JP2023549125A5 - - Google Patents

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Publication number
JP2023549125A5
JP2023549125A5 JP2023527355A JP2023527355A JP2023549125A5 JP 2023549125 A5 JP2023549125 A5 JP 2023549125A5 JP 2023527355 A JP2023527355 A JP 2023527355A JP 2023527355 A JP2023527355 A JP 2023527355A JP 2023549125 A5 JP2023549125 A5 JP 2023549125A5
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JP
Japan
Prior art keywords
domain
editing complex
sequence
functional
overhang
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023527355A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023549125A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/058079 external-priority patent/WO2022098885A1/en
Publication of JP2023549125A publication Critical patent/JP2023549125A/ja
Publication of JP2023549125A5 publication Critical patent/JP2023549125A5/ja
Pending legal-status Critical Current

Links

JP2023527355A 2020-11-05 2021-11-04 プライム編集に基づく精密なゲノムの削除と置換方法 Pending JP2023549125A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063110304P 2020-11-05 2020-11-05
US63/110,304 2020-11-05
PCT/US2021/058079 WO2022098885A1 (en) 2020-11-05 2021-11-04 Precise genome deletion and replacement method based on prime editing

Publications (2)

Publication Number Publication Date
JP2023549125A JP2023549125A (ja) 2023-11-22
JP2023549125A5 true JP2023549125A5 (https=) 2024-11-13

Family

ID=81458283

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023527355A Pending JP2023549125A (ja) 2020-11-05 2021-11-04 プライム編集に基づく精密なゲノムの削除と置換方法

Country Status (6)

Country Link
US (1) US20240011055A1 (https=)
EP (1) EP4240840A4 (https=)
JP (1) JP2023549125A (https=)
CN (1) CN116829706A (https=)
AU (1) AU2021376350A1 (https=)
WO (1) WO2022098885A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4232583A1 (en) 2020-10-21 2023-08-30 Massachusetts Institute of Technology Systems, methods, and compositions for site-specific genetic engineering using programmable addition via site-specific targeting elements (paste)
US20250354177A1 (en) * 2022-05-30 2025-11-20 Wuhan University System and methods for duplicating target fragments
WO2024233655A1 (en) * 2023-05-08 2024-11-14 Prime Medicine, Inc. Genome editing compositions and methods for treatment of fragile x syndrome

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3472321A2 (en) * 2016-06-17 2019-04-24 Genesis Technologies Limited Crispr-cas system, materials and methods
WO2020191233A1 (en) * 2019-03-19 2020-09-24 The Broad Institute, Inc. Methods and compositions for editing nucleotide sequences
EP4085141A4 (en) * 2019-12-30 2024-03-06 The Broad Institute, Inc. GENOME EDITING USING REVERSE TRANSCRIPTASE FOR FULLY ACTIVE CRISPR COMPLEXES
IL297761A (en) * 2020-05-08 2022-12-01 Broad Inst Inc Methods and compositions for simultaneously editing two helices of a designated double-helix nucleotide sequence

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