|
USRE28819E
(en)
|
1972-12-08 |
1976-05-18 |
Syntex (U.S.A.) Inc. |
Dialkylated glycol compositions and medicament preparations containing same
|
|
US4255329A
(en)
|
1973-10-02 |
1981-03-10 |
Syva Company |
Double receptor fluorescent immunoassay
|
|
US4117149A
(en)
|
1975-09-12 |
1978-09-26 |
Pfizer Inc. |
4-oxo-4h-benzopyrans as animal growth promotants
|
|
US4171365A
(en)
|
1977-08-05 |
1979-10-16 |
Sterling Drug Inc. |
Antiviral aryloxyalkylpyrazoles
|
|
US4261928A
(en)
|
1977-08-05 |
1981-04-14 |
Sterling Drug Inc. |
2-Benzoyl-8-(2-chloro-4-methoxyphenoxy)-1-phenyl-1-octanone
|
|
US4234725A
(en)
|
1979-10-24 |
1980-11-18 |
Sterling Drug Inc. |
4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-[4-(4-morpholinyl)-1-oxobutyl]-1H-pyrazole
|
|
US4232161A
(en)
|
1979-10-24 |
1980-11-04 |
Sterling Drug Inc. |
4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-(2-pyridinyl)-1H-pyrazole
|
|
US4410545A
(en)
|
1981-02-13 |
1983-10-18 |
Syntex (U.S.A.) Inc. |
Carbonate diester solutions of PGE-type compounds
|
|
US4328245A
(en)
|
1981-02-13 |
1982-05-04 |
Syntex (U.S.A.) Inc. |
Carbonate diester solutions of PGE-type compounds
|
|
US4358603A
(en)
|
1981-04-16 |
1982-11-09 |
Syntex (U.S.A.) Inc. |
Acetal stabilized prostaglandin compositions
|
|
US4668640A
(en)
|
1981-12-11 |
1987-05-26 |
Abbott Laboratories |
Fluorescence polarization immunoassay utilizing substituted carboxyfluoresceins
|
|
US4409239A
(en)
|
1982-01-21 |
1983-10-11 |
Syntex (U.S.A.) Inc. |
Propylene glycol diester solutions of PGE-type compounds
|
|
GB2120242A
(en)
|
1982-04-30 |
1983-11-30 |
Erba Farmitalia |
Ergoline derivatives
|
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US4764521A
(en)
|
1983-07-18 |
1988-08-16 |
Eli Lilly And Company |
Leukotriene antagonists and a method of use there as
|
|
US5585112A
(en)
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
|
IT1246382B
(it)
|
1990-04-17 |
1994-11-18 |
Eurand Int |
Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
|
|
US5543390A
(en)
|
1990-11-01 |
1996-08-06 |
State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University |
Covalent microparticle-drug conjugates for biological targeting
|
|
US6010715A
(en)
|
1992-04-01 |
2000-01-04 |
Bertek, Inc. |
Transdermal patch incorporating a polymer film incorporated with an active agent
|
|
US6024975A
(en)
|
1992-04-08 |
2000-02-15 |
Americare International Diagnostics, Inc. |
Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
|
|
US5315015A
(en)
|
1992-11-10 |
1994-05-24 |
Hoffmann-La Roche Inc. |
Compounds having improved fluorescence in fluorescence polarization immunoassays and immunoassays utilizing same
|
|
US6274552B1
(en)
|
1993-03-18 |
2001-08-14 |
Cytimmune Sciences, Inc. |
Composition and method for delivery of biologically-active factors
|
|
AU668818B2
(en)
|
1993-04-07 |
1996-05-16 |
Taiho Pharmaceutical Co., Ltd. |
Thiazolidine derivative and pharmaceutical composition containing the same
|
|
US5523092A
(en)
|
1993-04-14 |
1996-06-04 |
Emory University |
Device for local drug delivery and methods for using the same
|
|
US5985307A
(en)
|
1993-04-14 |
1999-11-16 |
Emory University |
Device and method for non-occlusive localized drug delivery
|
|
US6004534A
(en)
|
1993-07-23 |
1999-12-21 |
Massachusetts Institute Of Technology |
Targeted polymerized liposomes for improved drug delivery
|
|
US5744368A
(en)
|
1993-11-04 |
1998-04-28 |
Research Foundation Of State University Of New York |
Methods for the detection of soluble amyloid β-protein (βAP) or soluble transthyretin (TTR)
|
|
US5759542A
(en)
|
1994-08-05 |
1998-06-02 |
New England Deaconess Hospital Corporation |
Compositions and methods for the delivery of drugs by platelets for the treatment of cardiovascular and other diseases
|
|
US5660854A
(en)
|
1994-11-28 |
1997-08-26 |
Haynes; Duncan H |
Drug releasing surgical implant or dressing material
|
|
US5983134A
(en)
|
1995-04-23 |
1999-11-09 |
Electromagnetic Bracing Systems Inc. |
Electrophoretic cuff apparatus drug delivery system
|
|
US6316652B1
(en)
|
1995-06-06 |
2001-11-13 |
Kosta Steliou |
Drug mitochondrial targeting agents
|
|
US6167301A
(en)
|
1995-08-29 |
2000-12-26 |
Flower; Ronald J. |
Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
|
|
US6039975A
(en)
|
1995-10-17 |
2000-03-21 |
Hoffman-La Roche Inc. |
Colon targeted delivery system
|
|
TW345603B
(en)
|
1996-05-29 |
1998-11-21 |
Gmundner Fertigteile Gmbh |
A noise control device for tracks
|
|
US5985317A
(en)
|
1996-09-06 |
1999-11-16 |
Theratech, Inc. |
Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
|
|
JP2000508339A
(ja)
|
1996-10-01 |
2000-07-04 |
シーマ・ラブス・インコーポレイテッド |
味隠蔽マイクロカプセル組成物及び製造方法
|
|
US6131570A
(en)
|
1998-06-30 |
2000-10-17 |
Aradigm Corporation |
Temperature controlling device for aerosol drug delivery
|
|
US5860957A
(en)
|
1997-02-07 |
1999-01-19 |
Sarcos, Inc. |
Multipathway electronically-controlled drug delivery system
|
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
|
US6060082A
(en)
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
|
US5948433A
(en)
|
1997-08-21 |
1999-09-07 |
Bertek, Inc. |
Transdermal patch
|
|
CN1152673C
(zh)
|
1997-10-28 |
2004-06-09 |
坂东化学株式会社 |
皮肤贴附药片及其基片的制造方法
|
|
US6048736A
(en)
|
1998-04-29 |
2000-04-11 |
Kosak; Kenneth M. |
Cyclodextrin polymers for carrying and releasing drugs
|
|
US6271359B1
(en)
|
1999-04-14 |
2001-08-07 |
Musc Foundation For Research Development |
Tissue-specific and pathogen-specific toxic agents and ribozymes
|
|
US6256533B1
(en)
|
1999-06-09 |
2001-07-03 |
The Procter & Gamble Company |
Apparatus and method for using an intracutaneous microneedle array
|
|
EP1248869A2
(en)
*
|
2000-01-07 |
2002-10-16 |
Transform Pharmaceuticals, Inc. |
High-throughput formation, identification, and analysis of diverse solid-forms
|
|
US6261595B1
(en)
|
2000-02-29 |
2001-07-17 |
Zars, Inc. |
Transdermal drug patch with attached pocket for controlled heating device
|
|
JP2005513026A
(ja)
|
2001-11-15 |
2005-05-12 |
インサイト サン ディエゴ インコーポレイテッド |
高コレステロール血症、異脂肪血症および他の代謝障害；癌、および他の疾患を治療するｎ−置換複素環
|
|
WO2003101927A1
(en)
|
2002-05-31 |
2003-12-11 |
Proteotech, Inc. |
Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer's disease, type 2 diabetes, and parkinson's disease
|
|
WO2004096808A1
(en)
|
2003-04-28 |
2004-11-11 |
De Novo Pharmaceuticals Limited |
Triazine compounds and their use
|
|
DE602005025755D1
(de)
|
2004-06-04 |
2011-02-17 |
Teva Pharma |
Irbesartan enthaltende pharmazeutische zusammensetzung
|
|
US8026366B2
(en)
|
2004-06-18 |
2011-09-27 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
|
|
JP2007284350A
(ja)
|
2004-07-27 |
2007-11-01 |
Takeda Chem Ind Ltd |
糖尿病治療剤
|
|
WO2006088694A1
(en)
|
2005-02-14 |
2006-08-24 |
Wyeth |
SUBSTITUTED THIENYL AND FURYL ACYLGUANIDINES AS β-SECRETASE MODULATORS
|
|
EP1919288A4
(en)
|
2005-07-18 |
2009-12-16 |
Horizon Therapeutics Inc |
FAMOTIDINE- AND IBUPROGEN-BASED MEDICAMENTS AND THEIR ADMINISTRATION
|
|
KR101450356B1
(ko)
*
|
2006-11-24 |
2014-10-15 |
에이씨 이뮨 에스.에이. |
알츠하이머와 같은 아밀로이드 또는 아밀로이드-유사 단백질과 관련된 질환의 치료를 위한 ｎ-(메틸)-1ｈ-피라졸-3-아민, ｎ-(메틸)-피리딘-2-아민 및 ｎ-(메틸)-티아졸-2-아민 유도체
|
|
US20130012485A1
(en)
|
2006-12-22 |
2013-01-10 |
Baeschlin Daniel Kaspar |
Organic compounds
|
|
ES2395872T3
(es)
|
2007-05-11 |
2013-02-15 |
Eli Lilly And Company |
2-[4-(Pirazol-4-ilalquil)piperazin-1-il]-3-fenil pirazinas y piridinas y 3-[4-(pirazol-4-ilalquil)piperazin-1-il]-2-fenil piridinas como antagonistas del receptor de 5-HT7
|
|
EP2167464B1
(en)
|
2007-05-25 |
2014-12-03 |
AbbVie Deutschland GmbH & Co KG |
Heterocyclic compounds as positive modulators of metabotropic glutamate receptor 2 (mglu2 receptor)
|
|
HRP20100611T1
(hr)
|
2007-06-06 |
2010-12-31 |
Torrent Pharmaceuticals Ltd |
Novi spojevi
|
|
MX2009013213A
(es)
|
2007-06-08 |
2010-03-30 |
Abbott Lab |
Indazoles 5-sustituidos 5-heteroarilo como inhibidores de cinasa.
|
|
WO2009086303A2
(en)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
GEP20125708B
(en)
|
2008-03-26 |
2012-12-10 |
Novartis Ag |
Hydroxamate-based inhibitors of deacetylases b
|
|
JO3041B1
(ar)
|
2008-07-25 |
2016-09-05 |
Galapagos Nv |
مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
|
|
US8048887B2
(en)
|
2008-09-11 |
2011-11-01 |
Bristol-Myers Squibb Company |
Compounds for the treatment of hepatitis C
|
|
US7994171B2
(en)
|
2008-09-11 |
2011-08-09 |
Bristol-Myers Squibb Company |
Compounds for the treatment of hepatitis C
|
|
MX360460B
(es)
|
2008-10-20 |
2018-11-05 |
Alnylam Pharmaceuticals Inc |
Composiciones y metodos para inhibir la expresion de transtiretina.
|
|
AR074199A1
(es)
|
2008-11-20 |
2010-12-29 |
Glaxosmithkline Llc |
Compuesto de 6-(4-pirimidinil)-1h-indazol, composiciones farmaceuticas que lo comprenden y su uso para preparar un medicamento util para el tratamiento o disminucion de la gravedad del cancer.
|
|
PE20121172A1
(es)
|
2009-10-14 |
2012-09-05 |
Merck Sharp & Dohme |
Piperidinas sustituidas con actividad en la hdm2
|
|
AR079022A1
(es)
|
2009-11-02 |
2011-12-21 |
Sanofi Aventis |
Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion
|
|
HRP20211752T1
(hr)
|
2010-04-07 |
2022-02-18 |
Vertex Pharmaceuticals Incorporated |
Farmaceutski pripravci 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il)ciklopropankarboksamido)-3-metilpiridin-2-il)benzojeve kiseline i njihova primjena
|
|
EP2566333A4
(en)
|
2010-05-07 |
2014-04-02 |
Univ Leland Stanford Junior |
IDENTIFICATION OF STABILIZERS OF MULTIMEDER PROTEINS
|
|
CN103370326B
(zh)
|
2010-12-16 |
2016-05-11 |
阿勒根公司 |
作为趋化因子受体调节剂的磷衍生物
|
|
US9169214B2
(en)
|
2012-12-21 |
2015-10-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compounds and compositions that bind and stabilize transthyretin and their use for inhibiting transthyretin amyloidosis and protein-protein interactions
|
|
WO2016025129A1
(en)
*
|
2014-08-14 |
2016-02-18 |
Alhamadsheh Mamoun M |
Conjugation of pharmaceutically active agents with transthyretin ligands through adjustable linkers to increase serum half-life
|
|
PT4070788T
(pt)
|
2015-06-30 |
2023-06-06 |
Gilead Sciences Inc |
Formulações farmacêuticas
|
|
UA121775C2
(uk)
|
2015-07-31 |
2020-07-27 |
Пфайзер Інк. |
1,1,1-трифтор-3-гідроксипропан-2-ілкарбаматні похідні та 1,1,1-трифтор-4-гідроксибутан-2-ілкарбаматні похідні як інгібітори magl
|
|
TW202332423A
(zh)
|
2016-10-12 |
2023-08-16 |
美商全球血液治療公司 |
包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
|
|
CN116730920A
(zh)
|
2017-02-17 |
2023-09-12 |
文涵治疗有限公司 |
Ag-10的制备方法、其中间体及其盐
|
|
TWI817999B
(zh)
|
2018-03-23 |
2023-10-11 |
美商文涵治療有限公司 |
使用ag10治療ttr澱粉樣沉積症之方法
|
|
SI3836920T1
(sl)
|
2018-08-17 |
2026-02-27 |
Eidos Therapeutics, Inc. |
Formulacije AG10
|