505027 A5 JP 2024505027A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- sequence described
- enhancer
- expression construct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163144743P | 2021-02-02 | 2021-02-02 | |
| US63/144,743 | 2021-02-02 | ||
| PCT/US2022/014956 WO2022169884A2 (en) | 2021-02-02 | 2022-02-02 | Artificial expression constructs for modulating gene expression in gabaergic neurons and astrocytes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024505027A JP2024505027A (ja) | 2024-02-02 |
| JP2024505027A5 true JP2024505027A5 (https=) | 2025-02-10 |
Family
ID=82742483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023545204A Pending JP2024505027A (ja) | 2021-02-02 | 2022-02-02 | Ｇａｂａ作動性ニューロン及び星状膠細胞における遺伝子発現の調節のための人工発現構築物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240117377A1 (https=) |
| EP (1) | EP4288064A4 (https=) |
| JP (1) | JP2024505027A (https=) |
| AU (1) | AU2022217778A1 (https=) |
| CA (1) | CA3207224A1 (https=) |
| WO (1) | WO2022169884A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2024293430A1 (en) * | 2023-07-18 | 2025-12-11 | Allen Institute | Antisense oligonucleotides and artificial expression constructs for expressing rna in inhibitory neurons |
| AU2024346721A1 (en) * | 2023-09-18 | 2026-04-09 | Allen Institute | Artificial expression constructs for modulating gene expression in neurons and astrocytes for the assessment and/or treatment of slc6a1-related disorders |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2568689A1 (en) * | 2004-06-04 | 2005-12-15 | Fluxome Sciences A/S | Metabolically engineered cells for the production of polyunsaturated fatty acids |
| WO2006090288A2 (en) * | 2005-02-28 | 2006-08-31 | Integragen | Human autism susceptibility genes encoding a neurotransmitter transporter and uses thereof |
| CA2817256A1 (en) * | 2010-11-12 | 2012-05-18 | The General Hospital Corporation | Polycomb-associated non-coding rnas |
| WO2013155222A2 (en) * | 2012-04-10 | 2013-10-17 | The Regents Of The University Of California | Brain-specific enhancers for cell-based therapy |
| ES2833230T3 (es) * | 2014-05-13 | 2021-06-14 | Univ Pennsylvania | Composiciones que comprenden AVV que expresan construcciones y usos de doble anticuerpo del mismo |
| EP4653536A3 (en) * | 2017-03-17 | 2026-02-25 | Adverum Biotechnologies, Inc. | Compositions and methods for enhanced gene expression |
| CA3096407A1 (en) * | 2018-04-09 | 2019-10-17 | Allen Institute | Rescuing voltage-gated sodium channel function in inhibitory neurons |
| WO2020076614A1 (en) * | 2018-10-08 | 2020-04-16 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in interneurons |
| CA3173609A1 (en) * | 2020-03-27 | 2021-09-30 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in non-neuronal brain cells |
-
2022
- 2022-02-02 AU AU2022217778A patent/AU2022217778A1/en active Pending
- 2022-02-02 CA CA3207224A patent/CA3207224A1/en active Pending
- 2022-02-02 EP EP22750333.1A patent/EP4288064A4/en active Pending
- 2022-02-02 WO PCT/US2022/014956 patent/WO2022169884A2/en not_active Ceased
- 2022-02-02 US US18/263,930 patent/US20240117377A1/en active Pending
- 2022-02-02 JP JP2023545204A patent/JP2024505027A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022513339A5 (https=) | ||
| AU2017313917B2 (en) | CRISPR-Cas genome engineering via a modular AAV delivery system | |
| CN102741405B (zh) | 提高基因表达的系统和保持有该系统的载体 | |
| US20190315642A1 (en) | Compositions for in vivo Expression of Therapeutic Sequences in the Microbiome | |
| ES2223051T3 (es) | Vectores de adnc de alfavirus. | |
| CN112040988A (zh) | 修饰的aav衣壳多肽用于治疗肌肉疾病 | |
| JP2025023947A5 (https=) | ||
| JP2026021360A5 (https=) | ||
| JP6949184B2 (ja) | 治療的な使用のための、核酸送達のための治療用ファージおよび方法 | |
| Lescan et al. | De novo synthesis of elastin by exogenous delivery of synthetic modified mRNA into skin and elastin-deficient cells | |
| KR102602486B1 (ko) | 신형 천연 단백질 및 그의 응용 | |
| JP2024505027A5 (https=) | ||
| KR20230131229A (ko) | 부위 특이적 유전자 변형 | |
| WO1995027069A1 (en) | Alphavirus rna as carrier for vaccines | |
| CN109666973B (zh) | 一种穿过血脑屏障的肽库及其筛选方法 | |
| CN108676097B (zh) | 一种靶向肿瘤细胞的嵌合肽或嵌合蛋白及其应用 | |
| CN104592381A (zh) | 一种利拉鲁肽中间体多肽的制备方法 | |
| JP2023518980A5 (https=) | ||
| CN113121651A (zh) | 新型低中和抗体腺相关病毒衣壳蛋白 | |
| AU2022368453A1 (en) | Chimeric betacoronavirus spike polypeptides | |
| JP2024519955A5 (https=) | ||
| CN113121654A (zh) | 新型腺相关病毒衣壳蛋白及包含其的新型腺相关病毒载体 | |
| JP2023529833A5 (https=) | ||
| JP2015203014A (ja) | 脊髄組織標的化ペプチド及びその利用 | |
| CN119161495B (zh) | 呼吸道合胞病毒重构多肽及其应用 |