JP2023530778A5 - - Google Patents
Info
- Publication number
- JP2023530778A5 JP2023530778A5 JP2023502874A JP2023502874A JP2023530778A5 JP 2023530778 A5 JP2023530778 A5 JP 2023530778A5 JP 2023502874 A JP2023502874 A JP 2023502874A JP 2023502874 A JP2023502874 A JP 2023502874A JP 2023530778 A5 JP2023530778 A5 JP 2023530778A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- compound
- alkyl
- salt
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024218609A JP7645431B2 (ja) | 2020-03-27 | 2024-12-13 | Ｍｔｏｒｃ１モジュレーターおよびその使用 |
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063001144P | 2020-03-27 | 2020-03-27 | |
| US202063001177P | 2020-03-27 | 2020-03-27 | |
| US202063001187P | 2020-03-27 | 2020-03-27 | |
| US63/001,187 | 2020-03-27 | ||
| US63/001,144 | 2020-03-27 | ||
| US63/001,177 | 2020-03-27 | ||
| US202063019176P | 2020-05-01 | 2020-05-01 | |
| US63/019,176 | 2020-05-01 | ||
| US202063054768P | 2020-07-21 | 2020-07-21 | |
| US202063054763P | 2020-07-21 | 2020-07-21 | |
| US202063054762P | 2020-07-21 | 2020-07-21 | |
| US63/054,762 | 2020-07-21 | ||
| US63/054,763 | 2020-07-21 | ||
| US63/054,768 | 2020-07-21 | ||
| PCT/US2021/024536 WO2021195599A1 (en) | 2020-03-27 | 2021-03-26 | Mtorc1 modulators and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024218609A Division JP7645431B2 (ja) | 2020-03-27 | 2024-12-13 | Ｍｔｏｒｃ１モジュレーターおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023530778A JP2023530778A (ja) | 2023-07-19 |
| JP2023530778A5 true JP2023530778A5 (https=) | 2024-04-04 |
| JP7606591B2 JP7606591B2 (ja) | 2024-12-25 |
Family
ID=77892684
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023502874A Active JP7606591B2 (ja) | 2020-03-27 | 2021-03-26 | Ｍｔｏｒｃ１モジュレーターおよびその使用 |
| JP2024218609A Active JP7645431B2 (ja) | 2020-03-27 | 2024-12-13 | Ｍｔｏｒｃ１モジュレーターおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024218609A Active JP7645431B2 (ja) | 2020-03-27 | 2024-12-13 | Ｍｔｏｒｃ１モジュレーターおよびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11634432B2 (https=) |
| EP (1) | EP4126229A4 (https=) |
| JP (2) | JP7606591B2 (https=) |
| KR (2) | KR20250065937A (https=) |
| CN (2) | CN115776907B (https=) |
| AU (2) | AU2021241718B2 (https=) |
| CA (1) | CA3173722A1 (https=) |
| IL (1) | IL296828A (https=) |
| MX (1) | MX2022011964A (https=) |
| WO (1) | WO2021195599A1 (https=) |
| ZA (1) | ZA202210888B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019241789A1 (en) | 2018-06-15 | 2019-12-19 | Navitor Pharmaceuticals, Inc. | Rapamycin analogs and uses thereof |
| IL285067B2 (en) | 2019-01-22 | 2025-02-01 | Aeovian Pharmaceuticals Inc | MTORC Modulators and Their Uses |
| AU2020397938A1 (en) | 2019-12-05 | 2022-06-23 | Janssen Pharmaceutica Nv | Rapamycin analogs and uses thereof |
| CN115776907B (zh) | 2020-03-27 | 2025-02-25 | 艾奥维安制药公司 | Mtorc1调节剂及其用途 |
| CN121426814A (zh) * | 2020-07-21 | 2026-01-30 | 艾奥维安制药公司 | Mtorc1调节剂及其用途 |
| EP4688148A1 (en) * | 2023-04-07 | 2026-02-11 | Regeneron Pharmaceuticals, Inc. | Selective rapamycin analogs and uses thereof |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA935112B (en) | 1992-07-17 | 1994-02-08 | Smithkline Beecham Corp | Rapamycin derivatives |
| US5258389A (en) | 1992-11-09 | 1993-11-02 | Merck & Co., Inc. | O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives |
| SK78196A3 (en) | 1993-12-17 | 1997-02-05 | Sandoz Ag | Rapamycin demethoxy-derivatives, preparation method thereof and pharmaceutical agent containing them |
| US6187757B1 (en) * | 1995-06-07 | 2001-02-13 | Ariad Pharmaceuticals, Inc. | Regulation of biological events using novel compounds |
| JP2002508971A (ja) * | 1998-01-15 | 2002-03-26 | アリアド・ジーン・セラピューティクス・インコーポレーテッド | 多量体キメラ蛋白質を使用する生物学的イベントの調節 |
| ATE264863T1 (de) * | 1999-08-24 | 2004-05-15 | Ariad Gene Therapeutics Inc | 28-epirapaloge |
| WO2006136175A2 (en) | 2005-06-22 | 2006-12-28 | Lifecycle Pharma A/S | Pharmaceutical compositions comprising tacrolimus and a cyp3a4 inhibitor |
| GB0601406D0 (en) | 2006-01-24 | 2006-03-08 | Novartis Ag | Organic Compounds |
| US20110098241A1 (en) | 2008-04-14 | 2011-04-28 | Poniard Pharmaceuticals, Inc. | Rapamycin analogs as anti-cancer agents |
| CN103391780B (zh) * | 2011-02-16 | 2015-08-19 | 诺瓦提斯公司 | 用于治疗神经变性疾病的治疗剂的组合物 |
| US20160138027A1 (en) * | 2013-03-14 | 2016-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of diseases and conditions associated with dysregulation of mammalian target of rapamycin complex 1 (mtorc1) |
| ES2857226T3 (es) * | 2014-03-15 | 2021-09-28 | Novartis Ag | Receptor de antígeno quimérico regulable |
| CN113620978A (zh) | 2014-09-11 | 2021-11-09 | 加利福尼亚大学董事会 | mTORC1抑制剂 |
| JP6793652B2 (ja) | 2015-09-03 | 2020-12-02 | 日本化薬株式会社 | ラパマイシン又はその誘導体を含有する医薬組成物 |
| US10683308B2 (en) * | 2015-09-11 | 2020-06-16 | Navitor Pharmaceuticals, Inc. | Rapamycin analogs and uses thereof |
| CN108926533B (zh) | 2017-05-24 | 2022-03-25 | 江苏天士力帝益药业有限公司 | 一种替西罗莫司脂质体及其制备方法 |
| US10478561B2 (en) | 2017-08-03 | 2019-11-19 | Minhong Yu | Wireless transmission system with integrated sensing capability |
| AR112834A1 (es) | 2017-09-26 | 2019-12-18 | Novartis Ag | Derivados de rapamicina |
| WO2019241789A1 (en) | 2018-06-15 | 2019-12-19 | Navitor Pharmaceuticals, Inc. | Rapamycin analogs and uses thereof |
| WO2020076738A2 (en) | 2018-10-12 | 2020-04-16 | Bellicum Pharmaceuticals, Inc | Protein-binding compounds |
| HRP20250197T1 (hr) | 2018-12-18 | 2025-04-11 | Novartis Ag | Derivati rapamicina |
| IL285067B2 (en) | 2019-01-22 | 2025-02-01 | Aeovian Pharmaceuticals Inc | MTORC Modulators and Their Uses |
| AU2020397938A1 (en) | 2019-12-05 | 2022-06-23 | Janssen Pharmaceutica Nv | Rapamycin analogs and uses thereof |
| CN115776907B (zh) | 2020-03-27 | 2025-02-25 | 艾奥维安制药公司 | Mtorc1调节剂及其用途 |
| CN121426814A (zh) | 2020-07-21 | 2026-01-30 | 艾奥维安制药公司 | Mtorc1调节剂及其用途 |
| US20220267352A1 (en) | 2021-01-22 | 2022-08-25 | Anakuria Therapeutics, Inc. | Rapamycin analogs and uses thereof |
-
2021
- 2021-03-26 CN CN202180038254.0A patent/CN115776907B/zh active Active
- 2021-03-26 EP EP21775952.1A patent/EP4126229A4/en active Pending
- 2021-03-26 IL IL296828A patent/IL296828A/en unknown
- 2021-03-26 CA CA3173722A patent/CA3173722A1/en active Pending
- 2021-03-26 AU AU2021241718A patent/AU2021241718B2/en active Active
- 2021-03-26 CN CN202510123209.5A patent/CN119954829A/zh active Pending
- 2021-03-26 MX MX2022011964A patent/MX2022011964A/es unknown
- 2021-03-26 KR KR1020257014654A patent/KR20250065937A/ko active Pending
- 2021-03-26 WO PCT/US2021/024536 patent/WO2021195599A1/en not_active Ceased
- 2021-03-26 KR KR1020227036354A patent/KR102805250B1/ko active Active
- 2021-03-26 JP JP2023502874A patent/JP7606591B2/ja active Active
-
2022
- 2022-03-01 US US17/683,549 patent/US11634432B2/en active Active
- 2022-06-03 US US17/832,240 patent/US11603377B2/en active Active
- 2022-10-03 ZA ZA2022/10888A patent/ZA202210888B/en unknown
-
2023
- 2023-03-08 US US18/180,517 patent/US20240002399A1/en active Pending
-
2024
- 2024-12-13 JP JP2024218609A patent/JP7645431B2/ja active Active
-
2025
- 2025-06-25 AU AU2025204768A patent/AU2025204768C1/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023530778A5 (https=) | ||
| RU2486179C2 (ru) | Аналоги тиазолидиндиона для лечения диабета и дислипидемии | |
| RU2570424C2 (ru) | Рапп-поддерживающие тиазолидиндионы и их комбинации для лечения нейродегенеративных заболеваний | |
| RU2001120726A (ru) | Комбинация ингибиторов fbpазы и сенсибилизаторов инсулина для лечения диабета | |
| RU2227749C2 (ru) | Комбинация ингибиторов fbpазы и сенсибилизаторов инсулина для лечения диабета | |
| RU2007131430A (ru) | Пролекарства соединений 2,4-пиримидиндиамина и их применение | |
| RU2000103491A (ru) | Конденсированные производные 1,2,4-тиадиазина, их получение и применение. | |
| HUE034919T2 (en) | 2,4,5,6-substituted 3,6-dihydropyrimidine derivatives such as hepatitis B virus (HBV) polymerase inhibitors, for example, for the treatment of chronic hepatitis | |
| RU99103617A (ru) | Новые пара-терфенильные соединения | |
| AR033516A1 (es) | Acidos malonamicos y derivados de los mismos como ligandos de receptor tiroideo, su uso en la fabricacion de medicamentos y composiciones que los contienen | |
| RU2008136187A (ru) | Новое производное кумарина, обладающее противоопухолевой активностью | |
| RU2015111133A (ru) | Ингибиторы тирозинкиназы брутона | |
| JP7139568B2 (ja) | ジヒドロピリミジン化合物並びにその調製方法及び使用 | |
| CA2111447C (en) | Hypoglycemic thiazolidinediones and intermediates | |
| CA3186645A1 (en) | Antiplatelet drugs and uses thereof | |
| JP2024520654A5 (https=) | ||
| CZ300694A3 (en) | Substituted 2beta-morpholinandrostane derivatives, process of their preparation, their use for preparing pharmaceutical preparations and pharmaceutical compositions containing thereof | |
| KR950701328A (ko) | 메일라드 반응 억제제로서의 티아졸 또는 이미다졸 유도체(Thiazole or imidazole derivatives as Maillard reaction inhibitors) | |
| RU2008125040A (ru) | ПРОИЗВОДНЫЕ АРИЛ-ИЗОКСАЗОЛ-4-ИЛ-ИМИДАЗО[1.5-a]ПИРИДИНА | |
| RU98117245A (ru) | 2-(арилфенил)аминоимидазолиновые производные | |
| JP2022554330A5 (https=) | ||
| JP2026503618A5 (https=) | ||
| RU2005136434A (ru) | 7-азаиндолы и их применение в качестве лекарственых средств | |
| KR970010766A (ko) | 피페리디닐메틸옥사졸리딘온 | |
| JP2024545220A5 (https=) |