JP2024037892A5 - - Google Patents
Info
- Publication number
- JP2024037892A5 JP2024037892A5 JP2023210859A JP2023210859A JP2024037892A5 JP 2024037892 A5 JP2024037892 A5 JP 2024037892A5 JP 2023210859 A JP2023210859 A JP 2023210859A JP 2023210859 A JP2023210859 A JP 2023210859A JP 2024037892 A5 JP2024037892 A5 JP 2024037892A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- unsubstituted
- substituted
- hydrogen
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163231590P | 2021-08-10 | 2021-08-10 | |
| US63/231,590 | 2021-08-10 | ||
| JP2023516136A JP7406672B2 (ja) | 2021-08-10 | 2022-08-08 | ニコチンアミド系ｒｉｐｋ１阻害剤 |
| PCT/US2022/039689 WO2023018643A1 (en) | 2021-08-10 | 2022-08-08 | Nicotinamide ripk1 inhibitors |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023516136A Division JP7406672B2 (ja) | 2021-08-10 | 2022-08-08 | ニコチンアミド系ｒｉｐｋ１阻害剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024037892A JP2024037892A (ja) | 2024-03-19 |
| JP2024037892A5 true JP2024037892A5 (https=) | 2025-08-18 |
Family
ID=83439074
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023516136A Active JP7406672B2 (ja) | 2021-08-10 | 2022-08-08 | ニコチンアミド系ｒｉｐｋ１阻害剤 |
| JP2023210859A Pending JP2024037892A (ja) | 2021-08-10 | 2023-12-14 | ニコチンアミド系ｒｉｐｋ１阻害剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023516136A Active JP7406672B2 (ja) | 2021-08-10 | 2022-08-08 | ニコチンアミド系ｒｉｐｋ１阻害剤 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11767310B2 (https=) |
| EP (2) | EP4643949A3 (https=) |
| JP (2) | JP7406672B2 (https=) |
| KR (2) | KR20240135076A (https=) |
| CN (1) | CN117460722A (https=) |
| AR (1) | AR126733A1 (https=) |
| AU (1) | AU2022328136A1 (https=) |
| BR (1) | BR112023025850A2 (https=) |
| CA (1) | CA3219155A1 (https=) |
| CO (1) | CO2023017151A2 (https=) |
| IL (1) | IL308349A (https=) |
| MX (1) | MX2023014817A (https=) |
| TW (1) | TW202321211A (https=) |
| WO (1) | WO2023018643A1 (https=) |
| ZA (1) | ZA202310682B (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117460722A (zh) | 2021-08-10 | 2024-01-26 | 艾伯维公司 | 烟酰胺ripk1抑制剂 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9606546A (pt) | 1995-08-02 | 1998-07-14 | Uriach & Cia Sa J | Novas carboxamidas com atividade fungicida |
| US6218387B1 (en) | 1996-12-20 | 2001-04-17 | Hoechst Aktiengesellschaft | Vitronectin receptor anatagonists, their preparation and their use |
| US6723727B1 (en) | 1996-12-20 | 2004-04-20 | Hoechst Aktiengesellschaft | Substituted purine derivatives, processes for their preparation, their use, and compositions comprising them |
| EP1664026B1 (en) | 2003-08-15 | 2009-01-21 | Merck & Co., Inc. | Mitotic kinesin inhibitors |
| JP2007502773A (ja) | 2003-08-15 | 2007-02-15 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂キネシン阻害薬 |
| US7112316B1 (en) | 2005-08-08 | 2006-09-26 | Uop Llc | Process for preparing molecular sieves via continuous addition of nutrients |
| EP1984355A2 (en) | 2006-02-16 | 2008-10-29 | Takeda Pharmaceutical Company Limited | Cyclic amine compound and use thereof for the prophylaxis or treatment of hypertension |
| AU2008302746B2 (en) | 2007-09-20 | 2014-07-03 | Amgen Inc. | 1-(4-(benzylbenzamid0) -benzyl) azetidine-3-carboxylic acid derivatives and related compounds as SlP receptor modulators for the treatment of immune disorders |
| ES2524883T3 (es) | 2008-03-18 | 2014-12-15 | Merck Sharp & Dohme Corp. | 4-Hidroxipirimidina-5-carboxamidas sustituidas |
| US9278922B2 (en) | 2009-04-15 | 2016-03-08 | Abbvie Inc. | Anti-viral compounds |
| US8653172B2 (en) | 2010-03-17 | 2014-02-18 | Exxonmobil Chemical Patents Inc. | Plasticiser blends and compositions and articles made therefrom |
| JP5947307B2 (ja) | 2010-10-20 | 2016-07-06 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | Ｋｃｎｑ２／３調節因子としての置換６−アミノ−ニコチンアミド |
| WO2013049255A1 (en) | 2011-09-26 | 2013-04-04 | Vanderbilt University | Substitued 5-(prop-1-yn-1-yl)picolinamide analogs as allosteric modulators of mglur5 receptors |
| TWI637951B (zh) | 2013-02-15 | 2018-10-11 | 英商葛蘭素史克智慧財產發展有限公司 | 作為激酶抑制劑之雜環醯胺類 |
| GEAP201814220A (en) | 2013-12-24 | 2018-03-12 | Oncotartis Inc | Benzamide and nicotinamide compounds and methods of using same |
| KR101555033B1 (ko) | 2014-07-28 | 2015-09-23 | 충남대학교산학협력단 | 신규한 메타논 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 망막 질환의 예방 또는 치료용 약학적 조성물 |
| KR101551313B1 (ko) | 2014-07-28 | 2015-09-09 | 충남대학교산학협력단 | 신규한 인덴 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 망막 질환의 예방 또는 치료용 약학적 조성물 |
| CN106573006A (zh) | 2014-08-21 | 2017-04-19 | 葛兰素史密斯克莱知识产权发展有限公司 | 作为药物的rip1激酶抑制剂杂环酰胺 |
| WO2016101885A1 (en) | 2014-12-24 | 2016-06-30 | National Institute Of Biological Sciences, Beijing | Necrosis inhibitors |
| TWI730959B (zh) | 2015-05-19 | 2021-06-21 | 英商葛蘭素史克智慧財產發展有限公司 | 作為激酶抑制劑之雜環醯胺 |
| EP3317269B1 (en) | 2015-07-02 | 2022-09-21 | F. Hoffmann-La Roche AG | Bicyclic lactams as receptor-interacting protein-1 (rip1) kinase inhibitors for treating e.g. inflammatory diseases |
| AU2016340527B2 (en) | 2015-10-23 | 2020-09-17 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| WO2017096301A1 (en) | 2015-12-04 | 2017-06-08 | Denali Therapeutics Inc. | Isoxazolidine derived inhibitors of receptor interacting protein kinase 1 (ripk 1) |
| US10961258B2 (en) | 2015-12-21 | 2021-03-30 | Glaxosmithkline Intellectual Property Development Limited | Heterocyclic amides as kinase inhibitors |
| IL287136B2 (en) | 2016-02-05 | 2023-09-01 | Denali Therapeutics Inc | Receptor inhibitors - interacting with protein kinase 1 |
| JP7121731B2 (ja) | 2016-09-26 | 2022-08-18 | タフツ・ユニバーシティ | ウリジンヌクレオシド誘導体、組成物及び使用方法 |
| EP3580220B1 (en) | 2017-02-13 | 2021-11-17 | Bristol-Myers Squibb Company | Aminotriazolopyridines as kinase inhibitors |
| DE102017211104B3 (de) | 2017-06-29 | 2018-10-18 | Bundesdruckerei Gmbh | Verfahren und Vorrichtung zum Verifizieren eines elektrolumineszierenden Sicherheitsmerkmals in einem Wert- oder Sicherheitsdokument unter Ausnutzung von zusätzlicher Lichtstrahlung |
| HRP20231381T1 (hr) | 2018-05-03 | 2024-03-01 | Rigel Pharmaceuticals, Inc. | Spojevi inhibitori rip1 i postupci za njihovo dobivanje i upotrebu |
| JP7162372B2 (ja) * | 2018-07-02 | 2022-10-28 | 深▲チェン▼市塔吉瑞生物医薬有限公司 | キナーゼ活性を阻害するためのアルキニル（ヘテロ）芳香族化合物 |
| WO2020013531A1 (ko) | 2018-07-10 | 2020-01-16 | 보로노이바이오 주식회사 | N-(3-(이미다조[1,2-b]피리다진-3-일에티닐)-4-메틸페닐)-5-페닐-4,5-다이하이드로-1H-피라졸-1-카복사마이드 유도체 및 이를 유효성분으로 포함하는 키나아제 관련 질환 치료용 약학적 조성물 |
| WO2020149553A1 (ko) * | 2019-01-15 | 2020-07-23 | 주식회사 보로노이 | 아릴 또는 헤테로아릴 유도체, 및 이를 유효성분으로 포함하는 키나아제 관련 질환 치료용 약학적 조성물 |
| CN117460722A (zh) | 2021-08-10 | 2024-01-26 | 艾伯维公司 | 烟酰胺ripk1抑制剂 |
-
2022
- 2022-08-08 CN CN202280041334.6A patent/CN117460722A/zh active Pending
- 2022-08-08 WO PCT/US2022/039689 patent/WO2023018643A1/en not_active Ceased
- 2022-08-08 BR BR112023025850A patent/BR112023025850A2/pt unknown
- 2022-08-08 IL IL308349A patent/IL308349A/en unknown
- 2022-08-08 EP EP25189687.4A patent/EP4643949A3/en active Pending
- 2022-08-08 MX MX2023014817A patent/MX2023014817A/es unknown
- 2022-08-08 CA CA3219155A patent/CA3219155A1/en active Pending
- 2022-08-08 JP JP2023516136A patent/JP7406672B2/ja active Active
- 2022-08-08 AR ARP220102125A patent/AR126733A1/es not_active Application Discontinuation
- 2022-08-08 TW TW111129732A patent/TW202321211A/zh unknown
- 2022-08-08 AU AU2022328136A patent/AU2022328136A1/en active Pending
- 2022-08-08 KR KR1020247029687A patent/KR20240135076A/ko active Pending
- 2022-08-08 EP EP22777032.8A patent/EP4301744A1/en not_active Withdrawn
- 2022-08-08 US US17/882,709 patent/US11767310B2/en active Active
- 2022-08-08 KR KR1020237038931A patent/KR102707109B1/ko active Active
-
2023
- 2023-11-17 ZA ZA2023/10682A patent/ZA202310682B/en unknown
- 2023-12-11 CO CONC2023/0017151A patent/CO2023017151A2/es unknown
- 2023-12-14 JP JP2023210859A patent/JP2024037892A/ja active Pending
-
2024
- 2024-03-18 US US18/608,389 patent/US20240360099A1/en active Pending
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