JP2023530036A5 - - Google Patents

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Publication number
JP2023530036A5
JP2023530036A5 JP2023517829A JP2023517829A JP2023530036A5 JP 2023530036 A5 JP2023530036 A5 JP 2023530036A5 JP 2023517829 A JP2023517829 A JP 2023517829A JP 2023517829 A JP2023517829 A JP 2023517829A JP 2023530036 A5 JP2023530036 A5 JP 2023530036A5
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JP
Japan
Prior art keywords
amino acid
acid sequence
seq
specified
sequence specified
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2023517829A
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English (en)
Japanese (ja)
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JP2023530036A (ja
JP7650351B2 (ja
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Priority claimed from US17/199,205 external-priority patent/US11359023B2/en
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Publication of JP2023530036A publication Critical patent/JP2023530036A/ja
Publication of JP2023530036A5 publication Critical patent/JP2023530036A5/ja
Application granted granted Critical
Publication of JP7650351B2 publication Critical patent/JP7650351B2/ja
Active legal-status Critical Current
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JP2023517829A 2020-06-01 2021-06-01 非古典的hla-iとネオアンチゲンとを含む複合体を標的とする抗体、およびその使用方法 Active JP7650351B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063032747P 2020-06-01 2020-06-01
US63/032,747 2020-06-01
US17/199,205 2021-03-11
US17/199,205 US11359023B2 (en) 2020-06-01 2021-03-11 Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
PCT/US2021/035290 WO2021247607A1 (en) 2020-06-01 2021-06-01 Antibodies targeting a complex comprising non-classical hla-i and neoantigen and their methods of use

Publications (3)

Publication Number Publication Date
JP2023530036A JP2023530036A (ja) 2023-07-12
JP2023530036A5 true JP2023530036A5 (https=) 2023-08-02
JP7650351B2 JP7650351B2 (ja) 2025-03-24

Family

ID=75495114

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023517829A Active JP7650351B2 (ja) 2020-06-01 2021-06-01 非古典的hla-iとネオアンチゲンとを含む複合体を標的とする抗体、およびその使用方法

Country Status (20)

Country Link
US (4) US10981996B1 (https=)
EP (1) EP4157882A4 (https=)
JP (1) JP7650351B2 (https=)
KR (1) KR20230019468A (https=)
CN (1) CN116367865A (https=)
AR (1) AR122501A1 (https=)
AU (1) AU2021284275A1 (https=)
BR (1) BR112022024275A2 (https=)
CA (1) CA3174090A1 (https=)
CL (1) CL2022003336A1 (https=)
CO (1) CO2022018426A2 (https=)
CR (1) CR20220652A (https=)
DO (1) DOP2022000268A (https=)
EC (1) ECSP22097197A (https=)
IL (1) IL298020A (https=)
JO (1) JOP20220309A1 (https=)
MX (1) MX2022015114A (https=)
PE (1) PE20230306A1 (https=)
TW (1) TW202235439A (https=)
WO (1) WO2021247607A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210253713A1 (en) * 2018-07-23 2021-08-19 Abexxa Biologics, Inc. Antibodies targeting a complex comprising non-classical hla-i and neoantigen and their methods of use
CA3183756A1 (en) 2020-05-19 2021-11-25 Amgen Inc. Mageb2 binding constructs
US10981996B1 (en) * 2020-06-01 2021-04-20 Abexxa Biologics, Inc. Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
US11976120B2 (en) * 2020-06-01 2024-05-07 Boehringer Ingelheim International Gmbh Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
KR20250009591A (ko) * 2022-04-08 2025-01-17 티조나 테라퓨틱스 항-hla-g 항체 및 항-egfr 항체, 항-pd1 또는 항-pd-l1 항체, 및/또는 항-cd47을 함유하는 복합 치료법

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8039218B2 (en) * 2002-11-14 2011-10-18 John Wayne Cancer Institute Detection of cancer cells in body fluids
EP1872124A4 (en) * 2005-04-19 2008-06-11 Prediction Sciences Llc DIAGNOSIS MARKET FOR BREAST CANCER TREATMENT AND PROGRESSION AND METHOD OF USE THEREOF
EP1790664A1 (en) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
WO2010019921A2 (en) * 2008-08-15 2010-02-18 The Regents Of The University Of California Biomarkers for diagnosis and treatment of chronic lymphocytic leukemia
US20120178111A1 (en) * 2009-09-23 2012-07-12 Diamandis Eleftherios P Methods and compositions for the detection of lung cancers
EP2699603B1 (en) 2011-04-19 2016-03-02 The United States of America As Represented by the Secretary Department of Health and Human Services Human monoclonal antibodies specific for glypican-3 and use thereof
US10656156B2 (en) 2012-07-05 2020-05-19 Mepur Ravindranath Diagnostic and therapeutic potential of HLA-E monospecific monoclonal IgG antibodies directed against tumor cell surface and soluble HLA-E
EP2961770A1 (en) 2013-02-26 2016-01-06 Roche Glycart AG Bispecific t cell activating antigen binding molecules
IL263466B2 (en) 2013-12-17 2023-10-01 Genentech Inc Anti-CD3 antibodies and methods of using them
CN103773775B (zh) 2014-01-26 2015-11-18 江苏省农业科学院 一种人源抗虫基因及其编码的抗Cry1B毒素独特型单链抗体与应用
US9950077B2 (en) 2014-06-20 2018-04-24 Bioalliance C.V. Anti-folate receptor alpha (FRA) antibody-drug conjugates and methods of using thereof
US10329348B2 (en) 2014-10-23 2019-06-25 Innate Pharma Treatment of cancers using anti-NKG2A agents
US10544220B2 (en) 2015-01-08 2020-01-28 Genmab A/S Bispecific antibodies against CD3 and CD20
EP3475706B1 (en) 2016-06-27 2021-08-11 Juno Therapeutics, Inc. Mhc-e restricted epitopes, binding molecules and related methods and uses
EP3573997A4 (en) 2017-01-24 2020-12-09 Abexxa Biologics, Inc. METHODS AND COMPOSITIONS INTENDED TO TARGE A COMPLEX INCLUDING A NON-CLASSIC HLA-I AND A NEO-ANTIGEN IN THE TREATMENT OF CANCER
CN112351795A (zh) 2018-02-23 2021-02-09 安贝科思生物制剂公司 采用抗癌药剂和以包含非典型hla-i及新抗原复合物为靶点的抗体的联合抗癌疗法
US20210253713A1 (en) 2018-07-23 2021-08-19 Abexxa Biologics, Inc. Antibodies targeting a complex comprising non-classical hla-i and neoantigen and their methods of use
US20200291128A1 (en) 2020-05-18 2020-09-17 Abexxa Biologics, Inc. Antibodies and methods of use thereof
US10981997B1 (en) * 2020-06-01 2021-04-20 Abexxa Biologics, Inc. Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
US10981996B1 (en) * 2020-06-01 2021-04-20 Abexxa Biologics, Inc. Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use
US11976120B2 (en) * 2020-06-01 2024-05-07 Boehringer Ingelheim International Gmbh Antibodies targeting a complex comprising non-classical HLA-I and neoantigen and their methods of use

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