JP2024503698A5 - - Google Patents

Info

Publication number
JP2024503698A5
JP2024503698A5 JP2023543034A JP2023543034A JP2024503698A5 JP 2024503698 A5 JP2024503698 A5 JP 2024503698A5 JP 2023543034 A JP2023543034 A JP 2023543034A JP 2023543034 A JP2023543034 A JP 2023543034A JP 2024503698 A5 JP2024503698 A5 JP 2024503698A5
Authority
JP
Japan
Prior art keywords
rbm
fusion protein
vaccine according
cov
sars
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023543034A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024503698A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/012607 external-priority patent/WO2022155524A1/en
Publication of JP2024503698A publication Critical patent/JP2024503698A/ja
Publication of JP2024503698A5 publication Critical patent/JP2024503698A5/ja
Pending legal-status Critical Current

Links

JP2023543034A 2021-01-15 2022-01-14 変異型株ベースのコロナウイルスワクチン Pending JP2024503698A (ja)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US202163138228P 2021-01-15 2021-01-15
US63/138,228 2021-01-15
US202163140921P 2021-01-24 2021-01-24
US63/140,921 2021-01-24
US202163161439P 2021-03-15 2021-03-15
US63/161,439 2021-03-15
US202163173972P 2021-04-12 2021-04-12
US63/173,972 2021-04-12
US202163193558P 2021-05-26 2021-05-26
US63/193,558 2021-05-26
US202163222930P 2021-07-16 2021-07-16
US63/222,930 2021-07-16
US202163241944P 2021-09-08 2021-09-08
US63/241,944 2021-09-08
US202163283795P 2021-11-29 2021-11-29
US63/283,795 2021-11-29
US202163284565P 2021-11-30 2021-11-30
US63/284,565 2021-11-30
PCT/US2022/012607 WO2022155524A1 (en) 2021-01-15 2022-01-14 Variant strain-based coronavirus vaccines

Publications (2)

Publication Number Publication Date
JP2024503698A JP2024503698A (ja) 2024-01-26
JP2024503698A5 true JP2024503698A5 (enExample) 2025-04-14

Family

ID=80222159

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023543034A Pending JP2024503698A (ja) 2021-01-15 2022-01-14 変異型株ベースのコロナウイルスワクチン

Country Status (6)

Country Link
US (1) US20240100151A1 (enExample)
EP (1) EP4277655A1 (enExample)
JP (1) JP2024503698A (enExample)
AU (1) AU2022208057A1 (enExample)
CA (1) CA3208486A1 (enExample)
WO (1) WO2022155524A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3134131T3 (en) 2014-04-23 2022-02-07 Modernatx Inc Nucleic acid vaccines
WO2017020026A1 (en) 2015-07-30 2017-02-02 Modernatx, Inc. Concatemeric peptide epitopes rnas
US11564893B2 (en) 2015-08-17 2023-01-31 Modernatx, Inc. Methods for preparing particles and related compositions
MD3718565T2 (ro) 2015-10-22 2022-09-30 Modernatx Inc Vaccinuri împotriva virusului respirator
CN108430456B (zh) 2015-10-22 2022-01-18 摩登纳特斯有限公司 癌症疫苗
US12128113B2 (en) 2016-05-18 2024-10-29 Modernatx, Inc. Polynucleotides encoding JAGGED1 for the treatment of Alagille syndrome
JP6983455B2 (ja) 2016-09-14 2021-12-17 モデルナティーエックス, インコーポレイテッド 高純度rna組成物及びその調製のための方法
CN110167587A (zh) 2016-11-11 2019-08-23 摩登纳特斯有限公司 流感疫苗
US11752206B2 (en) 2017-03-15 2023-09-12 Modernatx, Inc. Herpes simplex virus vaccine
WO2018170270A1 (en) 2017-03-15 2018-09-20 Modernatx, Inc. Varicella zoster virus (vzv) vaccine
WO2018170245A1 (en) 2017-03-15 2018-09-20 Modernatx, Inc. Broad spectrum influenza virus vaccine
WO2018187590A1 (en) 2017-04-05 2018-10-11 Modernatx, Inc. Reduction or elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins
WO2018232357A1 (en) 2017-06-15 2018-12-20 Modernatx, Inc. Rna formulations
CN111212905A (zh) 2017-08-18 2020-05-29 摩登纳特斯有限公司 Rna聚合酶变体
WO2019036683A1 (en) 2017-08-18 2019-02-21 Modernatx, Inc. ANALYTICAL METHODS BY HPLC
WO2019046809A1 (en) 2017-08-31 2019-03-07 Modernatx, Inc. METHODS OF MANUFACTURING LIPID NANOPARTICLES
WO2019148101A1 (en) 2018-01-29 2019-08-01 Modernatx, Inc. Rsv rna vaccines
AU2019345067A1 (en) 2018-09-19 2021-04-08 Modernatx, Inc. High-purity peg lipids and uses thereof
US12151029B2 (en) 2018-09-19 2024-11-26 Modernatx, Inc. PEG lipids and uses thereof
WO2020061457A1 (en) 2018-09-20 2020-03-26 Modernatx, Inc. Preparation of lipid nanoparticles and methods of administration thereof
JP2022521094A (ja) 2019-02-20 2022-04-05 モデルナティエックス インコーポレイテッド 共転写キャッピング用rnaポリメラーゼバリアント
CN113874502A (zh) 2019-03-11 2021-12-31 摩登纳特斯有限公司 补料分批体外转录方法
WO2020190750A1 (en) 2019-03-15 2020-09-24 Modernatx, Inc. Hiv rna vaccines
US12194089B2 (en) 2020-02-04 2025-01-14 CureVac SE Coronavirus vaccine
JP2023525936A (ja) * 2020-05-18 2023-06-19 康希諾(上海)生物科技有限公司 mRNA又はmRNA組成物、その調製方法及び使用
US20240156946A1 (en) 2020-12-22 2024-05-16 CureVac SE Rna vaccine against sars-cov-2 variants
WO2022150717A1 (en) 2021-01-11 2022-07-14 Modernatx, Inc. Seasonal rna influenza virus vaccines
US20220363937A1 (en) 2021-05-14 2022-11-17 Armstrong World Industries, Inc. Stabilization of antimicrobial coatings
US20240382581A1 (en) * 2021-07-09 2024-11-21 Modernatx, Inc. Pan-human coronavirus vaccines
US12397051B2 (en) * 2021-09-14 2025-08-26 Globe Biotech Limited Vaccine for use against coronavirus and variants thereof
WO2023092069A1 (en) * 2021-11-18 2023-05-25 Modernatx, Inc. Sars-cov-2 mrna domain vaccines and methods of use
US12186387B2 (en) 2021-11-29 2025-01-07 BioNTech SE Coronavirus vaccine
US12529047B1 (en) 2021-12-21 2026-01-20 Modernatx, Inc. mRNA quantification methods
EP4577236A1 (en) * 2022-08-22 2025-07-02 The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. Vaccines against coronaviruses
EP4608442A1 (en) 2022-10-28 2025-09-03 GlaxoSmithKline Biologicals S.A. Nucleic acid based vaccine
WO2025166202A1 (en) 2024-01-31 2025-08-07 Modernatx, Inc. Lipid nanoparticle compositions comprising sialic acid derivatives and the uses thereof

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1903054A3 (de) 2001-06-05 2008-07-23 CureVac GmbH Stabilisierte mRNA mit erhöhtem G/C-Gehalt und optimierter Codon Usage für die Gentherapie
JP4691495B2 (ja) * 2004-07-15 2011-06-01 一般財団法人化学及血清療法研究所 コロナウイルススパイクs1融合蛋白及びその発現ベクター
US9012219B2 (en) 2005-08-23 2015-04-21 The Trustees Of The University Of Pennsylvania RNA preparations comprising purified modified RNA for reprogramming cells
DE102005046490A1 (de) 2005-09-28 2007-03-29 Johannes-Gutenberg-Universität Mainz Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
WO2009003222A1 (en) 2007-06-29 2009-01-08 Commonwealth Scientific And Industrial Research Organisation Methods for degrading toxic compounds
EP3156414B1 (en) 2007-09-26 2019-12-04 Intrexon Corporation Synthetic 5'utrs, expression vectors, and methods for increasing transgene expression
CN103911378A (zh) 2007-12-11 2014-07-09 斯克利普斯研究所 涉及mRNA翻译增强因子的组合物和方法
PT2717893T (pt) 2011-06-08 2019-08-20 Translate Bio Inc Composições de nanopartículas lipídicas e métodos para transferência de arnm
WO2013185069A1 (en) 2012-06-08 2013-12-12 Shire Human Genetic Therapies, Inc. Pulmonary delivery of mrna to non-lung target cells
EP2971033B8 (en) 2013-03-15 2019-07-10 ModernaTX, Inc. Manufacturing methods for production of rna transcripts
EP4614148A3 (en) 2013-03-15 2025-12-17 Translate Bio, Inc. Synergistic enhancement of the delivery of nucleic acids via blended formulations
AU2014310933B2 (en) 2013-08-21 2020-05-14 CureVac SE Method for increasing expression of RNA-encoded proteins
ES2806575T3 (es) 2013-11-01 2021-02-18 Curevac Ag ARN modificado con propiedades inmunoestimuladoras disminuidas
WO2015101415A1 (en) 2013-12-30 2015-07-09 Curevac Gmbh Artificial nucleic acid molecules
CN111304231A (zh) 2013-12-30 2020-06-19 库瑞瓦格股份公司 人工核酸分子
DK3134131T3 (en) * 2014-04-23 2022-02-07 Modernatx Inc Nucleic acid vaccines
AU2016342048B2 (en) * 2015-10-22 2022-09-08 Modernatx, Inc. Broad spectrum influenza virus vaccine
MD3718565T2 (ro) * 2015-10-22 2022-09-30 Modernatx Inc Vaccinuri împotriva virusului respirator
EP3405579A1 (en) 2016-01-22 2018-11-28 Modernatx, Inc. Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
JP6983455B2 (ja) 2016-09-14 2021-12-17 モデルナティーエックス, インコーポレイテッド 高純度rna組成物及びその調製のための方法
CN111212905A (zh) 2017-08-18 2020-05-29 摩登纳特斯有限公司 Rna聚合酶变体
JP2023511633A (ja) * 2020-01-28 2023-03-20 モデルナティエックス インコーポレイテッド コロナウイルスrnaワクチン
EP3886897A1 (en) * 2020-02-04 2021-10-06 CureVac AG Coronavirus vaccine
AU2021215938A1 (en) * 2020-02-07 2022-09-01 Modernatx, Inc. Sars-cov-2 mrna domain vaccines
WO2021213945A1 (en) * 2020-04-22 2021-10-28 Pfizer Inc. Coronavirus vaccine
WO2021226436A1 (en) * 2020-05-07 2021-11-11 Translate Bio, Inc. Optimized nucleotide sequences encoding sars-cov-2 antigens

Similar Documents

Publication Publication Date Title
JP2024503699A5 (enExample)
JP2023513073A5 (enExample)
JP2024513999A5 (enExample)
JP2024514182A5 (enExample)
ES3058501T3 (en) Rsv f protein mutants
ES2869199T3 (es) Sistemas de expresión
JP2022136230A5 (enExample)
TW202140518A (zh) 冠狀病毒疫苗
IL278418B2 (en) Vaccine composition
JP2024542188A5 (enExample)
JP2024156964A5 (enExample)
TW201202262A (en) Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups
JP2023546369A5 (enExample)
Ibañez et al. M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A
JP2022533318A (ja) 気道感染の治療または予防のためのサブユニットワクチン
BR112012024872B1 (pt) Composições farmacêuticas compreendendo um polipeptídeo contendo pelo menos um motivo cxxc e antígenos heterólogos e seus usos
JP2017538672A (ja) Cmv由来改変ウイルス様粒子
JP2013523887A5 (enExample)
JP2024542635A5 (enExample)
JP2010536878A (ja) インフルエンザタンパク質を製造および使用する組成物および方法
JP2019088329A5 (enExample)
JP2024539512A5 (enExample)
JP2021511077A (ja) インフルエンザウイルスワクチン及びその使用
JP2020519663A (ja) Rsv感染に対する防御免疫を誘導するための方法及び組成物
JP2023532290A5 (enExample)