|
US5892019A
(en)
|
1987-07-15 |
1999-04-06 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Production of a single-gene-encoded immunoglobulin
|
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
|
US5573924A
(en)
|
1992-09-08 |
1996-11-12 |
Immunex Corporation |
CD27 ligand
|
|
DE19747418C1
(de)
|
1997-10-27 |
1999-07-15 |
Deutsches Krebsforsch |
Inhibitor-Protein des wnt-Signalwegs
|
|
US6500633B1
(en)
|
2000-04-26 |
2002-12-31 |
Atairgin Technologies, Inc. |
Method of detecting carcinomas
|
|
US20030148321A1
(en)
|
2001-08-24 |
2003-08-07 |
Iris Pecker |
Methods and kits for diagnosing and monitoring hematopoietic cancers
|
|
EP1470247A2
(en)
|
2001-11-05 |
2004-10-27 |
Deutsches Krebsforschungszentrum |
Novel genetic markers for leukemias
|
|
US7261892B2
(en)
|
2001-11-27 |
2007-08-28 |
Celltech R&D Limited |
Methods for diagnosis and treatment of epithelial-derived cancers
|
|
WO2003046581A2
(en)
|
2001-11-27 |
2003-06-05 |
Oxford Glycosciences (Uk) Ltd |
Methods for diagnosis and treatment of epithelial-derived cancers,such as colorectal cancers and kidney cancers
|
|
US8404716B2
(en)
|
2002-10-15 |
2013-03-26 |
Celgene Corporation |
Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
|
|
US8039218B2
(en)
|
2002-11-14 |
2011-10-18 |
John Wayne Cancer Institute |
Detection of cancer cells in body fluids
|
|
EP1594542B1
(en)
|
2003-02-20 |
2010-06-30 |
Seattle Genetics, Inc. |
Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer
|
|
US20080025989A1
(en)
*
|
2003-02-20 |
2008-01-31 |
Seattle Genetics, Inc. |
Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
|
|
KR20050116392A
(ko)
|
2003-03-24 |
2005-12-12 |
지모제넥틱스, 인코포레이티드 |
항-il-22ra 항체 및 결합 파트너 및 염증에 있어서의사용 방법
|
|
EA010350B1
(ru)
|
2004-06-03 |
2008-08-29 |
Новиммун С.А. |
Антитела против cd3 и способы их применения
|
|
US7641903B2
(en)
|
2004-10-15 |
2010-01-05 |
Seattle Genetics, Inc. |
Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
|
|
US8337838B2
(en)
|
2004-10-15 |
2012-12-25 |
Seattle Genetics, Inc. |
Anti-CD70 antibody and its use for the treatment and prevention of cancer and immune disorders
|
|
CA2583208C
(en)
|
2004-10-15 |
2015-08-25 |
Seattle Genetics, Inc. |
Anti-cd70 antibody and its use for the treatment and prevention of cancer and immune disorders
|
|
BRPI0516975A
(pt)
|
2004-10-22 |
2008-09-30 |
Zymogenetics Inc |
anticorpo ou seu fragmento de ligação a antìgeno, composição farmacêutica, imunoconjugado, hibridoma, anticorpo monoclonal, e, uso de um anticorpo ou seu fragmento de ligação a antìgeno
|
|
JP5122441B2
(ja)
|
2005-04-19 |
2013-01-16 |
シアトル ジェネティックス, インコーポレイテッド |
ヒト化抗cd70結合剤およびその使用
|
|
EP1872124A4
(en)
|
2005-04-19 |
2008-06-11 |
Prediction Sciences Llc |
DIAGNOSTIC MARKERS FOR THE TREATMENT AND EVOLUTION OF BREAST CANCER AND METHODS OF USE
|
|
WO2007011856A2
(en)
|
2005-07-15 |
2007-01-25 |
The Trustees Of Columbia University In The City Of New York |
Compositions and methods for differential diagnosis of chronic lymphocytic leukemia
|
|
AU2006294663B2
(en)
|
2005-09-26 |
2012-03-22 |
Medarex, Inc. |
Human monoclonal antibodies to CD70
|
|
US7723477B2
(en)
|
2005-10-31 |
2010-05-25 |
Oncomed Pharmaceuticals, Inc. |
Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
|
|
EP2418223A3
(en)
|
2006-06-12 |
2013-01-16 |
Emergent Product Development Seattle, LLC |
Single-chain multivalent binding proteins with effector function
|
|
CA2699837C
(en)
|
2006-12-01 |
2017-06-13 |
Seattle Genetics, Inc. |
Variant target binding agents and uses thereof
|
|
IN2009KN02404A
(enExample)
|
2006-12-14 |
2015-08-07 |
Medarex Inc |
|
|
KR100807069B1
(ko)
|
2007-09-21 |
2008-02-25 |
고려대학교 산학협력단 |
암 치료용 의약 조성물
|
|
EP2217223A2
(en)
|
2007-11-05 |
2010-08-18 |
Novartis AG |
Methods and compositions for measuring wnt activation and for treating wnt-related cancers
|
|
GB2461546B
(en)
|
2008-07-02 |
2010-07-07 |
Argen X Bv |
Antigen binding polypeptides
|
|
WO2010014948A1
(en)
|
2008-08-01 |
2010-02-04 |
The University Of Utah Research Foundation |
Methods of treatment using wnt inhibitors
|
|
WO2010019921A2
(en)
|
2008-08-15 |
2010-02-18 |
The Regents Of The University Of California |
Biomarkers for diagnosis and treatment of chronic lymphocytic leukemia
|
|
NZ592338A
(en)
|
2008-09-26 |
2012-11-30 |
Oncomed Pharm Inc |
Frizzled-binding agents and uses thereof
|
|
JP5748653B2
(ja)
|
2009-04-10 |
2015-07-15 |
協和発酵キリン株式会社 |
抗tim−3抗体を用いた血液腫瘍治療法
|
|
DK2987487T3
(da)
|
2009-08-10 |
2020-12-07 |
Samumed Llc |
Indazolinhibitorer af wnt-signalvejen og terapeutiske anvendelser deraf
|
|
WO2011035433A1
(en)
|
2009-09-23 |
2011-03-31 |
University Health Network |
Selected strains on serum-free growth media for proteomics analysis of lung cancer biomarkers
|
|
CN102665759B
(zh)
|
2009-11-19 |
2015-09-30 |
默克雪兰诺有限公司 |
人源化抗il-22ra抗体
|
|
AU2010339359A1
(en)
|
2009-12-29 |
2012-07-26 |
Kyowa Hakko Kirin Co., Ltd. |
Anti-CD27 antibody
|
|
GB2476681B
(en)
|
2010-01-04 |
2012-04-04 |
Argen X Bv |
Humanized camelid VH, VK and VL immunoglobulin domains
|
|
CN103079644B
(zh)
|
2010-06-11 |
2017-02-15 |
协和发酵麒麟株式会社 |
抗tim‑3抗体
|
|
ES2714716T3
(es)
|
2011-01-19 |
2019-05-29 |
Cantargia Ab |
Anticuerpos anti-IL1RAP y su uso para el tratamiento de tumores sólidos
|
|
HUE039849T2
(hu)
|
2011-03-16 |
2019-02-28 |
Argenx Bvba |
CD70 elleni ellenanyagok
|
|
WO2013006490A2
(en)
|
2011-07-01 |
2013-01-10 |
Cellerant Therapeutics, Inc. |
Antibodies that specifically bind to tim3
|
|
BR112014006822B1
(pt)
|
2011-09-22 |
2021-05-18 |
Amgen Inc. |
Proteína de ligação ao antígeno cd27l, composição compreendendo uma proteína de ligação ao antígeno cd27l, ácido nucleico isolado, vetor de expressão, célula hospedeira recombinante procariótica, método de preparação de um conjugado de droga e anticorpo cd27l e uso de uma proteína de ligação ao antígeno cd27l
|
|
WO2013093508A2
(en)
|
2011-12-22 |
2013-06-27 |
Oslo University Hospital Hf |
Wnt pathway inhibitors
|
|
MY175224A
(en)
|
2012-03-15 |
2020-06-16 |
Janssen Biotech Inc |
Human anti-cd27 antibodies, methods, and uses
|
|
JP6194350B2
(ja)
|
2012-03-21 |
2017-09-06 |
エリテック・ファルマ |
急性骨髄性白血病(aml)の処置のための薬剤
|
|
US9801851B2
(en)
|
2012-05-23 |
2017-10-31 |
St. Jude Children's Research Hospital |
Methods and compositions for the treatment of BCR-ABL positive lymphoblastic leukemias
|
|
JP6081582B2
(ja)
|
2012-06-15 |
2017-02-15 |
キュアジェニックス インコーポレイテッド |
Wntシグナリング阻害剤、組成物およびその用途としての化合物
|
|
EP2890711B1
(en)
|
2012-08-31 |
2017-01-04 |
Argen-X Nv |
Method for producing antibody molecules having inter-species, intra-target cross-reactivity
|
|
WO2014045101A1
(en)
|
2012-09-21 |
2014-03-27 |
Cellzome Gmbh |
Tetrazolo quinoxaline derivatives as tankyrase inhibitors
|
|
EP2935334A4
(en)
|
2012-12-21 |
2016-10-26 |
Cellerant Therapeutics Inc |
ANTIBODIES THAT FIX TO MEMBRANE-RELATED IL1 RAPID
|
|
HUE033626T2
(en)
|
2013-02-14 |
2017-12-28 |
Bristol Myers Squibb Co |
Tubulysin compounds, methods of preparation and use
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
EP3116544A4
(en)
|
2014-03-11 |
2017-08-23 |
The Board of Trustees of the Leland Stanford Junior University |
Anti sirp-alpha antibodies and bi-specific macrophage enhancing antibodies
|
|
US10391168B1
(en)
|
2014-08-22 |
2019-08-27 |
University Of Bern |
Anti-CD70 combination therapy
|
|
US20160200815A1
(en)
|
2015-01-05 |
2016-07-14 |
Jounce Therapeutics, Inc. |
Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof
|
|
TWI717375B
(zh)
*
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
|
EA039859B1
(ru)
|
2015-07-31 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
US20180244792A1
(en)
*
|
2015-09-10 |
2018-08-30 |
University Of Pittsburgh - Of The Commonwealth System Of Higher Education |
Anti-fibrotic effect of cd70
|
|
MY198562A
(en)
*
|
2015-11-03 |
2023-09-05 |
Janssen Biotech Inc |
Antibodies specifically binding pd-1 and their uses
|
|
EP3442584B1
(en)
|
2016-03-15 |
2021-07-28 |
Seagen Inc. |
Combinations of pbd-based antibody drug conjugates with bcl-2 inhibitors
|
|
GB2567613A
(en)
|
2017-06-16 |
2019-04-24 |
Argenx Bvba |
Treatment for acute myeloid leukaemia
|
|
GB201800649D0
(en)
|
2018-01-16 |
2018-02-28 |
Argenx Bvba |
CD70 Combination Therapy
|
|
TWI848030B
(zh)
|
2018-12-18 |
2024-07-11 |
比利時商阿根思公司 |
Cd70組合治療
|
|
US20220136068A1
(en)
|
2019-03-06 |
2022-05-05 |
The Regents Of The University Of Colorado, A Body Corporate |
Methods of detecting and treating venetoclax-resistant acute myeloid leukemia
|
|
IL300996A
(en)
|
2020-08-29 |
2023-04-01 |
argenx BV |
Treatment method for patients with reduced sensitivity to BCL-2 inhibitor
|
|
AU2021358768A1
(en)
|
2020-10-06 |
2023-05-18 |
The Regents Of The University Of Colorado, A Body Corporate |
Subject-specific treatments for venetoclax-resistant acute myeloid leukemia
|