JP2023554066A5 - - Google Patents

Info

Publication number
JP2023554066A5
JP2023554066A5 JP2023536584A JP2023536584A JP2023554066A5 JP 2023554066 A5 JP2023554066 A5 JP 2023554066A5 JP 2023536584 A JP2023536584 A JP 2023536584A JP 2023536584 A JP2023536584 A JP 2023536584A JP 2023554066 A5 JP2023554066 A5 JP 2023554066A5
Authority
JP
Japan
Prior art keywords
raav vector
vector according
promoter
plasma kallikrein
raav
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023536584A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023554066A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/000874 external-priority patent/WO2022130014A1/en
Publication of JP2023554066A publication Critical patent/JP2023554066A/ja
Publication of JP2023554066A5 publication Critical patent/JP2023554066A5/ja
Pending legal-status Critical Current

Links

JP2023536584A 2020-12-16 2021-12-15 血漿カリクレインの制御不全によって媒介される疾患の処置のための抗体のアデノ随伴ウイルスベクター送達 Pending JP2023554066A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063126300P 2020-12-16 2020-12-16
US63/126,300 2020-12-16
PCT/IB2021/000874 WO2022130014A1 (en) 2020-12-16 2021-12-15 Adeno associated viral vector delivery of antibodies for the treatment of disease mediated by dysregulated plasma kallikrein

Publications (2)

Publication Number Publication Date
JP2023554066A JP2023554066A (ja) 2023-12-26
JP2023554066A5 true JP2023554066A5 (https=) 2024-12-23

Family

ID=80461568

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023536584A Pending JP2023554066A (ja) 2020-12-16 2021-12-15 血漿カリクレインの制御不全によって媒介される疾患の処置のための抗体のアデノ随伴ウイルスベクター送達

Country Status (5)

Country Link
US (1) US20220186252A1 (https=)
EP (1) EP4263614A1 (https=)
JP (1) JP2023554066A (https=)
CN (1) CN116829595A (https=)
WO (1) WO2022130014A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116790615B (zh) * 2023-07-11 2024-11-22 康霖生物科技(杭州)有限公司 一种用于过敏性疾病的基因治疗载体核酸构建体及其使用方法
GB202402816D0 (en) * 2024-02-28 2024-04-10 Imperial College Innovations Ltd Self-amplifying RNA molecule

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136597A (en) 1997-09-18 2000-10-24 The Salk Institute For Biological Studies RNA export element
US7419829B2 (en) 2000-10-06 2008-09-02 Oxford Biomedica (Uk) Limited Vector system
US7575924B2 (en) 2000-11-13 2009-08-18 Research Development Foundation Methods and compositions relating to improved lentiviral vectors and their applications
RU2305708C2 (ru) 2001-10-02 2007-09-10 Энститю Клейтон Де Ля Решерш Рекомбинантный лентивирусный вектор, клетка-хозяин, трансдуцированная лентивирусным вектором, способ ее трансдукции и применение
DK1737966T3 (da) 2004-04-02 2012-07-09 Univ Texas Cancerspecifik promotorer
US8865881B2 (en) 2011-02-22 2014-10-21 California Institute Of Technology Delivery of proteins using adeno-associated virus (AAV) vectors
GB201206455D0 (en) 2012-04-12 2012-05-30 Royal Holloway & Bedford New College Gene expression
AU2014240045A1 (en) 2013-03-15 2015-09-10 Dyax Corp. Anti-plasma kallikrein antibodies
CA2906770A1 (en) 2013-03-15 2014-09-18 Vlp Biotech, Inc. Palivizumab epitope-based virus-like particles
WO2016100575A1 (en) 2014-12-16 2016-06-23 Board Of Regents Of The University Of Nebraska Gene therapy for juvenile batten disease
CL2014003590A1 (es) 2014-12-30 2015-07-10 Univ Chile Virus aav/xbp1s-ha, método de tratamiento genético y su uso en la optimizacion y mejoramiento de las capacidades cognitivas, de memoria y de aprendizaje.
MA41346A (fr) 2015-01-12 2017-11-21 Juno Therapeutics Inc Eléments régulateurs post-transcriptionnels d'hépatite modifiée
US10179918B2 (en) 2015-05-07 2019-01-15 Sangamo Therapeutics, Inc. Methods and compositions for increasing transgene activity
GB2547179A (en) 2015-10-26 2017-08-16 Quethera Ltd Genetic construct
EP3368672B1 (en) 2015-10-27 2020-11-25 Celltheon Corporation Chimeric post-transcriptional regulatory element
US20190161530A1 (en) 2016-04-07 2019-05-30 Bluebird Bio, Inc. Chimeric antigen receptor t cell compositions
MX2018014256A (es) 2016-05-20 2019-08-16 Harvard College Metodos de terapia genica para enfermedades y condiciones relacionadas con la edad.
CA3053534A1 (en) 2017-02-17 2018-08-23 Purdue Research Foundation Targeted ligand-payload based drug delivery for cell therapy
WO2020219868A1 (en) * 2019-04-24 2020-10-29 Regenxbio Inc. Fully-human post-translationally modified antibody therapeutics
WO2021081280A1 (en) * 2019-10-23 2021-04-29 Shire Human Genetic Therapies, Inc. Adeno-associated virus vectors based gene therapy for hereditary angioedema
US20230390418A1 (en) * 2020-10-29 2023-12-07 Regenxbio Inc. Vectorized factor xii antibodies and administration thereof

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