|
GB1360354A
(en)
|
1972-01-20 |
1974-07-17 |
Union International Co Ltd |
Chenodeoxycholic acid
|
|
JPS5826360B2
(ja)
|
1974-08-23 |
1983-06-02 |
エ−ザイ カブシキガイシヤ |
グリコケノデオキシコ−ルサンノ セイホウ
|
|
IT1221734B
(it)
|
1983-02-24 |
1990-07-12 |
Schiena Michele Giuseppe Di |
Ursodesossicolico solfato acido sale sodico
|
|
US5210272A
(en)
|
1990-02-16 |
1993-05-11 |
Prototek, Inc. |
Process for forming a fluoromethyl ketone
|
|
US5733566A
(en)
|
1990-05-15 |
1998-03-31 |
Alkermes Controlled Therapeutics Inc. Ii |
Controlled release of antiparasitic agents in animals
|
|
NZ245504A
(en)
|
1991-12-20 |
1995-08-28 |
Hoechst Ag |
Bile acid derivatives containing an ethylenically unsaturated grouping
|
|
IT1255450B
(it)
|
1992-06-30 |
1995-10-31 |
Montefarmaco Spa |
Uso di acidi biliari come agenti antivirali
|
|
EP0624593A3
(de)
|
1993-05-08 |
1995-06-07 |
Hoechst Ag |
Gallensäurederivate, Verfahren zu ihrer Herstellung und Verwendung dieser Verbindungen als Arzneimittel.
|
|
IT1270853B
(it)
|
1993-05-20 |
1997-05-13 |
Sanofi Elf |
Procedimento per la preparazione di derivati taurocolanici
|
|
EP0717631B1
(en)
|
1993-09-09 |
2003-07-09 |
Lorus Therapeutics Inc. |
Immunomodulating compositions from bile
|
|
US5695738A
(en)
|
1995-06-15 |
1997-12-09 |
Glycomed Incorporated |
Steroidal C-glycosides
|
|
US5763435A
(en)
|
1995-11-21 |
1998-06-09 |
Children's Hospital Medical Center |
Sulfate conjugates of ursodeoxycholic acid, and their beneficial use in inflammatory disorders
|
|
CA2206047A1
(en)
|
1997-05-23 |
1998-11-23 |
Romeo Rang (Deceased) |
Immunomodulating compositions for the treatment of viral disorders
|
|
DE19849722A1
(de)
|
1998-10-28 |
2000-05-04 |
Aventis Pharma Gmbh |
Substituierte Phenyl-alkenoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
|
|
CN1187364C
(zh)
|
1999-04-30 |
2005-02-02 |
亚其发展公司 |
类固醇衍生物
|
|
DE19941764A1
(de)
|
1999-09-02 |
2001-03-15 |
Aventis Pharma Gmbh |
Substituierte Acylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikamente oder Diagnostika sowie sie enthaltende Medikamente
|
|
SK3862002A3
(en)
|
1999-09-22 |
2003-01-09 |
Aventis Pharma Gmbh |
4-Benzylaminoquinoline conjugates with bile acid and their heteroanalogues, methods for producing the same, medicaments containing these compounds and their use
|
|
US6451355B1
(en)
|
2000-07-17 |
2002-09-17 |
Howard M. Reisner |
Composition to treat diabetes
|
|
ITTO20020102A1
(it)
|
2002-02-06 |
2003-08-06 |
Abc Ist Biolog Chem Spa |
Procedimento per la preparazione dell'acido ursodesossicolico disolfato e suoi sali farmaceuticamente accettabili.
|
|
ITMI20030822A1
(it)
|
2003-04-18 |
2004-10-19 |
Erregierre Spa |
Processo per la preparazione dell'acido ursodesossicolico
|
|
US20070032464A1
(en)
|
2004-10-08 |
2007-02-08 |
Shutsung Liao |
Methods of treating cancers
|
|
CA2608052A1
(en)
|
2005-05-10 |
2006-11-16 |
Laboratoires Fournier S.A. |
Novel use of liver x receptor agonists
|
|
US9295677B2
(en)
|
2008-02-26 |
2016-03-29 |
Qing Bile Therapeutics Inc. |
Polyhydroxylated bile acids for treatment of biliary disorders
|
|
CA2758023A1
(en)
|
2008-04-09 |
2009-10-15 |
Cornell University |
Commensal bacteria as signal mediators within a mammalian host
|
|
CA2744697C
(en)
|
2008-11-26 |
2016-06-21 |
Satiogen Pharmaceuticals, Inc. |
Use of compositions comprising bile acids, salts, and mimics thereof for the treatment of obesity or diabetes
|
|
WO2012151252A2
(en)
|
2011-05-02 |
2012-11-08 |
Biokier, Inc. |
Composition and method for treatment of diabetes
|
|
IT1393095B1
(it)
|
2009-02-19 |
2012-04-11 |
Prodotti Chimici Alimentari |
Processo per la sintesi del sale disodico dell'acido ursodesossicolico 3,7-disolfato.
|
|
US8829213B2
(en)
|
2009-07-29 |
2014-09-09 |
The University Of Chicago |
Liver X receptor agonists
|
|
EP2470553B1
(en)
|
2009-08-25 |
2024-06-19 |
Qing Bile Therapeutics Inc. |
Polyhydroxylated bile acids for treatment of biliary disorders
|
|
CA2859965A1
(en)
|
2011-12-21 |
2013-06-27 |
Ardelyx, Inc. |
Non-systemic tgr5 agonists
|
|
WO2013113680A1
(en)
|
2012-02-03 |
2013-08-08 |
Aarhus Universitet |
Radiolabeled bile acids and bile acid derivatives
|
|
US20140206657A1
(en)
|
2013-01-18 |
2014-07-24 |
City Of Hope |
Bile acid analog tgr5 agonists
|
|
US9580459B2
(en)
|
2013-04-26 |
2017-02-28 |
Metselex, Inc. |
Water-soluble ursodeoxycholic acid prodrugs
|
|
US10538550B2
(en)
|
2014-11-19 |
2020-01-21 |
NZP UK Limited |
6.alpha.-alkyl-3,7-dione steroids as intermediates for the production of steroidal FXR modulators
|
|
US20190125745A1
(en)
|
2014-12-17 |
2019-05-02 |
Rgenix, Inc. |
Treatment and diagnosis of cancer
|
|
AR103260A1
(es)
*
|
2014-12-23 |
2017-04-26 |
4D Pharma Res Ltd |
Modulación inmunitaria
|
|
TW201704251A
(zh)
*
|
2015-04-29 |
2017-02-01 |
正大天晴藥業集團股份有限公司 |
鵝去氧膽酸衍生物
|
|
EP3310801B1
(en)
|
2015-06-19 |
2021-04-07 |
Intercept Pharmaceuticals, Inc. |
Tgr5 modulators and methods of use thereof
|
|
TWI618714B
(zh)
*
|
2015-08-27 |
2018-03-21 |
中央研究院 |
涎酸轉移酶抑制劑及其用途
|
|
CN106478759A
(zh)
|
2015-08-31 |
2017-03-08 |
陕西合成药业股份有限公司 |
奥贝胆酸衍生物及其制备方法和用途
|
|
TWI773657B
(zh)
|
2015-12-18 |
2022-08-11 |
美商亞德利克斯公司 |
作爲非全身tgr5促效劑之經取代之4-苯基吡啶化合物
|
|
WO2017142895A1
(en)
*
|
2016-02-15 |
2017-08-24 |
Regents Of The University Of Minnesota |
Compositions and methods for treating clostridium associated diseases
|
|
US20170233431A1
(en)
|
2016-02-17 |
2017-08-17 |
City Of Hope |
Bile acid derivatives and methods for synthesis and use
|
|
RU2665685C1
(ru)
|
2017-09-18 |
2018-09-04 |
Общество с ограниченной ответственностью "МДК Медика" |
Способ получения алкиламмонийных солей алкилсерных кислот
|
|
JP2020536566A
(ja)
*
|
2017-10-13 |
2020-12-17 |
バッテル メモリアル インスティチュート |
胆汁酸塩ヒドロラーゼプローブならびにその製造方法および使用方法
|
|
US20210122780A1
(en)
|
2018-03-29 |
2021-04-29 |
Metselex, Inc. |
Compositions for the prevention and treatment of parkinson's disease
|
|
US12186329B2
(en)
|
2018-08-23 |
2025-01-07 |
President And Fellows Of Harvard College |
Compositions and methods related to cholic acid 7-sulfate as a treatment for diabetes
|
|
EP3890745B1
(en)
|
2018-12-04 |
2025-11-19 |
President and Fellows of Harvard College |
Synthetic derivatives of cholic acid 7-sulfate and uses thereof
|
|
WO2021226447A1
(en)
|
2020-05-08 |
2021-11-11 |
President And Fellows Of Harvard College |
Methods for inducing bile acid sulfotransferase sult2a for treating metabolic disorders
|