JP2023530663A5 - - Google Patents

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Publication number
JP2023530663A5
JP2023530663A5 JP2022576392A JP2022576392A JP2023530663A5 JP 2023530663 A5 JP2023530663 A5 JP 2023530663A5 JP 2022576392 A JP2022576392 A JP 2022576392A JP 2022576392 A JP2022576392 A JP 2022576392A JP 2023530663 A5 JP2023530663 A5 JP 2023530663A5
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JP
Japan
Prior art keywords
amino acid
antigen
binding protein
seq
acid sequence
Prior art date
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Granted
Application number
JP2022576392A
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English (en)
Japanese (ja)
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JP2023530663A (ja
JP7798805B2 (ja
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Priority claimed from PCT/US2021/036347 external-priority patent/WO2021252455A1/en
Publication of JP2023530663A publication Critical patent/JP2023530663A/ja
Publication of JP2023530663A5 publication Critical patent/JP2023530663A5/ja
Application granted granted Critical
Publication of JP7798805B2 publication Critical patent/JP7798805B2/ja
Active legal-status Critical Current
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JP2022576392A 2020-06-08 2021-06-08 抗TGFβ抗体及びその治療的使用 Active JP7798805B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063036092P 2020-06-08 2020-06-08
US63/036,092 2020-06-08
PCT/US2021/036347 WO2021252455A1 (en) 2020-06-08 2021-06-08 ANTI-TGFβ ANTIBODIES AND THERAPEUTIC USES THEREOF

Publications (3)

Publication Number Publication Date
JP2023530663A JP2023530663A (ja) 2023-07-19
JP2023530663A5 true JP2023530663A5 (enExample) 2024-12-16
JP7798805B2 JP7798805B2 (ja) 2026-01-14

Family

ID=76708478

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022576392A Active JP7798805B2 (ja) 2020-06-08 2021-06-08 抗TGFβ抗体及びその治療的使用

Country Status (13)

Country Link
US (1) US20220119513A1 (enExample)
EP (1) EP4161654A1 (enExample)
JP (1) JP7798805B2 (enExample)
KR (1) KR20230022974A (enExample)
CN (1) CN115803342A (enExample)
AU (1) AU2021287868A1 (enExample)
BR (1) BR112022024195A2 (enExample)
CA (1) CA3186707A1 (enExample)
CO (1) CO2023000068A2 (enExample)
DK (1) DK202370008A1 (enExample)
MX (1) MX2022015609A (enExample)
PH (1) PH12022500030A1 (enExample)
WO (1) WO2021252455A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116096741B (zh) 2020-07-10 2024-10-18 因外泰克斯公司 用于延长治疗剂在猫科动物中的半衰期的组合物和使用方法
CA3194936A1 (en) 2020-09-28 2022-03-31 Zoetis Services Llc Canine antibody variants
CA3232382A1 (en) * 2021-09-27 2023-03-30 Zoetis Services Llc Anti- tgf.beta.1,2,3 antibodies and therapeutic uses thereof
KR20250137204A (ko) 2022-12-27 2025-09-17 인베티엑스 인코포레이티드 신생아 fc 수용체(fcrn)에 대한 결합이 변경된 폴리펩타이드 및 사용 방법
AU2023415535A1 (en) 2022-12-27 2025-07-10 Invetx, Inc. Polypeptides with altered binding to neonatal fc receptor (fcrn) and methods of use
CN121002059A (zh) 2023-01-20 2025-11-21 因外泰克斯公司 用于伴侣动物的双特异性结合剂
CN117106082B (zh) * 2023-09-15 2024-10-29 成都蓉生药业有限责任公司 一种抗TGFβ的人源化纳米抗体

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・2・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
GB8905669D0 (en) 1989-03-13 1989-04-26 Celltech Ltd Modified antibodies
EP0590058B1 (en) 1991-06-14 2003-11-26 Genentech, Inc. HUMANIZED Heregulin ANTIBODy
US5350576A (en) 1991-09-13 1994-09-27 Mycogen Corporation Bacillus thuringiensis isolates for controlling acarides
US6194167B1 (en) 1997-02-18 2001-02-27 Washington State University Research Foundation ω-3 fatty acid desaturase
MXPA01009363A (es) 1999-03-18 2002-06-04 Merck Patent Gmbh Proteina para bloquear la adhesion de plaquetas.
US6492497B1 (en) * 1999-04-30 2002-12-10 Cambridge Antibody Technology Limited Specific binding members for TGFbeta1
EP1130098A3 (en) 2000-02-29 2003-09-10 Pfizer Products Inc. Mammalian osteoregulins
US20030031671A1 (en) 2001-08-01 2003-02-13 Sydney Welt Methods of treating colon cancer utilizing tumor-specific antibodies
CA2469833C (en) 2001-12-21 2008-05-20 Idexx Laboratories, Inc. Canine immunoglobulin variable domains, caninized antibodies, and methods for making and using them
CA2632799A1 (en) * 2005-12-23 2007-07-05 Eli Lilly And Company Tgf-beta binding compositions
WO2013134365A1 (en) * 2012-03-08 2013-09-12 Ludwig Institute For Cancer Research Ltd TGF-β1 SPECIFIC ANTIBODIES AND METHODS AND USES THEREOF
JP6495884B2 (ja) * 2013-03-11 2019-04-03 ジェンザイム・コーポレーション 改変抗tgfベータ抗体および抗原結合フラグメント
TWI733661B (zh) * 2015-03-04 2021-07-21 美商健臻公司 以高親合性、結合性及特異性結合轉化生長因子-β1的經修飾IgG抗體
TWI726870B (zh) * 2015-03-04 2021-05-11 美商健臻公司 具有高親和性、結合性及專一性之結合轉形生長因子-β1的scFv-Fc二聚體
TW202506185A (zh) * 2017-01-20 2025-02-16 法商賽諾菲公司 抗TGF-β抗體及其用途
US20200392219A1 (en) * 2017-05-08 2020-12-17 Trustees Of Tufts College Extracellular vesicles comprising membrane-tethered tgf-beta, compositions and methods of use thereof
EP3877055A1 (en) * 2018-11-05 2021-09-15 Ludwig Institute for Cancer Research Ltd Humanized and variant tgf-beta1 specific antibodies and methods and uses thereof

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