JP2024028452A5 - - Google Patents
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- JP2024028452A5 JP2024028452A5 JP2024002401A JP2024002401A JP2024028452A5 JP 2024028452 A5 JP2024028452 A5 JP 2024028452A5 JP 2024002401 A JP2024002401 A JP 2024002401A JP 2024002401 A JP2024002401 A JP 2024002401A JP 2024028452 A5 JP2024028452 A5 JP 2024028452A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- amino acid
- residue
- residues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 39
- 229920001184 polypeptide Polymers 0.000 claims 37
- 102000004196 processed proteins & peptides Human genes 0.000 claims 37
- 150000001413 amino acids Chemical class 0.000 claims 17
- 230000004075 alteration Effects 0.000 claims 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 102000005593 Endopeptidases Human genes 0.000 claims 3
- 108010059378 Endopeptidases Proteins 0.000 claims 3
- 108010061711 Gliadin Proteins 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 208000015943 Coeliac disease Diseases 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161521899P | 2011-08-10 | 2011-08-10 | |
| US61/521,899 | 2011-08-10 | ||
| JP2019052599A JP2019162107A (ja) | 2011-08-10 | 2019-03-20 | セリアックスプルー病を治療するための組成物および方法 |
| JP2021048356A JP2021094031A (ja) | 2011-08-10 | 2021-03-23 | セリアックスプルー病を治療するための組成物および方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021048356A Division JP2021094031A (ja) | 2011-08-10 | 2021-03-23 | セリアックスプルー病を治療するための組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024028452A JP2024028452A (ja) | 2024-03-04 |
| JP2024028452A5 true JP2024028452A5 (https=) | 2024-10-23 |
Family
ID=46690751
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014525175A Active JP6342802B2 (ja) | 2011-08-10 | 2012-08-10 | セリアックスプルー病を治療するための組成物および方法 |
| JP2017133615A Active JP6502428B2 (ja) | 2011-08-10 | 2017-07-07 | セリアックスプルー病を治療するための組成物および方法 |
| JP2019052599A Pending JP2019162107A (ja) | 2011-08-10 | 2019-03-20 | セリアックスプルー病を治療するための組成物および方法 |
| JP2021048356A Pending JP2021094031A (ja) | 2011-08-10 | 2021-03-23 | セリアックスプルー病を治療するための組成物および方法 |
| JP2024002401A Pending JP2024028452A (ja) | 2011-08-10 | 2024-01-11 | セリアックスプルー病を治療するための組成物および方法 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014525175A Active JP6342802B2 (ja) | 2011-08-10 | 2012-08-10 | セリアックスプルー病を治療するための組成物および方法 |
| JP2017133615A Active JP6502428B2 (ja) | 2011-08-10 | 2017-07-07 | セリアックスプルー病を治療するための組成物および方法 |
| JP2019052599A Pending JP2019162107A (ja) | 2011-08-10 | 2019-03-20 | セリアックスプルー病を治療するための組成物および方法 |
| JP2021048356A Pending JP2021094031A (ja) | 2011-08-10 | 2021-03-23 | セリアックスプルー病を治療するための組成物および方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (7) | US9289473B2 (https=) |
| EP (3) | EP4023243A3 (https=) |
| JP (5) | JP6342802B2 (https=) |
| CA (1) | CA2882502A1 (https=) |
| CY (1) | CY1120877T1 (https=) |
| DK (1) | DK2718434T3 (https=) |
| ES (2) | ES2667418T3 (https=) |
| HR (1) | HRP20180687T1 (https=) |
| HU (1) | HUE037870T2 (https=) |
| LT (1) | LT2718434T (https=) |
| NO (1) | NO2718434T3 (https=) |
| PL (2) | PL3400958T3 (https=) |
| PT (1) | PT2718434T (https=) |
| RS (1) | RS57234B1 (https=) |
| SI (1) | SI2718434T1 (https=) |
| SM (1) | SMT201800249T1 (https=) |
| TR (1) | TR201806885T4 (https=) |
| WO (1) | WO2013023151A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6342802B2 (ja) | 2011-08-10 | 2018-06-13 | ザ ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャライゼーションＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｗａｓｈｉｎｇｔｏｎ Ｔｈｒｏｕｇｈ Ｉｔｓ Ｃｅｎｔｅｒ Ｆｏｒ Ｃｏｍｍｅｒｃｉａｌｉｚａｔｉｏｎ | セリアックスプルー病を治療するための組成物および方法 |
| WO2015023728A1 (en) | 2013-08-14 | 2015-02-19 | University Of Washington Through Its Center For Commercialization | Compositions and methods for treating celiac sprue disease |
| EP3081942A1 (en) * | 2015-04-17 | 2016-10-19 | Roche Diagniostics GmbH | Pressure transmission liquid for cellular analyzer, cellular analyzer and method for analyzing a liquid cellular sample |
| HK1245129A1 (zh) | 2015-06-08 | 2018-08-24 | University Of Washington | 治疗腹腔疾病的组合物及方法 |
| US11396648B2 (en) * | 2016-12-22 | 2022-07-26 | Ew Nutrition Gmbh | Stable protease variants |
| WO2020087017A1 (en) * | 2018-10-26 | 2020-04-30 | The Regents Of The University Of California | Use of proteolytic enzymes to enhance protein bioavailability |
| US20240226248A9 (en) * | 2018-10-26 | 2024-07-11 | The Regents Of The University Of California | Methods and compositions for improving protein hydrolysis |
| US20250064903A1 (en) | 2020-10-30 | 2025-02-27 | University Of Washington | Compositions and methods for treating celiac sprue disease |
| AU2023213894B2 (en) | 2022-01-26 | 2025-04-10 | Digestiva, Inc. | Blood glucose stabilizing methods and compositions |
| WO2025068987A1 (en) | 2023-09-28 | 2025-04-03 | Takeda Pharmaceutical Company Limited | A method of producing a kumamolisin-as polypeptide |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2688229B1 (fr) | 1992-03-09 | 1995-06-23 | Ulice Soc | Procede de synthese enzymatique d'esters alkyliques de peptides, produits ainsi obtenus et utilisation desdits produits. |
| JP2002078489A (ja) * | 2000-09-04 | 2002-03-19 | Daiwa Kasei Kk | セリン残基が活性発現に関与する新規酸性プロテアーゼ |
| DE60336754D1 (de) | 2002-02-14 | 2011-05-26 | Univ R | Enzymbehandlung von nahrungsmitteln für zöliakie-sprue |
| US8143210B2 (en) | 2002-02-14 | 2012-03-27 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for celiac sprue |
| US7320788B2 (en) | 2002-02-14 | 2008-01-22 | The Board Of Trustees Of The Leland Stanford Junior University | Enzyme treatment of foodstuffs for Celiac Sprue |
| US7265093B2 (en) | 2002-05-14 | 2007-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for Celiac Sprue |
| US7462688B2 (en) | 2002-05-14 | 2008-12-09 | The Board Of Trustees Of The Leland Stanford Junior University | Peptides for diagnostic and therapeutic methods for celiac sprue |
| US7202216B2 (en) | 2002-05-14 | 2007-04-10 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for celiac sprue |
| US7605150B2 (en) | 2002-05-14 | 2009-10-20 | The Board Of Trustees Of The Leland Stanford Junior University | Drug therapy for Celiac Sprue |
| EP1563300B1 (en) | 2002-11-20 | 2012-04-18 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnostic method for celiac sprue |
| US7579313B2 (en) | 2003-11-18 | 2009-08-25 | The Board Of Trustees Of The Leland Stanford Junior University | Transglutaminase inhibitors and methods of use thereof |
| US7534426B2 (en) | 2004-04-26 | 2009-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Glutenase enzyme assays |
| US7628985B2 (en) | 2004-04-26 | 2009-12-08 | The Board Of Regents Of The Leland Stanford Junior University | Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis |
| US7563864B2 (en) | 2004-04-26 | 2009-07-21 | Celiac Sprue Research Foundation | Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten |
| EP1600141B1 (en) | 2004-05-24 | 2013-04-17 | 3M Deutschland GmbH | Collagenolytic active enzyme containing compositions for the treatment of dental caries |
| EP1726643A1 (en) * | 2005-05-27 | 2006-11-29 | Direvo Biotech AG | Method for the provision, identification and selection of proteases with altered sensitivity to activity-modulating substances |
| ES2616231T3 (es) | 2008-08-21 | 2017-06-12 | Immunogenics Llc | Formulación para administración oral de proteínas |
| JP6342802B2 (ja) * | 2011-08-10 | 2018-06-13 | ザ ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャライゼーションＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｗａｓｈｉｎｇｔｏｎ Ｔｈｒｏｕｇｈ Ｉｔｓ Ｃｅｎｔｅｒ Ｆｏｒ Ｃｏｍｍｅｒｃｉａｌｉｚａｔｉｏｎ | セリアックスプルー病を治療するための組成物および方法 |
| EP2788018B1 (en) | 2011-12-06 | 2016-06-29 | Fondazione Istituto Insubrico di Ricerca per la Vita | New proteases able to hydrolyze gluten peptides and proteins at acidic ph, from the actinomycete actinoallomurus |
| WO2015023728A1 (en) | 2013-08-14 | 2015-02-19 | University Of Washington Through Its Center For Commercialization | Compositions and methods for treating celiac sprue disease |
| HK1245129A1 (zh) | 2015-06-08 | 2018-08-24 | University Of Washington | 治疗腹腔疾病的组合物及方法 |
-
2012
- 2012-08-10 JP JP2014525175A patent/JP6342802B2/ja active Active
- 2012-08-10 DK DK12748354.3T patent/DK2718434T3/en active
- 2012-08-10 HU HUE12748354A patent/HUE037870T2/hu unknown
- 2012-08-10 ES ES12748354.3T patent/ES2667418T3/es active Active
- 2012-08-10 ES ES18162586T patent/ES2896489T3/es active Active
- 2012-08-10 PT PT127483543T patent/PT2718434T/pt unknown
- 2012-08-10 LT LTEP12748354.3T patent/LT2718434T/lt unknown
- 2012-08-10 EP EP21187810.3A patent/EP4023243A3/en active Pending
- 2012-08-10 CA CA2882502A patent/CA2882502A1/en active Pending
- 2012-08-10 EP EP18162586.4A patent/EP3400958B1/en active Active
- 2012-08-10 US US14/131,601 patent/US9289473B2/en active Active
- 2012-08-10 EP EP12748354.3A patent/EP2718434B1/en active Active
- 2012-08-10 HR HRP20180687TT patent/HRP20180687T1/hr unknown
- 2012-08-10 RS RS20180609A patent/RS57234B1/sr unknown
- 2012-08-10 NO NO12748354A patent/NO2718434T3/no unknown
- 2012-08-10 WO PCT/US2012/050364 patent/WO2013023151A2/en not_active Ceased
- 2012-08-10 TR TR2018/06885T patent/TR201806885T4/tr unknown
- 2012-08-10 PL PL18162586T patent/PL3400958T3/pl unknown
- 2012-08-10 SI SI201231269T patent/SI2718434T1/en unknown
- 2012-08-10 PL PL12748354T patent/PL2718434T3/pl unknown
- 2012-08-10 SM SM20180249T patent/SMT201800249T1/it unknown
-
2016
- 2016-01-26 US US15/006,341 patent/US9707280B2/en active Active
-
2017
- 2017-06-26 US US15/633,065 patent/US9925249B2/en active Active
- 2017-07-07 JP JP2017133615A patent/JP6502428B2/ja active Active
-
2018
- 2018-02-14 US US15/896,536 patent/US10149892B2/en active Active
- 2018-06-21 CY CY181100648T patent/CY1120877T1/el unknown
- 2018-11-28 US US16/203,109 patent/US10874720B2/en active Active
-
2019
- 2019-03-20 JP JP2019052599A patent/JP2019162107A/ja active Pending
-
2020
- 2020-12-07 US US17/114,294 patent/US20210085761A1/en not_active Abandoned
-
2021
- 2021-03-23 JP JP2021048356A patent/JP2021094031A/ja active Pending
-
2023
- 2023-11-20 US US18/513,879 patent/US12544430B2/en active Active
-
2024
- 2024-01-11 JP JP2024002401A patent/JP2024028452A/ja active Pending
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