JP2024175018A5 - - Google Patents
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- Publication number
- JP2024175018A5 JP2024175018A5 JP2024158746A JP2024158746A JP2024175018A5 JP 2024175018 A5 JP2024175018 A5 JP 2024175018A5 JP 2024158746 A JP2024158746 A JP 2024158746A JP 2024158746 A JP2024158746 A JP 2024158746A JP 2024175018 A5 JP2024175018 A5 JP 2024175018A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- pharmaceutical combination
- combination according
- alkyl
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862755196P | 2018-11-02 | 2018-11-02 | |
| US62/755,196 | 2018-11-02 | ||
| PCT/US2019/059711 WO2020093061A1 (en) | 2018-11-02 | 2019-11-04 | Therapeutic methods |
| JP2021525039A JP7588855B2 (ja) | 2018-11-02 | 2019-11-04 | 治療方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525039A Division JP7588855B2 (ja) | 2018-11-02 | 2019-11-04 | 治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024175018A JP2024175018A (ja) | 2024-12-17 |
| JP2024175018A5 true JP2024175018A5 (https=) | 2025-04-14 |
Family
ID=70463345
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525039A Active JP7588855B2 (ja) | 2018-11-02 | 2019-11-04 | 治療方法 |
| JP2024158746A Pending JP2024175018A (ja) | 2018-11-02 | 2024-09-13 | 治療方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525039A Active JP7588855B2 (ja) | 2018-11-02 | 2019-11-04 | 治療方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220031847A1 (https=) |
| EP (1) | EP3873530A4 (https=) |
| JP (2) | JP7588855B2 (https=) |
| KR (1) | KR20210120988A (https=) |
| CN (1) | CN113365662A (https=) |
| AU (1) | AU2019370563B2 (https=) |
| BR (1) | BR112021008449A2 (https=) |
| CA (1) | CA3118142A1 (https=) |
| EA (1) | EA202191210A1 (https=) |
| IL (1) | IL282794B2 (https=) |
| MX (1) | MX2021005130A (https=) |
| NZ (1) | NZ776256A (https=) |
| SG (1) | SG11202104461XA (https=) |
| WO (1) | WO2020093061A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3020585A1 (en) * | 2016-04-11 | 2017-10-19 | Arbutus Biopharma Corporation | Targeted nucleic acid conjugate compositions |
| JP2022506517A (ja) * | 2018-11-02 | 2022-01-17 | アルブータス・バイオファーマー・コーポレイション | 標的指向化二価結合体 |
| EP4007811A2 (en) * | 2019-08-01 | 2022-06-08 | Alnylam Pharmaceuticals, Inc. | Carboxypeptidase b2 (cpb2) irna compositions and methods of use thereof |
| AU2020398708A1 (en) * | 2019-12-06 | 2022-07-14 | Genevant Sciences Gmbh | Conjugates and methods for treating liver fibrosis |
| CN114901360A (zh) | 2019-12-20 | 2022-08-12 | 库瑞瓦格股份公司 | 用于递送核酸的新型脂质纳米颗粒 |
| CN114846051A (zh) * | 2019-12-20 | 2022-08-02 | 阿布特斯生物制药公司 | 合成方法和中间体 |
| EP4228658A4 (en) | 2020-10-14 | 2025-02-19 | George Mason Research Foundation, Inc. | IONIZABLE LIPIDS AND METHODS FOR THE PRODUCTION AND USE THEREOF |
| US11649260B2 (en) | 2021-06-18 | 2023-05-16 | Hongene Biotech Corporation | Functionalized N-acetylgalactosamine nucleosides |
| EP4396193A4 (en) | 2021-08-30 | 2025-07-02 | Hongene Biotech Corp | FUNCTIONALIZED N-ACETYLGALACTOSAMINE ANALOGUES |
| US20240398933A1 (en) | 2021-09-03 | 2024-12-05 | CureVac SE | Novel lipid nanoparticles for delivery of nucleic acids comprising phosphatidylserine |
| WO2023097186A1 (en) * | 2021-11-24 | 2023-06-01 | The Regents Of The University Of California | Compositions and methods for enhancing visual function |
| JP2024546585A (ja) | 2021-12-15 | 2024-12-26 | ホンジーン バイオテック コーポレイション | 官能基化ｎ－アセチルガラクトサミンアナログ |
| CN118591552A (zh) * | 2022-01-30 | 2024-09-03 | 成都凌泰氪生物技术有限公司 | 一种配体、其制备方法及应用 |
| AU2023238507A1 (en) * | 2022-03-25 | 2024-10-31 | Hansoh Bio Llc | Bicyclic heterocycles and their ligands for targeted delivery of therapeutic agents |
| US20250215042A1 (en) * | 2022-04-01 | 2025-07-03 | Genevant Sciences Gmbh | Mannose-targeted compositions |
| WO2024057190A2 (en) * | 2022-09-12 | 2024-03-21 | Genevant Sciences Gmbh | Targeted compositions |
| EP4342460A1 (en) | 2022-09-21 | 2024-03-27 | NovoArc GmbH | Lipid nanoparticle with nucleic acid cargo |
| WO2024118503A1 (en) | 2022-11-28 | 2024-06-06 | Hongene Biotech Corporation | Functionalized n-acetylgalactosamine analogs |
| WO2024125597A1 (en) | 2022-12-14 | 2024-06-20 | Providence Therapeutics Holdings Inc. | Compositions and methods for infectious diseases |
| CN116535449B (zh) * | 2023-03-22 | 2025-09-16 | 华东理工大学 | 一种糖基没食子酸类衍生物及其制备方法与在制备乳腺癌靶向诊疗材料中的应用 |
| CN118993970B (zh) * | 2023-05-17 | 2025-12-23 | 苏州富士莱医药股份有限公司 | 一种l96侧链化合物的制备方法 |
| CN119219716A (zh) * | 2023-06-30 | 2024-12-31 | 上海维申医药有限公司 | 新型GalNAc的靶向递送片段及其制备和应用 |
| GB202311334D0 (en) * | 2023-07-24 | 2023-09-06 | Astrazeneca Ab | Multivalent cargo-carrying complexes and uses thereof |
| IL326647A (en) | 2023-09-01 | 2026-04-01 | Novoarc Gmbh | Lipid nanoparticles with a nucleic acid charge and an ionizable lipid |
| CN117624266A (zh) * | 2023-10-19 | 2024-03-01 | 弘亮(上海)生物医药科技有限公司 | 一种肝靶向化合物及其寡核苷酸缀合物、偶联方法与应用 |
| GB202408360D0 (en) | 2024-06-11 | 2024-07-24 | Cancer Research Tech Ltd | Tumour sensitisation |
| CN121045314B (zh) * | 2025-10-31 | 2026-04-14 | 南昌市第一医院 | 一种靶向降解hmgb1的化合物及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2285853B1 (en) * | 2008-05-13 | 2013-02-27 | University of Washington | Micellic assemblies |
| US9415113B2 (en) * | 2009-11-18 | 2016-08-16 | University Of Washington | Targeting monomers and polymers having targeting blocks |
| AU2014296278C1 (en) * | 2013-07-30 | 2023-02-02 | Genevant Sciences Gmbh | Block copolymers and their conjugates or complexes with oligonucleotides |
| JP2018509387A (ja) * | 2015-01-21 | 2018-04-05 | フェーズアールエックス インコーポレイテッド | 細胞に治療および診断剤を送達するための方法、組成物、ならびにシステム |
| CA3020585A1 (en) * | 2016-04-11 | 2017-10-19 | Arbutus Biopharma Corporation | Targeted nucleic acid conjugate compositions |
| EP3562510A4 (en) * | 2016-12-30 | 2021-01-06 | Genevant Sciences GmbH | BRANCHED PEG MOLECULES AND ASSOCIATED COMPOSITIONS AND PROCEDURES |
| MX2019012280A (es) * | 2017-04-11 | 2020-01-23 | Arbutus Biopharma Corp | Composiciones dirigidas. |
-
2019
- 2019-11-04 EP EP19880313.2A patent/EP3873530A4/en active Pending
- 2019-11-04 KR KR1020217016674A patent/KR20210120988A/ko not_active Ceased
- 2019-11-04 CA CA3118142A patent/CA3118142A1/en active Pending
- 2019-11-04 EA EA202191210A patent/EA202191210A1/ru unknown
- 2019-11-04 SG SG11202104461XA patent/SG11202104461XA/en unknown
- 2019-11-04 AU AU2019370563A patent/AU2019370563B2/en active Active
- 2019-11-04 US US17/290,549 patent/US20220031847A1/en active Pending
- 2019-11-04 CN CN201980087524.XA patent/CN113365662A/zh active Pending
- 2019-11-04 IL IL282794A patent/IL282794B2/en unknown
- 2019-11-04 WO PCT/US2019/059711 patent/WO2020093061A1/en not_active Ceased
- 2019-11-04 NZ NZ776256A patent/NZ776256A/en unknown
- 2019-11-04 JP JP2021525039A patent/JP7588855B2/ja active Active
- 2019-11-04 BR BR112021008449-5A patent/BR112021008449A2/pt unknown
- 2019-11-04 MX MX2021005130A patent/MX2021005130A/es unknown
-
2024
- 2024-09-13 JP JP2024158746A patent/JP2024175018A/ja active Pending
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