JP2024540639A5 - - Google Patents
Info
- Publication number
- JP2024540639A5 JP2024540639A5 JP2024530470A JP2024530470A JP2024540639A5 JP 2024540639 A5 JP2024540639 A5 JP 2024540639A5 JP 2024530470 A JP2024530470 A JP 2024530470A JP 2024530470 A JP2024530470 A JP 2024530470A JP 2024540639 A5 JP2024540639 A5 JP 2024540639A5
- Authority
- JP
- Japan
- Prior art keywords
- tale
- effector
- activator
- protein according
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163282453P | 2021-11-23 | 2021-11-23 | |
| US63/282,453 | 2021-11-23 | ||
| DKPA202270104 | 2022-03-15 | ||
| DKPA202270104 | 2022-03-15 | ||
| PCT/EP2022/082950 WO2023094435A1 (en) | 2021-11-23 | 2022-11-23 | New tale protein scaffolds with improved on-target/off-target activity ratios |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024540639A JP2024540639A (ja) | 2024-10-31 |
| JP2024540639A5 true JP2024540639A5 (https=) | 2025-12-01 |
Family
ID=84487474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024530470A Pending JP2024540639A (ja) | 2021-11-23 | 2022-11-23 | オンターゲット／オフターゲット活性比が改善された新規ｔａｌｅタンパク質スキャフォールド |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250002945A1 (https=) |
| EP (1) | EP4437091A1 (https=) |
| JP (1) | JP2024540639A (https=) |
| KR (1) | KR20240110844A (https=) |
| AU (1) | AU2022395500A1 (https=) |
| CA (1) | CA3238700A1 (https=) |
| IL (1) | IL312721A (https=) |
| MX (1) | MX2024006051A (https=) |
| WO (1) | WO2023094435A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4583890A1 (en) * | 2022-09-09 | 2025-07-16 | Iovance Biotherapeutics, Inc. | Processes for generating til products using pd-1/tigit talen double knockdown |
| WO2025181336A1 (en) | 2024-03-01 | 2025-09-04 | Cellectis Sa | Compositions and methods for hbb-editing in hspc |
| WO2025211767A1 (ko) * | 2024-04-02 | 2025-10-09 | 재단법인 아산사회복지재단 | 핵산 결합 단백질 및 ssda를 포함하는 융합단백질 및 이의 용도 |
| WO2026046724A1 (en) | 2024-08-30 | 2026-03-05 | Cellectis Sa | Tale protein scaffolds involving fusions of monopartite and bipartite nls |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880635B1 (en) | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4921757A (en) | 1985-04-26 | 1990-05-01 | Massachusetts Institute Of Technology | System for delayed and pulsed release of biologically active substances |
| US4920016A (en) | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
| JPH0825869B2 (ja) | 1987-02-09 | 1996-03-13 | 株式会社ビタミン研究所 | 抗腫瘍剤包埋リポソ−ム製剤 |
| US4911928A (en) | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
| US4917951A (en) | 1987-07-28 | 1990-04-17 | Micro-Pak, Inc. | Lipid vesicles formed of surfactants and steroids |
| WO2011072246A2 (en) | 2009-12-10 | 2011-06-16 | Regents Of The University Of Minnesota | Tal effector-mediated dna modification |
| CA3111953C (en) | 2011-04-05 | 2023-10-24 | Cellectis | Method for the generation of compact tale-nucleases and uses thereof |
| EP2737066B1 (en) | 2011-07-29 | 2017-11-08 | Cellectis | High throughput method for assembly and cloning polynucleotides comprising highly similar polynucleotidic modules |
| BR112014029417B1 (pt) | 2012-05-25 | 2023-03-07 | Cellectis | Método ex vivo para a preparação de células t para imunoterapia |
| US10378007B2 (en) * | 2012-09-03 | 2019-08-13 | Cellectis | Methods for modulating TAL specificity |
| ES2716867T3 (es) | 2013-05-31 | 2019-06-17 | Cellectis Sa | Endonucleasa de asentamiento LAGLIDADG que escinde el gen de receptor de células T alfa y usos de la misma |
-
2022
- 2022-11-23 EP EP22821976.2A patent/EP4437091A1/en active Pending
- 2022-11-23 MX MX2024006051A patent/MX2024006051A/es unknown
- 2022-11-23 JP JP2024530470A patent/JP2024540639A/ja active Pending
- 2022-11-23 US US18/712,640 patent/US20250002945A1/en active Pending
- 2022-11-23 IL IL312721A patent/IL312721A/en unknown
- 2022-11-23 CA CA3238700A patent/CA3238700A1/en active Pending
- 2022-11-23 KR KR1020247020471A patent/KR20240110844A/ko active Pending
- 2022-11-23 WO PCT/EP2022/082950 patent/WO2023094435A1/en not_active Ceased
- 2022-11-23 AU AU2022395500A patent/AU2022395500A1/en active Pending
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