LT2718434T - Kompozicijos ir būdai, skirti celiakijos gydymui - Google Patents

Kompozicijos ir būdai, skirti celiakijos gydymui

Info

Publication number
LT2718434T
LT2718434T LTEP12748354.3T LT12748354T LT2718434T LT 2718434 T LT2718434 T LT 2718434T LT 12748354 T LT12748354 T LT 12748354T LT 2718434 T LT2718434 T LT 2718434T
Authority
LT
Lithuania
Prior art keywords
compositions
methods
celiac sprue
treating celiac
sprue disease
Prior art date
Application number
LTEP12748354.3T
Other languages
English (en)
Inventor
Justin Siegel
David Baker
Sydney GORDON
Ingrid PULTZ
Elizabeth Stanley
Sarah WOLF
Original Assignee
University Of Washington Through Its Center For Commercialization
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Washington Through Its Center For Commercialization filed Critical University Of Washington Through Its Center For Commercialization
Publication of LT2718434T publication Critical patent/LT2718434T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
LTEP12748354.3T 2011-08-10 2012-08-10 Kompozicijos ir būdai, skirti celiakijos gydymui LT2718434T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161521899P 2011-08-10 2011-08-10
PCT/US2012/050364 WO2013023151A2 (en) 2011-08-10 2012-08-10 Compositions and methods for treating celiac sprue disease

Publications (1)

Publication Number Publication Date
LT2718434T true LT2718434T (lt) 2018-08-10

Family

ID=46690751

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP12748354.3T LT2718434T (lt) 2011-08-10 2012-08-10 Kompozicijos ir būdai, skirti celiakijos gydymui

Country Status (17)

Country Link
US (7) US9289473B2 (lt)
EP (3) EP4023243A3 (lt)
JP (5) JP6342802B2 (lt)
CA (1) CA2882502A1 (lt)
CY (1) CY1120877T1 (lt)
DK (1) DK2718434T3 (lt)
ES (2) ES2896489T3 (lt)
HR (1) HRP20180687T1 (lt)
HU (1) HUE037870T2 (lt)
LT (1) LT2718434T (lt)
NO (1) NO2718434T3 (lt)
PL (2) PL3400958T3 (lt)
PT (1) PT2718434T (lt)
RS (1) RS57234B1 (lt)
SI (1) SI2718434T1 (lt)
TR (1) TR201806885T4 (lt)
WO (1) WO2013023151A2 (lt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4023243A3 (en) 2011-08-10 2022-09-14 University of Washington through its Center for Commercialization Compositions and methods for treating celiac sprue disease
EP4008340A1 (en) 2013-08-14 2022-06-08 University of Washington Through Its Center for Commercialization Compositions for treating celiac sprue disease
EP3081942A1 (en) * 2015-04-17 2016-10-19 Roche Diagniostics GmbH Pressure transmission liquid for cellular analyzer, cellular analyzer and method for analyzing a liquid cellular sample
WO2016200880A1 (en) * 2015-06-08 2016-12-15 University Of Washington Compositions and methods for treating celiac sprue disease
MX2019007287A (es) 2016-12-22 2019-09-27 Ew Nutrition Gmbh Variantes de proteasas estables.
WO2020087017A1 (en) * 2018-10-26 2020-04-30 The Regents Of The University Of California Use of proteolytic enzymes to enhance protein bioavailability
AU2021368118A1 (en) 2020-10-30 2023-05-11 The Regents Of The University Of California Compositions and methods for treating celiac sprue disease
AU2023213894A1 (en) 2022-01-26 2024-08-15 Digestiva, Inc. Blood glucose stabilizing methods and compositions

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2688229B1 (fr) 1992-03-09 1995-06-23 Ulice Soc Procede de synthese enzymatique d'esters alkyliques de peptides, produits ainsi obtenus et utilisation desdits produits.
JP2002078489A (ja) * 2000-09-04 2002-03-19 Daiwa Kasei Kk セリン残基が活性発現に関与する新規酸性プロテアーゼ
US8143210B2 (en) 2002-02-14 2012-03-27 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
DE60336754D1 (de) 2002-02-14 2011-05-26 Univ R Enzymbehandlung von nahrungsmitteln für zöliakie-sprue
US7320788B2 (en) 2002-02-14 2008-01-22 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for Celiac Sprue
US7202216B2 (en) 2002-05-14 2007-04-10 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for celiac sprue
US7265093B2 (en) 2002-05-14 2007-09-04 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for Celiac Sprue
US7462688B2 (en) 2002-05-14 2008-12-09 The Board Of Trustees Of The Leland Stanford Junior University Peptides for diagnostic and therapeutic methods for celiac sprue
CA2487247A1 (en) 2002-05-14 2003-11-27 The Board Of Trustees Of The Leland Stanford Junior University Drug therapy for celiac sprue
EP1563300B1 (en) 2002-11-20 2012-04-18 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic method for celiac sprue
US7579313B2 (en) 2003-11-18 2009-08-25 The Board Of Trustees Of The Leland Stanford Junior University Transglutaminase inhibitors and methods of use thereof
US7563864B2 (en) 2004-04-26 2009-07-21 Celiac Sprue Research Foundation Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten
US7628985B2 (en) 2004-04-26 2009-12-08 The Board Of Regents Of The Leland Stanford Junior University Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis
US7534426B2 (en) 2004-04-26 2009-05-19 The Board Of Trustees Of The Leland Stanford Junior University Glutenase enzyme assays
EP1600141B1 (en) 2004-05-24 2013-04-17 3M Deutschland GmbH Collagenolytic active enzyme containing compositions for the treatment of dental caries
EP1726643A1 (en) * 2005-05-27 2006-11-29 Direvo Biotech AG Method for the provision, identification and selection of proteases with altered sensitivity to activity-modulating substances
CA2733514C (en) 2008-08-21 2017-10-24 Alvine Pharmaceuticals, Inc. Formulation for oral administration of proteins
EP4023243A3 (en) * 2011-08-10 2022-09-14 University of Washington through its Center for Commercialization Compositions and methods for treating celiac sprue disease
CA2852365C (en) 2011-12-06 2021-01-26 Fondazione Istituto Insubrico Di Ricerca Per La Vita Proteases able to hydrolyze gluten peptides and proteins at acidic ph, from the actinomycete actinoallomurus.
EP4008340A1 (en) 2013-08-14 2022-06-08 University of Washington Through Its Center for Commercialization Compositions for treating celiac sprue disease

Also Published As

Publication number Publication date
CY1120877T1 (el) 2019-12-11
US20210085761A1 (en) 2021-03-25
US20180185458A1 (en) 2018-07-05
US20160166656A1 (en) 2016-06-16
EP4023243A3 (en) 2022-09-14
JP2014529399A (ja) 2014-11-13
US10149892B2 (en) 2018-12-11
JP6342802B2 (ja) 2018-06-13
US20240207376A1 (en) 2024-06-27
DK2718434T3 (en) 2018-07-09
US9707280B2 (en) 2017-07-18
US20190083585A1 (en) 2019-03-21
WO2013023151A2 (en) 2013-02-14
JP2024028452A (ja) 2024-03-04
US9925249B2 (en) 2018-03-27
RS57234B1 (sr) 2018-07-31
US20140178355A1 (en) 2014-06-26
HUE037870T2 (hu) 2018-09-28
JP6502428B2 (ja) 2019-04-17
CA2882502A1 (en) 2013-02-14
US9289473B2 (en) 2016-03-22
EP3400958B1 (en) 2021-08-04
JP2017221201A (ja) 2017-12-21
US10874720B2 (en) 2020-12-29
EP4023243A2 (en) 2022-07-06
PT2718434T (pt) 2018-05-21
US20170296633A1 (en) 2017-10-19
NO2718434T3 (lt) 2018-08-25
EP2718434B1 (en) 2018-03-28
EP2718434A2 (en) 2014-04-16
SI2718434T1 (en) 2018-06-29
HRP20180687T1 (hr) 2018-06-15
PL2718434T3 (pl) 2018-08-31
ES2896489T3 (es) 2022-02-24
JP2019162107A (ja) 2019-09-26
PL3400958T3 (pl) 2022-01-03
EP3400958A1 (en) 2018-11-14
ES2667418T3 (es) 2018-05-10
TR201806885T4 (tr) 2018-06-21
WO2013023151A3 (en) 2013-07-18
JP2021094031A (ja) 2021-06-24

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