JP2023543254A5 - - Google Patents
Info
- Publication number
- JP2023543254A5 JP2023543254A5 JP2023519165A JP2023519165A JP2023543254A5 JP 2023543254 A5 JP2023543254 A5 JP 2023543254A5 JP 2023519165 A JP2023519165 A JP 2023519165A JP 2023519165 A JP2023519165 A JP 2023519165A JP 2023543254 A5 JP2023543254 A5 JP 2023543254A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- pharmaceutically acceptable
- solvate
- unsubstituted
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063082695P | 2020-09-24 | 2020-09-24 | |
| US63/082,695 | 2020-09-24 | ||
| PCT/US2021/051670 WO2022066851A1 (en) | 2020-09-24 | 2021-09-23 | PYRIDO[4,3-b]INDOLE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023543254A JP2023543254A (ja) | 2023-10-13 |
| JP2023543254A5 true JP2023543254A5 (https=) | 2024-10-01 |
Family
ID=80846865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023519165A Pending JP2023543254A (ja) | 2020-09-24 | 2021-09-23 | ピリド［４，３－ｂ］インドール誘導体およびその医薬としての使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240018138A1 (https=) |
| EP (1) | EP4216940A4 (https=) |
| JP (1) | JP2023543254A (https=) |
| CN (1) | CN116209442A (https=) |
| AU (1) | AU2021349249A1 (https=) |
| CA (1) | CA3196153A1 (https=) |
| WO (1) | WO2022066851A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022137085A1 (en) | 2020-12-22 | 2022-06-30 | Novartis Ag | Indole derivatives useful in treating conditions associated with cgas |
| EP4496796A1 (en) * | 2022-03-22 | 2025-01-29 | Ventus Therapeutics U.S., Inc. | Hexahydropyrido[4,3-b]indolyl ketone derivatives useful as cgas modulators |
| AU2023409125A1 (en) * | 2022-12-21 | 2025-06-26 | Eli Lilly And Company | Azepino[4,5-b]indolone cgas inhibitors |
| AU2024326748A1 (en) | 2023-08-18 | 2026-04-02 | Katholieke Universiteit Leuven | 1,3-dihydro-2h-pyrrolo[3,4-c]quinoline derivatives as cgas inhibitors for the treatment of inflammatory and/or autoimmune diseases |
| CN119490508A (zh) * | 2023-08-21 | 2025-02-21 | 上海交通大学 | 一类螺环四氢-γ-咔啉衍生物的制备方法以及应用 |
| WO2025218659A1 (en) * | 2024-04-16 | 2025-10-23 | Insilico Medicine Ip Limited | Novel compounds as cyclic gmp-amp synthase inhibitor and uses thereof |
| WO2026026969A1 (zh) * | 2024-08-01 | 2026-02-05 | 杭州英创医药科技有限公司 | 作为cGAS抑制剂的化合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2424366B1 (en) * | 2009-04-29 | 2016-02-17 | Medivation Technologies, Inc. | Pyrido [4, 3-b]indoles and methods of use |
| EP3472162B1 (en) * | 2016-06-16 | 2021-11-17 | F. Hoffmann-La Roche AG | Heteroaryl estrogen receptor modulators and uses thereof |
| CN111511729A (zh) * | 2017-12-19 | 2020-08-07 | 默克专利股份公司 | Tlr7/8拮抗剂及其用途 |
| BR112020016008A2 (pt) * | 2018-02-05 | 2020-12-15 | The Rockefeller University | Composto, método para inibir uma resposta inflamatória em um paciente, método para inibir inflamação em um paciente, método para inibir expressão de interferon ativada por dsdna em um mamífero, método para tratar metástase de câncer em um paciente e formulação farmacêutica |
| CA3125625A1 (en) * | 2019-01-04 | 2020-07-09 | Bellbrook Labs, Llc | Inhibitors of cgas activity as therapeutic agents |
| US12522603B2 (en) * | 2019-03-13 | 2026-01-13 | The Rockefeller University | Inhibitors of gas for treating autoinflammatory diseases and cancer metastasis |
-
2021
- 2021-09-23 AU AU2021349249A patent/AU2021349249A1/en not_active Abandoned
- 2021-09-23 CN CN202180065543.XA patent/CN116209442A/zh active Pending
- 2021-09-23 JP JP2023519165A patent/JP2023543254A/ja active Pending
- 2021-09-23 EP EP21873398.8A patent/EP4216940A4/en active Pending
- 2021-09-23 CA CA3196153A patent/CA3196153A1/en active Pending
- 2021-09-23 WO PCT/US2021/051670 patent/WO2022066851A1/en not_active Ceased
- 2021-09-23 US US18/027,602 patent/US20240018138A1/en active Pending
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