AU2022217778A1 - Artificial expression constructs for modulating gene expression in gabaergic neurons and astrocytes - Google Patents

Artificial expression constructs for modulating gene expression in gabaergic neurons and astrocytes Download PDF

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AU2022217778A1
AU2022217778A1 AU2022217778A AU2022217778A AU2022217778A1 AU 2022217778 A1 AU2022217778 A1 AU 2022217778A1 AU 2022217778 A AU2022217778 A AU 2022217778A AU 2022217778 A AU2022217778 A AU 2022217778A AU 2022217778 A1 AU2022217778 A1 AU 2022217778A1
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seq
ehgt
expression construct
enhancer
artificial expression
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AU2022217778A9 (en
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Bryan GORE
Edward Sebastian LEIN
Boaz P. LEVI
Deja MACHEN
Refugio MARTINEZ
John K. Mich
Jonathan Ting
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Allen Institute
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Allen Institute
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AU2022217778A 2021-02-02 2022-02-02 Artificial expression constructs for modulating gene expression in gabaergic neurons and astrocytes Pending AU2022217778A1 (en)

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US202163144743P 2021-02-02 2021-02-02
US63/144,743 2021-02-02
PCT/US2022/014956 WO2022169884A2 (en) 2021-02-02 2022-02-02 Artificial expression constructs for modulating gene expression in gabaergic neurons and astrocytes

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AU2022217778A1 true AU2022217778A1 (en) 2023-08-31
AU2022217778A9 AU2022217778A9 (en) 2023-09-28

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US (1) US20240117377A1 (https=)
EP (1) EP4288064A4 (https=)
JP (1) JP2024505027A (https=)
AU (1) AU2022217778A1 (https=)
CA (1) CA3207224A1 (https=)
WO (1) WO2022169884A2 (https=)

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Publication number Priority date Publication date Assignee Title
WO2025019685A2 (en) * 2023-07-18 2025-01-23 Allen Institute Antisense oligonucleotides and artificial expression constructs for expressing rna in inhibitory neurons
AU2024346721A1 (en) * 2023-09-18 2026-04-09 Allen Institute Artificial expression constructs for modulating gene expression in neurons and astrocytes for the assessment and/or treatment of slc6a1-related disorders

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JP4955540B2 (ja) * 2004-06-04 2012-06-20 フラクスオーム サイエンセズ エイ／エス 多価不飽和脂肪酸生産のための代謝改変細胞
EP1859060A2 (en) * 2005-02-28 2007-11-28 Integragen Human autism susceptibility genes encoding a neurotransmitter transporter and uses thereof
EP3260540A1 (en) * 2010-11-12 2017-12-27 The General Hospital Corporation Polycomb-associated non-coding rnas
WO2013155222A2 (en) * 2012-04-10 2013-10-17 The Regents Of The University Of California Brain-specific enhancers for cell-based therapy
PE20170261A1 (es) * 2014-05-13 2017-04-12 Univ Pennsylvania Composiciones que comprenden virus adenoasociado (aav) que expresa constructos de anticuerpos duales y sus usos
CN110546257B (zh) * 2017-03-17 2024-03-01 阿德夫拉姆生物技术股份有限公司 用于增强基因表达的组合物和方法
AU2019253700B2 (en) * 2018-04-09 2025-08-14 Allen Institute Rescuing voltage-gated sodium channel function in inhibitory neurons
JP7695192B2 (ja) * 2018-10-08 2025-06-18 アレン インスティテュート 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物
CA3173609A1 (en) * 2020-03-27 2021-09-30 Allen Institute Artificial expression constructs for selectively modulating gene expression in non-neuronal brain cells

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EP4288064A2 (en) 2023-12-13
WO2022169884A3 (en) 2022-09-15
JP2024505027A (ja) 2024-02-02
CA3207224A1 (en) 2022-08-11
US20240117377A1 (en) 2024-04-11
EP4288064A4 (en) 2025-01-15
WO2022169884A2 (en) 2022-08-11
AU2022217778A9 (en) 2023-09-28

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