JP2026021360A5 - - Google Patents
Info
- Publication number
- JP2026021360A5 JP2026021360A5 JP2025175276A JP2025175276A JP2026021360A5 JP 2026021360 A5 JP2026021360 A5 JP 2026021360A5 JP 2025175276 A JP2025175276 A JP 2025175276A JP 2025175276 A JP2025175276 A JP 2025175276A JP 2026021360 A5 JP2026021360 A5 JP 2026021360A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- sequence shown
- nucleic acid
- neurons
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862755988P | 2018-11-05 | 2018-11-05 | |
| US62/755,988 | 2018-11-05 | ||
| US201962806684P | 2019-02-15 | 2019-02-15 | |
| US201962806600P | 2019-02-15 | 2019-02-15 | |
| US62/806,600 | 2019-02-15 | ||
| US62/806,684 | 2019-02-15 | ||
| US201962872021P | 2019-07-09 | 2019-07-09 | |
| US62/872,021 | 2019-07-09 | ||
| JP2021523074A JP7590962B2 (ja) | 2018-11-05 | 2019-11-05 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| PCT/US2019/059927 WO2020097121A1 (en) | 2018-11-05 | 2019-11-05 | Artificial expression constructs for selectively modulating gene expression in excitatory cortical neurons |
| JP2024198841A JP7774695B2 (ja) | 2018-11-05 | 2024-11-14 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024198841A Division JP7774695B2 (ja) | 2018-11-05 | 2024-11-14 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2026021360A JP2026021360A (ja) | 2026-02-10 |
| JP2026021360A5 true JP2026021360A5 (https=) | 2026-04-02 |
Family
ID=70612483
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021523074A Active JP7590962B2 (ja) | 2018-11-05 | 2019-11-05 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| JP2024198841A Active JP7774695B2 (ja) | 2018-11-05 | 2024-11-14 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| JP2025175276A Pending JP2026021360A (ja) | 2018-11-05 | 2025-10-17 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021523074A Active JP7590962B2 (ja) | 2018-11-05 | 2019-11-05 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| JP2024198841A Active JP7774695B2 (ja) | 2018-11-05 | 2024-11-14 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20210395780A1 (https=) |
| EP (1) | EP3877529A4 (https=) |
| JP (3) | JP7590962B2 (https=) |
| AU (2) | AU2019375975B2 (https=) |
| CA (1) | CA3118689A1 (https=) |
| WO (1) | WO2020097121A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220249703A1 (en) * | 2019-02-15 | 2022-08-11 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations |
| JP7624728B2 (ja) | 2019-02-25 | 2025-01-31 | ユニバーシティ オブ マサチューセッツ | Ｄｎａ結合ドメイントランスアクチベーター及びその使用 |
| JP7767324B2 (ja) * | 2020-06-04 | 2025-11-11 | アレン インスティテュート | 抑制性新皮質ニューロンにおいて遺伝子発現を選択的に調節する人工発現構築物 |
| WO2022020706A1 (en) * | 2020-07-24 | 2022-01-27 | University Of Massachusetts | Dna-binding domain transactivators and uses thereof |
| WO2022036255A1 (en) * | 2020-08-14 | 2022-02-17 | Allen Institute | Artificial expression constructs for modulating gene expression in striatal neurons |
| GB202013940D0 (en) | 2020-09-04 | 2020-10-21 | Synpromics Ltd | Regulatory nucleic acid sequences |
| WO2022103859A1 (en) * | 2020-11-10 | 2022-05-19 | Allen Institute | Artificial expression constructs for modulating gene expression in chandelier cells |
| EP4277524A4 (en) * | 2021-01-13 | 2025-06-04 | Duke University | Compositions for and methods of improving fluid flux in the brain |
| WO2022212585A1 (en) * | 2021-03-30 | 2022-10-06 | Allen Institute | Artificial expression constructs for modulating gene expression in claustrum neurons |
| WO2022246276A2 (en) * | 2021-05-21 | 2022-11-24 | Allen Institute | Artificial expression constructs for modulating gene expression in neurons within the thalamus |
| CN113736734B (zh) * | 2021-09-23 | 2022-10-25 | 中山大学中山眼科中心 | 一种用于灵长类动物神经元分离的试剂盒及方法 |
| WO2023108021A1 (en) * | 2021-12-07 | 2023-06-15 | Allen Institute | Artificial expression constructs for modulating gene expression in neocortical layer 4 or layer 5 intratelencephalic neurons |
| CA3244907A1 (en) * | 2022-02-24 | 2023-08-31 | Allen Institute | ARTIFICIAL EXPRESSION CONSTRUCTIONS TO MODULATE GENE EXPRESSION IN DOPAMINERGIC NEURONS |
| CN114752624B (zh) * | 2022-04-08 | 2025-04-15 | 中国海洋大学 | 一种侏儒蛤卵子的电穿孔方法 |
| WO2024011224A2 (en) * | 2022-07-08 | 2024-01-11 | The Trustees Of Columbia University In The City Of New York | Regulatory element for cell type specific expression of genes in spinal motor neurons |
| WO2024238448A2 (en) * | 2023-05-12 | 2024-11-21 | Temple University - Of The Commonwealth System Of Higher Education | Chimeric capsid recombinant adeno-associated virus with bbb penetration and microglia targeting (aav-bm) |
| CN117346715B (zh) * | 2023-12-04 | 2024-03-08 | 成都深瑞同华科技有限公司 | 一种配电网架空线路弧垂测定方法、系统及存储介质 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2028268A1 (en) * | 2007-08-20 | 2009-02-25 | Université Libre De Bruxelles | Generation of neuronal cells from pluripotent stem cells |
| WO2014080381A1 (en) * | 2012-11-26 | 2014-05-30 | Ecole Polytechnique Federale De Lausanne (Epfl) | Colorectal cancer classification with differential prognosis and personalized therapeutic responses |
| CL2014003590A1 (es) * | 2014-12-30 | 2015-07-10 | Univ Chile | Virus aav/xbp1s-ha, método de tratamiento genético y su uso en la optimizacion y mejoramiento de las capacidades cognitivas, de memoria y de aprendizaje. |
| MX2019011772A (es) * | 2017-04-03 | 2020-01-09 | Encoded Therapeutics Inc | Expresion transgenica selectiva de tejidos. |
-
2019
- 2019-11-05 WO PCT/US2019/059927 patent/WO2020097121A1/en not_active Ceased
- 2019-11-05 JP JP2021523074A patent/JP7590962B2/ja active Active
- 2019-11-05 EP EP19881101.0A patent/EP3877529A4/en active Pending
- 2019-11-05 US US17/291,584 patent/US20210395780A1/en active Pending
- 2019-11-05 AU AU2019375975A patent/AU2019375975B2/en active Active
- 2019-11-05 CA CA3118689A patent/CA3118689A1/en active Pending
-
2024
- 2024-11-14 JP JP2024198841A patent/JP7774695B2/ja active Active
- 2024-12-31 US US19/007,263 patent/US20250236886A1/en active Pending
-
2025
- 2025-10-02 AU AU2025242185A patent/AU2025242185A1/en active Pending
- 2025-10-17 JP JP2025175276A patent/JP2026021360A/ja active Pending
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