JP2024537165A5 - - Google Patents
Info
- Publication number
- JP2024537165A5 JP2024537165A5 JP2024520839A JP2024520839A JP2024537165A5 JP 2024537165 A5 JP2024537165 A5 JP 2024537165A5 JP 2024520839 A JP2024520839 A JP 2024520839A JP 2024520839 A JP2024520839 A JP 2024520839A JP 2024537165 A5 JP2024537165 A5 JP 2024537165A5
- Authority
- JP
- Japan
- Prior art keywords
- ehgt
- seq
- sequence
- mgt
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163252520P | 2021-10-05 | 2021-10-05 | |
| US63/252,520 | 2021-10-05 | ||
| PCT/US2022/077586 WO2023060112A1 (en) | 2021-10-05 | 2022-10-05 | Artificial expression constructs for modulating gene expression in the cerebellum and a secondary cell type |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024537165A JP2024537165A (ja) | 2024-10-10 |
| JP2024537165A5 true JP2024537165A5 (https=) | 2025-10-01 |
Family
ID=85803726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024520839A Pending JP2024537165A (ja) | 2021-10-05 | 2022-10-05 | 小脳と第2の種類の細胞において遺伝子発現を調節するための人工発現コンストラクト |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250235550A1 (https=) |
| EP (1) | EP4413142A4 (https=) |
| JP (1) | JP2024537165A (https=) |
| AU (1) | AU2022360979A1 (https=) |
| CA (1) | CA3233342A1 (https=) |
| WO (1) | WO2023060112A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2024308266A1 (en) * | 2023-06-28 | 2025-12-18 | Allen Institute | Artificial expression constructs for modulating gene expression in cardiomyocytes |
| WO2025179180A1 (en) * | 2024-02-23 | 2025-08-28 | Allen Institute | Artificial expression constructs for modulating gene expression in motor neurons and cerebellar neurons |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013155222A2 (en) * | 2012-04-10 | 2013-10-17 | The Regents Of The University Of California | Brain-specific enhancers for cell-based therapy |
| US20220249703A1 (en) * | 2019-02-15 | 2022-08-11 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations |
| CA3173609A1 (en) * | 2020-03-27 | 2021-09-30 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in non-neuronal brain cells |
| AU2021261359A1 (en) * | 2020-04-21 | 2022-12-08 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in neocortical layer 5 glutamatergic neurons |
| WO2022246276A2 (en) * | 2021-05-21 | 2022-11-24 | Allen Institute | Artificial expression constructs for modulating gene expression in neurons within the thalamus |
-
2022
- 2022-10-05 EP EP22879443.4A patent/EP4413142A4/en active Pending
- 2022-10-05 JP JP2024520839A patent/JP2024537165A/ja active Pending
- 2022-10-05 WO PCT/US2022/077586 patent/WO2023060112A1/en not_active Ceased
- 2022-10-05 CA CA3233342A patent/CA3233342A1/en active Pending
- 2022-10-05 AU AU2022360979A patent/AU2022360979A1/en active Pending
- 2022-10-05 US US18/698,499 patent/US20250235550A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11932668B2 (en) | Selective recovery | |
| US11091777B2 (en) | Synthetic combinatorial AAV capsid library for targeted gene therapy | |
| El-Shamayleh et al. | Strategies for targeting primate neural circuits with viral vectors | |
| JP2020537543A5 (https=) | ||
| JP2020537542A5 (https=) | ||
| JP2020537544A5 (https=) | ||
| AU2019414426B2 (en) | Methods and materials for single cell transcriptome-based development of AAV vectors and promoters | |
| Taschenberger et al. | A microRNA124 target sequence restores astrocyte specificity of gfaABC1D-driven transgene expression in AAV-mediated gene transfer | |
| JP2022535749A5 (https=) | ||
| CA3063464A1 (en) | High activity regulatory elements | |
| JP2024537165A5 (https=) | ||
| AU2024271436A1 (en) | Engineered blood brain barrier penetrant aav capsids | |
| Kügler | Tissue-specific promoters in the CNS | |
| CA3129757A1 (en) | Dna-binding domain transactivators and uses thereof | |
| US20230279405A1 (en) | Dna-binding domain transactivators and uses thereof | |
| CN116463380A (zh) | 一种重组腺相关病毒载体组合物、外源基因表达系统及方法 | |
| Chen et al. | Vector tropism | |
| US12551574B2 (en) | Recombinant nucleic acids containing alphaherpesvirus promoter sequences | |
| US20250025575A1 (en) | Compositions and Methods for Cell-Specific Expression of Target Genes | |
| US12480098B1 (en) | Adeno-associated virus variant | |
| KR102874560B1 (ko) | 아데노연관바이러스 변이체 | |
| US20250250566A1 (en) | Gene silencing by recombinant aav-amirna in alexander disease | |
| Konkalmatt et al. | Chimeric and Rationally Designed Compact Promoters for Cardiomyocyte-Specific Gene Expression | |
| KR20260057323A (ko) | 아데노연관바이러스 변이체 | |
| CN120981475A (zh) | 变体aav9衣壳蛋白及其用途 |