JP2023536902A5 - - Google Patents

Info

Publication number
JP2023536902A5
JP2023536902A5 JP2023507555A JP2023507555A JP2023536902A5 JP 2023536902 A5 JP2023536902 A5 JP 2023536902A5 JP 2023507555 A JP2023507555 A JP 2023507555A JP 2023507555 A JP2023507555 A JP 2023507555A JP 2023536902 A5 JP2023536902 A5 JP 2023536902A5
Authority
JP
Japan
Prior art keywords
promoter
vector
expression cassette
pharmaceutical composition
identity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023507555A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023536902A (ja
JP7853952B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/044416 external-priority patent/WO2022031760A1/en
Publication of JP2023536902A publication Critical patent/JP2023536902A/ja
Publication of JP2023536902A5 publication Critical patent/JP2023536902A5/ja
Application granted granted Critical
Publication of JP7853952B2 publication Critical patent/JP7853952B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023507555A 2020-08-05 2021-08-03 Glut1発現のためのアデノ随伴ウイルスベクターおよびその使用 Active JP7853952B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063061726P 2020-08-05 2020-08-05
US63/061,726 2020-08-05
PCT/US2021/044416 WO2022031760A1 (en) 2020-08-05 2021-08-03 Adeno-associated viral vector for glut1 expression and uses thereof

Publications (3)

Publication Number Publication Date
JP2023536902A JP2023536902A (ja) 2023-08-30
JP2023536902A5 true JP2023536902A5 (https=) 2024-08-13
JP7853952B2 JP7853952B2 (ja) 2026-04-30

Family

ID=80118621

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023507555A Active JP7853952B2 (ja) 2020-08-05 2021-08-03 Glut1発現のためのアデノ随伴ウイルスベクターおよびその使用

Country Status (11)

Country Link
US (1) US20230272422A1 (https=)
EP (1) EP4192960A4 (https=)
JP (1) JP7853952B2 (https=)
KR (1) KR20230043123A (https=)
CN (1) CN116113700A (https=)
AU (1) AU2021321412A1 (https=)
BR (1) BR112023001418A2 (https=)
CA (1) CA3184233A1 (https=)
IL (1) IL300185A (https=)
MX (1) MX2023001419A (https=)
WO (1) WO2022031760A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE055862T2 (hu) 2016-04-20 2021-12-28 Centro De Investig Energeticas Készítmények és eljárások PKLR fokozott génexpressziójára
SG11202002263TA (en) 2017-10-16 2020-04-29 Centro De Investigaciones Energeticas Medioambientales Y Tecnologicas Lentiviral vectors for delivery of pklr to treat pyruvate kinase deficiency
WO2019200167A1 (en) 2018-04-11 2019-10-17 Rocket Pharmaceuticals, Ltd. Compositions and methods for stem cell transplant
MX2020011386A (es) 2018-04-27 2021-01-29 Spacecraft Seven Llc Terapia genica para la degeneracion del snc.
KR20230043869A (ko) 2020-08-07 2023-03-31 스페이스크래프트 세븐, 엘엘씨 Aav 벡터를 사용한 플라코필린-2(pkp2) 유전자 요법
CN114457045B (zh) * 2022-02-25 2023-07-14 中国人民解放军军事科学院军事医学研究院 抑制Slc2a1的RNAi腺相关病毒及其制备和应用
WO2025082176A1 (zh) * 2023-10-19 2025-04-24 北京脑科学与类脑研究所 一种脑血管内皮细胞嵌合型启动子和重组表达载体及应用
WO2025137149A1 (en) * 2023-12-19 2025-06-26 The Trustees Of Columbia University In The City Of New York Compositions and methods for therapeutic vectors targeting brain microvasculature

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
US20070161031A1 (en) * 2005-12-16 2007-07-12 The Board Of Trustees Of The Leland Stanford Junior University Functional arrays for high throughput characterization of gene expression regulatory elements
KR20240119152A (ko) 2015-03-10 2024-08-06 더 트러스티스 오브 컬럼비아 유니버시티 인 더 시티 오브 뉴욕 재조합 glut1 아데노-관련 바이러스 벡터 작제물 및 glut1 발현을 회복하기 위한 관련된 방법
US11446375B2 (en) 2015-12-22 2022-09-20 Vrije Universiteit Brussel Endothelium-specific nucleic acid regulatory elements and methods and use thereof
JP6996728B2 (ja) * 2016-01-07 2022-01-17 学校法人自治医科大学 グルコーストランスポーター1発現用アデノ随伴ウイルスベクター

Similar Documents

Publication Publication Date Title
JP2023536902A5 (https=)
JP2023538519A5 (https=)
CN106488984B (zh) 一种治疗周围神经病变以及运动神经元疾病的方法
JP2023536618A5 (https=)
JP7853952B2 (ja) Glut1発現のためのアデノ随伴ウイルスベクターおよびその使用
JP2020533959A5 (https=)
RU2018116076A (ru) Модифицированные гены атаксии фридрейха и векторы для генной терапии
JP2025505662A5 (https=)
JP2022535749A5 (https=)
JP2021533805A5 (https=)
JP2022541070A5 (https=)
JP2023535576A5 (https=)
JP2022531861A5 (https=)
JP2022525302A5 (https=)
JP2025508968A (ja) 血液脳関門を横断するための組成物および方法
WO2019227219A1 (en) Adeno-associated viral vector-mediated gene therapy for treating fragile x-associated disorders
JP2024546103A5 (https=)
JP2023537980A5 (https=)
JP2022541793A5 (https=)
JP2024545507A5 (https=)
JP2021520811A5 (https=)
JP2022525848A5 (https=)
JP2024515626A5 (https=)
WO2024015877A2 (en) Novel aav3b capsid variants with enhanced hepatocyte tropism
CN118955652A (zh) 腺相关病毒衣壳蛋白、包含其的腺相关病毒及应用