JP2023535926A5 - - Google Patents

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Publication number
JP2023535926A5
JP2023535926A5 JP2023504487A JP2023504487A JP2023535926A5 JP 2023535926 A5 JP2023535926 A5 JP 2023535926A5 JP 2023504487 A JP2023504487 A JP 2023504487A JP 2023504487 A JP2023504487 A JP 2023504487A JP 2023535926 A5 JP2023535926 A5 JP 2023535926A5
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JP
Japan
Prior art keywords
branched
linear
independently selected
alkyl
hydrogen atom
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2023504487A
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English (en)
Japanese (ja)
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JP7797473B2 (ja
JP2023535926A (ja
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Priority claimed from PCT/CN2021/107774 external-priority patent/WO2022017440A1/zh
Publication of JP2023535926A publication Critical patent/JP2023535926A/ja
Publication of JP2023535926A5 publication Critical patent/JP2023535926A5/ja
Priority to JP2025280400A priority Critical patent/JP2026065019A/ja
Application granted granted Critical
Publication of JP7797473B2 publication Critical patent/JP7797473B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2023504487A 2020-07-22 2021-07-22 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途 Active JP7797473B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025280400A JP2026065019A (ja) 2020-07-22 2025-12-24 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN202010708352 2020-07-22
CN202010708352.8 2020-07-22
CN202110364023 2021-04-03
CN202110364023.0 2021-04-03
PCT/CN2021/107774 WO2022017440A1 (zh) 2020-07-22 2021-07-22 5-ht 2a受体抑制剂或反向激动剂及其制备方法和应用

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025280400A Division JP2026065019A (ja) 2020-07-22 2025-12-24 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途

Publications (3)

Publication Number Publication Date
JP2023535926A JP2023535926A (ja) 2023-08-22
JP2023535926A5 true JP2023535926A5 (https=) 2024-07-24
JP7797473B2 JP7797473B2 (ja) 2026-01-13

Family

ID=79728503

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023504487A Active JP7797473B2 (ja) 2020-07-22 2021-07-22 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途
JP2025280400A Pending JP2026065019A (ja) 2020-07-22 2025-12-24 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025280400A Pending JP2026065019A (ja) 2020-07-22 2025-12-24 ５－ｈｔ２ａ受容体阻害剤又は逆作動薬、その調製方法、及びその用途

Country Status (5)

Country Link
US (1) US20230348421A1 (https=)
EP (1) EP4186893A4 (https=)
JP (2) JP7797473B2 (https=)
CN (2) CN114728933B (https=)
WO (1) WO2022017440A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115605202B (zh) 2020-03-26 2025-10-28 盐野义制药株式会社 具有血清素受体结合活性的芳香族杂环衍生物
US20240083872A1 (en) * 2020-12-28 2024-03-14 Shionogi & Co., Ltd. Cyclic amine derivatives having serotonin receptor binding activity
AU2023319750A1 (en) * 2022-08-03 2025-02-13 Luye Innomind Pharma Shijiazhuang Co., Ltd. 5-ht2a receptor inverse agonist, and preparation method therefor and use thereof
CN115850204B (zh) * 2022-11-26 2024-01-19 烟台大学 四氢苯并噻吩衍生物及其制备方法和应用
WO2025162237A1 (zh) * 2024-02-02 2025-08-07 绿叶嘉奥制药石家庄有限公司 一种5-ht2a受体反向激动剂的盐型、晶型及其制备方法和应用

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US3829307A (en) * 1971-04-30 1974-08-13 Stauffer Chemical Co 1-picolyl-3-phenyl ureas and their utility as herbicides
US3991195A (en) * 1974-05-06 1976-11-09 Stauffer Chemical Company Method of controlling bacteria
DK485176A (da) * 1975-11-12 1977-05-13 Merck & Co Inc Fremgangsmade til fremstilling af pyridylurinstoffer
FR2802206B1 (fr) * 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
RU2002126554A (ru) * 2000-03-06 2004-03-20 Акадиа Фармасьютикалз, Инк. (Us) Азациклические соединения для применения при лечении опосредованных серотонином заболеваний
CN100509804C (zh) * 2002-06-24 2009-07-08 阿卡蒂亚药品公司 N-取代哌啶衍生物作为血清素受体试剂
PT1587789E (pt) 2003-01-16 2008-12-16 Acadia Pharm Inc Agonistas inversos selectivos para receptores 2a/2c da serotonina como agentes terapêuticos para doenças neurodegenerativas
US20050261278A1 (en) * 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
US20120183600A1 (en) * 2007-01-16 2012-07-19 Chien-Hung Chen Novel composition for treating metabolic syndrome and other conditions
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WO2009039461A2 (en) * 2007-09-21 2009-03-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
JP5567483B2 (ja) * 2007-10-09 2014-08-06 ダウ アグロサイエンシィズ エルエルシー 殺虫性置換アジニル誘導体
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TWI703130B (zh) * 2014-03-07 2020-09-01 瑞士商赫爾辛保健股份有限公司 對位取代的不對稱脲及其醫療用途
WO2017172757A1 (en) * 2016-03-29 2017-10-05 Acadia Pharmaceuticals Inc. 5-ht2a serotonin receptor inverse agonists or antagonists for use in reducing amyloid-beta peptides and accumulation of amyloid plaques
CN109111385B (zh) * 2017-06-23 2023-06-30 上海翰森生物医药科技有限公司 5-ht2a受体抑制剂及其制备方法和应用
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CN113214141B (zh) * 2020-01-21 2022-04-08 瀚远医药有限公司 5ht2a受体拮抗剂及其制备和应用
CN115605202B (zh) * 2020-03-26 2025-10-28 盐野义制药株式会社 具有血清素受体结合活性的芳香族杂环衍生物
AU2023319750A1 (en) * 2022-08-03 2025-02-13 Luye Innomind Pharma Shijiazhuang Co., Ltd. 5-ht2a receptor inverse agonist, and preparation method therefor and use thereof

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